Signal transduction by M3 muscarinic acetylcholine receptor in prostate cancer.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 26870222)

Published in Oncol Lett on October 27, 2015

Authors

Liqiang Guo1, Yuqiang Liu1, Zhibo Ding2, Wendong Sun1, Mingzhen Yuan1

Author Affiliations

1: Department of Urology, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
2: Department of Urology, The Fourth People's Hospital of Jinan, Jinan, Shandong 250031, P.R. China.

Articles cited by this

Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet (2000) 336.52

Global cancer statistics. CA Cancer J Clin (2011) 185.92

KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res (2000) 117.00

Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol (2004) 101.91

Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics (2003) 100.88

Cancer statistics, 2012. CA Cancer J Clin (2012) 87.38

affy--analysis of Affymetrix GeneChip data at the probe level. Bioinformatics (2004) 32.08

The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature (2002) 18.30

The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists. Genome Biol (2007) 16.46

WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res (2005) 12.88

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer. J Clin Invest (2008) 10.74

STRING: a database of predicted functional associations between proteins. Nucleic Acids Res (2003) 9.45

The Myc/Max/Mad network and the transcriptional control of cell behavior. Annu Rev Cell Dev Biol (2000) 8.47

Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell (2003) 6.38

Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression. Cancer Cell (2005) 6.04

The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities. Eur J Cancer (2001) 5.96

The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat Rev Cancer (2004) 5.47

MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res (2007) 4.95

Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model. J Clin Invest (2008) 4.13

Why do hubs tend to be essential in protein networks? PLoS Genet (2006) 3.29

TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation. Oncogene (2008) 2.94

The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr Relat Cancer (2001) 2.76

Cytoscape: software for visualization and analysis of biological networks. Methods Mol Biol (2011) 2.43

Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion. Int J Cancer (2007) 2.00

Regulation of MAPKs by growth factors and receptor tyrosine kinases. Biochim Biophys Acta (2007) 1.97

Activated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulation. Proc Natl Acad Sci U S A (1990) 1.95

Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis. Oncogene (2009) 1.76

A MAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translation. Blood (2005) 1.56

Activation of MAPK cascades by G-protein-coupled receptors: the case of gonadotropin-releasing hormone receptor. Trends Endocrinol Metab (2000) 1.49

MicroRNA-34 mediates AR-dependent p53-induced apoptosis in prostate cancer. Cancer Biol Ther (2008) 1.48

Muscarinic receptors and ligands in cancer. Am J Physiol Cell Physiol (2008) 1.42

B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer. Cancer Res (2012) 1.15

Thromboxane A2 receptors in prostate carcinoma: expression and its role in regulating cell motility via small GTPase Rho. Cancer Res (2008) 1.01

Activation of MAPK signaling pathway is essential for Id-1 induced serum independent prostate cancer cell growth. Oncogene (2002) 0.99

Muscarinic cholinergic receptors promote growth of human prostate cancer cells. Prostate (1997) 0.99

The m3 muscarinic acetylcholine receptor is coupled to mitogen-activated protein kinase via protein kinase C and epidermal growth factor receptor kinase. Biochem J (2000) 0.98

Cholinergic innervation and muscarinic receptors in the human prostate. Eur Urol (2007) 0.94

Cholinergic innervation and function in the prostate gland. Pharmacol Ther (2002) 0.91

Integrated analysis reveals critical genomic regions in prostate tumor microenvironment associated with clinicopathologic phenotypes. Clin Cancer Res (2012) 0.86

Contractions of the mouse prostate elicited by acetylcholine are mediated by M(3) muscarinic receptors. J Pharmacol Exp Ther (2011) 0.77