Published in J Pharmacol Exp Ther on September 01, 2011
Age-related changes in the innervation of the prostate gland: implications for prostate cancer initiation and progression. Organogenesis (2013) 0.82
Signal transduction by M3 muscarinic acetylcholine receptor in prostate cancer. Oncol Lett (2015) 0.75
Differences in time to peak carbachol-induced contractions between circular and longitudinal smooth muscles of mouse ileum. Naunyn Schmiedebergs Arch Pharmacol (2015) 0.75
NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes. Nat Methods (2011) 2.29
Embryonic stem cells as a source of models for drug discovery. Nat Rev Drug Discov (2007) 1.82
Two distinct classes of muscarinic action on hippocampal inhibitory synapses: M2-mediated direct suppression and M1/M3-mediated indirect suppression through endocannabinoid signalling. Eur J Neurosci (2004) 1.71
A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives. Stem Cells (2011) 1.60
Modulation of synaptic plasticity by physiological activation of M1 muscarinic acetylcholine receptors in the mouse hippocampus. J Neurosci (2005) 1.58
Postsynaptic M1 and M3 receptors are responsible for the muscarinic enhancement of retrograde endocannabinoid signalling in the hippocampus. Eur J Neurosci (2003) 1.39
Preferential localization of muscarinic M1 receptor on dendritic shaft and spine of cortical pyramidal cells and its anatomical evidence for volume transmission. J Neurosci (2010) 1.35
Tonic enhancement of endocannabinoid-mediated retrograde suppression of inhibition by cholinergic interneuron activity in the striatum. J Neurosci (2007) 1.19
Input-specific intrasynaptic arrangements of ionotropic glutamate receptors and their impact on postsynaptic responses. J Neurosci (2009) 1.15
M1 receptors mediate cholinergic modulation of excitability in neocortical pyramidal neurons. J Neurosci (2009) 1.15
The M2 muscarinic receptor mediates contraction through indirect mechanisms in mouse urinary bladder. J Pharmacol Exp Ther (2004) 1.14
Estimation of relative microscopic affinity constants of agonists for the active state of the receptor in functional studies on M2 and M3 muscarinic receptors. Mol Pharmacol (2008) 1.11
M(3) muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice. J Physiol (2004) 1.09
Pharmaceutical applications of embryonic stem cells. Adv Drug Deliv Rev (2005) 1.03
Quantitative analysis of binding parameters of [3H]N-methylscopolamine in central nervous system of muscarinic acetylcholine receptor knockout mice. Brain Res Mol Brain Res (2005) 1.02
Combined antagonism of glutamate mGlu5 and adenosine A2A receptors interact to regulate alcohol-seeking in rats. Int J Neuropsychopharmacol (2007) 1.01
Requirement of the immediate early gene vesl-1S/homer-1a for fear memory formation. Mol Brain (2009) 0.99
Effects of muscarinic receptor type 3 knockout on mouse islet secretory responses. Biochem Biophys Res Commun (2004) 0.99
Muscarinic receptor knockout mice confirm involvement of M3 receptor in endothelium-dependent vasodilatation in mouse arteries. J Cardiovasc Pharmacol (2008) 0.97
Comparison between bipolar hemiarthroplasty and THA for osteonecrosis of the femoral head. Clin Orthop Relat Res (2004) 0.96
Pathogenic role of immune response to M3 muscarinic acetylcholine receptor in Sjögren's syndrome-like sialoadenitis. J Autoimmun (2010) 0.94
Cooperative cardioprotection through adenosine A1 and A2A receptor agonism in ischemia-reperfused isolated mouse heart. J Cardiovasc Pharmacol (2010) 0.93
Cystometric findings in mice lacking muscarinic M2 or M3 receptors. J Urol (2004) 0.93
Protein kinase G II-mediated proliferative effects in human cultured prostatic stromal cells. Cell Signal (2004) 0.92
Identification and profiling of novel α1A-adrenoceptor-CXC chemokine receptor 2 heteromer. J Biol Chem (2012) 0.92
Neuronally released acetylcholine acts on the M2 muscarinic receptor to oppose the relaxant effect of isoproterenol on cholinergic contractions in mouse urinary bladder. J Pharmacol Exp Ther (2007) 0.91
Protein kinase G activation of K(ATP) channels in human-cultured prostatic stromal cells. Cell Signal (2002) 0.91
Pharmacological characterisation of a neurotoxin from the venom of Boiga dendrophila (mangrove catsnake). Toxicon (2005) 0.91
Lmx1a allows context-specific isolation of progenitors of GABAergic or dopaminergic neurons during neural differentiation of embryonic stem cells. Stem Cells (2012) 0.90
Investigation of the neuroanatomical substrates of reward seeking following protracted abstinence in mice. J Physiol (2012) 0.90
Alpha1L-adrenoceptors mediate contractions of the isolated mouse prostate. Eur J Pharmacol (2006) 0.87
In vitro maturation of dopaminergic neurons derived from mouse embryonic stem cells: implications for transplantation. PLoS One (2012) 0.86
Characterization of forebrain neurons derived from late-onset Huntington's disease human embryonic stem cell lines. Front Cell Neurosci (2013) 0.86
Cholinergically stimulated gastric acid secretion is mediated by M(3) and M(5) but not M(1) muscarinic acetylcholine receptors in mice. Am J Physiol Gastrointest Liver Physiol (2005) 0.86
Adenosine A(2A) receptors and their role in drug addiction. J Pharm Pharmacol (2008) 0.85
Impaired gastric secretion and lack of trophic responses to hypergastrinemia in M3 muscarinic receptor knockout mice. Gastroenterology (2003) 0.85
Alternative poly(A) site-selection regulates the production of alternatively spliced vesl-1/homer1 isoforms that encode postsynaptic scaffolding proteins. Neurosci Res (2006) 0.85
Opposing functions of spinal M2, M3, and M4 receptor subtypes in regulation of GABAergic inputs to dorsal horn neurons revealed by muscarinic receptor knockout mice. Mol Pharmacol (2005) 0.85
Extended periods of neural induction and propagation of embryonic stem cell-derived neural progenitors with EGF and FGF2 enhances Lmx1a expression and neurogenic potential. Neurochem Int (2011) 0.84
Male contraception via simultaneous knockout of α1A-adrenoceptors and P2X1-purinoceptors in mice. Proc Natl Acad Sci U S A (2013) 0.84
Muscarinic agonist-mediated heterologous desensitization in isolated ileum requires activation of both muscarinic M2 and M3 receptors. J Pharmacol Exp Ther (2003) 0.84
Evaluation of the mouse prostate as a suitable model for the study of human prostate function. J Pharmacol Toxicol Methods (2004) 0.84
A novel highly selective adenosine A1 receptor agonist VCP28 reduces ischemia injury in a cardiac cell line and ischemia-reperfusion injury in isolated rat hearts at concentrations that do not affect heart rate. J Cardiovasc Pharmacol (2010) 0.83
Quantitative analysis of the loss of muscarinic receptors in various peripheral tissues in M1-M5 receptor single knockout mice. Br J Pharmacol (2009) 0.83
Up-regulated PAR-2-mediated salivary secretion in mice deficient in muscarinic acetylcholine receptor subtypes. J Pharmacol Exp Ther (2006) 0.83
Age-related changes in the innervation of the prostate gland: implications for prostate cancer initiation and progression. Organogenesis (2013) 0.82
Extracts of bark from the traditional Chinese herb Phellodendron amurense inhibit contractility of the isolated rat prostate gland. J Ethnopharmacol (2009) 0.81
Adenosine 5'-triphosphate and noradrenaline are excitatory cotransmitters to the fibromuscular stroma of the guinea pig prostate gland. Eur J Pharmacol (2004) 0.81
Heterogeneous population of dopaminergic neurons derived from mouse embryonic stem cells: preliminary phenotyping based on receptor expression and function. Eur J Neurosci (2007) 0.81
Roles of M2 and M4 muscarinic receptors in regulating acetylcholine release from myenteric neurons of mouse ileum. J Neurophysiol (2004) 0.81
Autoimmunity against M₂muscarinic acetylcholine receptor induces myocarditis and leads to a dilated cardiomyopathy-like phenotype. Eur J Immunol (2012) 0.81
Altered brain uptake of therapeutics in a triple transgenic mouse model of Alzheimer's disease. Pharm Res (2013) 0.80
Loss of anti-cataleptic effect of scopolamine in mice lacking muscarinic acetylcholine receptor subtype 4. Eur J Pharmacol (2003) 0.80
Drug access to the central nervous system in Alzheimer's disease: preclinical and clinical insights. Pharm Res (2014) 0.80
The residual nonadrenergic contractile response to nerve stimulation of the mouse prostate is mediated by acetylcholine but not ATP in a comparison with the mouse vas deferens. J Pharmacol Exp Ther (2010) 0.80
Differential coupling of muscarinic M1, M2, and M3 receptors to phosphoinositide hydrolysis in urinary bladder and longitudinal muscle of the ileum of the mouse. J Pharmacol Exp Ther (2006) 0.80
Diminished antigen-specific IgG1 and interleukin-6 production and acetylcholinesterase expression in combined M1 and M5 muscarinic acetylcholine receptor knockout mice. J Neuroimmunol (2007) 0.79
Directed expression of Gata2, Mash1, and Foxa2 synergize to induce the serotonergic neuron phenotype during in vitro differentiation of embryonic stem cells. Stem Cells (2011) 0.79
Enhanced lithium-induced brain recovery following cranial irradiation is not impeded by inflammation. Stem Cells Transl Med (2012) 0.79
Synthesis and biological evaluation of N-substituted noscapine analogues. ChemMedChem (2012) 0.79
CB2 receptor agonism reverses MK-801-induced disruptions of prepulse inhibition in mice. Psychopharmacology (Berl) (2014) 0.79
Current models of human prostate contractility. Clin Exp Pharmacol Physiol (2005) 0.78
Ethanol extracts of saw palmetto contain the indirectly acting sympathomimetic: tyramine. Prostate (2011) 0.78
Phosphorylation of the PKG substrate, vasodilator-stimulated phosphoprotein (VASP), in human cultured prostatic stromal cells. Nitric Oxide (2006) 0.78
The crucial roles of IFN-γ in the development of M3 muscarinic acetylcholine receptor induced Sjögren's syndrome-like sialadenitis. Mod Rheumatol (2012) 0.78
Characterisation of the prostanoid receptor mediating inhibition of smooth muscle contractility in the rat prostate gland. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.78
The guinea pig ileum lacks the direct, high-potency, M(2)-muscarinic, contractile mechanism characteristic of the mouse ileum. Naunyn Schmiedebergs Arch Pharmacol (2009) 0.77
Development of a P2X1-purinoceptor mediated contractile response in the aged mouse prostate gland through slowing down of ATP breakdown. Neurourol Urodyn (2013) 0.77
The synthesis and biological evaluation of multifunctionalised derivatives of noscapine as cytotoxic agents. ChemMedChem (2013) 0.77
Comparison of muscarinic receptor selectivity of solifenacin and oxybutynin in the bladder and submandibular gland of muscarinic receptor knockout mice. Eur J Pharmacol (2009) 0.77
Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous administration in rats. Mol Pharm (2015) 0.77
Targeted disruption of the A2A adenosine receptor reduces in-vitro prostate contractility in mature mice. Eur J Pharmacol (2008) 0.76
Androgens regulate adenylate cyclase activity and intracellular calcium in stromal cells derived from human prostate. Prostate (2010) 0.76
Identification of muscarinic receptor subtypes involved in catecholamine secretion in adrenal medullary chromaffin cells by genetic deletion. Br J Pharmacol (2015) 0.76
M2 and M3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum: Findings obtained with muscarinic-receptor knockout mouse. Am J Physiol Gastrointest Liver Physiol (2006) 0.76
Distinct roles of M1 and M3 muscarinic acetylcholine receptors controlling oscillatory and non-oscillatory [Ca2+]i increase. Cell Calcium (2013) 0.76
Memantine transport across the mouse blood-brain barrier is mediated by a cationic influx H+ antiporter. Mol Pharm (2013) 0.76
Does the autonomic nervous system contribute to the initiation and progression of prostate cancer? Asian J Androl (2013) 0.76
M3 muscarinic acetylcholine receptor reactive IL-17 producing T cells promotes development of Sjögren's syndrome like sialadenitis. Mod Rheumatol (2014) 0.76
DNA-dependent protein kinase is a context dependent regulator of Lmx1a and midbrain specification. PLoS One (2013) 0.75
Protein kinase C and the sub-sensitivity and sub-reactivity of the diabetic rat prostate gland to noradrenaline. Eur J Pharmacol (2002) 0.75
Extracellular Ca(2+) entry and mobilization of inositol trisphosphate-dependent Ca(2+) stores modulate histamine and electrical field stimulation induced contractions of the guinea-pig prostate. Pharmacol Res (2011) 0.75
The effects of targeted deletion of the aromatase enzyme on prostatic contractile responses to noradrenaline in mice. J Endocrinol (2007) 0.75
Measurement of postvoid residual urine in conscious mice using high-frequency transrectal ultrasound. Ultrasound Med Biol (2012) 0.75
Saw palmetto is an indirectly acting sympathomimetic in the rat-isolated prostate gland. Prostate (2006) 0.75
Functional characterization on invertebrate and vertebrate tissues of tachykinin peptides from octopus venoms. Peptides (2013) 0.75
Troubleshooting immunohistochemical labelling of proliferating cell nuclear antigen (PCNA) in cryocut tissue sections of mouse prostate. J Pharmacol Toxicol Methods (2009) 0.75
Reduced CNS exposure of memantine in a triple transgenic mouse model of Alzheimer's disease assessed using a novel LC-MS technique. J Pharm Biomed Anal (2013) 0.75
Synthesis and pharmacological evaluation of dual acting antioxidant A(2A) adenosine receptor agonists. J Med Chem (2012) 0.75
Role of immune response to M3 muscarinic acethylcholine receptor in the pathogenesis of Sjögren's syndrome. Nihon Rinsho Meneki Gakkai Kaishi (2010) 0.75
Rho kinase activation mediates adrenergic and cholinergic smooth muscle contractile responses in the mouse prostate gland. Eur J Pharmacol (2013) 0.75