The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases.

PubWeight™: 1.00‹?› | Rank: Top 15%

🔗 View Article (PMID 26928935)

Published in Nat Chem Biol on February 29, 2016

Authors

Kristian E H Frandsen1, Thomas J Simmons2, Paul Dupree3, Jens-Christian N Poulsen1, Glyn R Hemsworth4, Luisa Ciano4, Esther M Johnston4, Morten Tovborg5, Katja S Johansen5, Pernille von Freiesleben5, Laurence Marmuse6, Sébastien Fort6, Sylvain Cottaz6, Hugues Driguez6, Bernard Henrissat7,8,9, Nicolas Lenfant7,8, Floriana Tuna10, Amgalanbaatar Baldansuren10, Gideon J Davies4, Leila Lo Leggio1, Paul H Walton4

Author Affiliations

1: Department of Chemistry, University of Copenhagen, Copenhagen, Denmark.
2: Department of Biochemistry, University of Cambridge, Cambridge, UK.
3: Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, United Kingdom (N.N., P.V.S., L.G., P.D., K.S.L.); Computational Proteomics Unit (L.G.), and Cambridge Centre for Proteomics, Cambridge Systems Biology Centre (N.N., P.S., L.G., K.L.), Department of Biochemistry, University of Cambridge, Cambridge CB2 1QR, United Kingdom pd101@cam.ac.uk k.s.lilley@bioc.cam.ac.uk.
4: Department of Chemistry, University of York, York, UK.
5: Novozymes A/S, Bagsvaerd, Denmark.
6: Centre de Recherches sur les Macromolecules Végétales (CERMAV), Université de Grenoble Alpes, Centre National de la Recherche Scientifique (CNRS), Grenoble, France.
7: Architecture et Fonction des Macromolécules Biologiques (AFMB), CNRS, Aix-Marseille Université, Marseille, France.
8: Institut National de la Recherche Agronomique (INRA), AFMB, Marseille, France.
9: Department of Biological Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
10: Engineering and Physical Sciences Research Council (EPSRC) National EPR Facility, School of Chemistry and Photon Science Institute, University of Manchester, Manchester, UK.

Articles citing this

Lytic polysaccharide monooxygenases disrupt the cellulose fibers structure. Sci Rep (2017) 0.80

Interactions of a fungal lytic polysaccharide monooxygenase with β-glucan substrates and cellobiose dehydrogenase. Proc Natl Acad Sci U S A (2016) 0.79

Heterogeneity in the Histidine-brace Copper Coordination Sphere in Auxiliary Activity Family 10 (AA10) Lytic Polysaccharide Monooxygenases. J Biol Chem (2016) 0.78

Oxygen Activation at the Active Site of a Fungal Lytic Polysaccharide Monooxygenase. Angew Chem Int Ed Engl (2016) 0.78

Lytic polysaccharide monooxygenases from Myceliophthora thermophila C1 differ in substrate preference and reducing agent specificity. Biotechnol Biofuels (2016) 0.77

Oxidative cleavage of polysaccharides by monocopper enzymes depends on H2O2. Nat Chem Biol (2017) 0.77

A tale of two methane monooxygenases. J Biol Inorg Chem (2016) 0.75

The Podospora anserina lytic polysaccharide monooxygenase PaLPMO9H catalyzes oxidative cleavage of diverse plant cell wall matrix glycans. Biotechnol Biofuels (2017) 0.75

Deciphering the Regulatory Network between the SREBP Pathway and Protein Secretion in Neurospora crassa. MBio (2017) 0.75

Lytic polysaccharide monooxygenases: a crystallographer's view on a new class of biomass-degrading enzymes. IUCrJ (2016) 0.75

The Role of the Secondary Coordination Sphere in a Fungal Polysaccharide Monooxygenase. ACS Chem Biol (2017) 0.75

Interdomain flip-flop motion visualized in flavocytochrome cellobiose dehydrogenase using high-speed atomic force microscopy during catalysis. Chem Sci (2017) 0.75

Targeting the reactive intermediate in polysaccharide monooxygenases. J Biol Inorg Chem (2017) 0.75

The yeast Geotrichum candidum encodes functional lytic polysaccharide monooxygenases. Biotechnol Biofuels (2017) 0.75

Single-molecule study of oxidative enzymatic deconstruction of cellulose. Nat Commun (2017) 0.75

A quantitative indicator diagram for lytic polysaccharide monooxygenases reveals the role of aromatic surface residues in HjLPMO9A regioselectivity. PLoS One (2017) 0.75

Articles cited by this

Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01

XDS. Acta Crystallogr D Biol Crystallogr (2010) 67.46

The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res (2008) 27.83

Molecular replacement with MOLREP. Acta Crystallogr D Biol Crystallogr (2009) 26.26

REFMAC5 dictionary: organization of prior chemical knowledge and guidelines for its use. Acta Crystallogr D Biol Crystallogr (2004) 14.28

Biomass recalcitrance: engineering plants and enzymes for biofuels production. Science (2007) 11.75

The carbohydrate-active enzymes database (CAZy) in 2013. Nucleic Acids Res (2013) 10.24

Stimulation of lignocellulosic biomass hydrolysis by proteins of glycoside hydrolase family 61: structure and function of a large, enigmatic family. Biochemistry (2010) 3.70

Insights into the oxidative degradation of cellulose by a copper metalloenzyme that exploits biomass components. Proc Natl Acad Sci U S A (2011) 3.59

An oxidative enzyme boosting the enzymatic conversion of recalcitrant polysaccharides. Science (2010) 3.43

Novel enzymes for the degradation of cellulose. Biotechnol Biofuels (2012) 2.85

Progress and challenges in enzyme development for biomass utilization. Adv Biochem Eng Biotechnol (2007) 2.82

Cellobiose dehydrogenase and a copper-dependent polysaccharide monooxygenase potentiate cellulose degradation by Neurospora crassa. ACS Chem Biol (2011) 2.76

Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases. Structure (2012) 2.51

Cleavage of cellulose by a CBM33 protein. Protein Sci (2011) 2.38

Discovery and characterization of a new family of lytic polysaccharide monooxygenases. Nat Chem Biol (2013) 1.53

Recent insights into copper-containing lytic polysaccharide mono-oxygenases. Curr Opin Struct Biol (2013) 1.50

Discovery of LPMO activity on hemicelluloses shows the importance of oxidative processes in plant cell wall degradation. Proc Natl Acad Sci U S A (2014) 1.46

NMR structure of a lytic polysaccharide monooxygenase provides insight into copper binding, protein dynamics, and substrate interactions. Proc Natl Acad Sci U S A (2012) 1.46

A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme. Proc Natl Acad Sci U S A (2005) 1.45

Carbohydrate-aromatic interactions. Acc Chem Res (2012) 1.35

Crystal structure and computational characterization of the lytic polysaccharide monooxygenase GH61D from the Basidiomycota fungus Phanerochaete chrysosporium. J Biol Chem (2013) 1.34

Use of a fluorescence plate reader for measuring kinetic parameters with inner filter effect correction. Anal Biochem (1999) 1.28

Rapid C-H bond activation by a monocopper(III)-hydroxide complex. J Am Chem Soc (2011) 1.27

Quantum mechanical calculations suggest that lytic polysaccharide monooxygenases use a copper-oxyl, oxygen-rebound mechanism. Proc Natl Acad Sci U S A (2013) 1.25

The copper active site of CBM33 polysaccharide oxygenases. J Am Chem Soc (2013) 1.23

Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase. Nat Commun (2015) 1.18

Oxidation: an important enzyme reaction in fungal degradation of cellulose. FEBS Lett (1974) 1.18

Stereoelectronic effects of deoxyribose O4' on DNA conformation. Proc Natl Acad Sci U S A (1995) 1.14

Conformational analyses of the reaction coordinate of glycosidases. Acc Chem Res (2011) 1.11

Cellulose degradation by polysaccharide monooxygenases. Annu Rev Biochem (2015) 1.11

Fungal cellulases. Chem Rev (2015) 1.08

Spectroscopic and computational insight into the activation of O2 by the mononuclear Cu center in polysaccharide monooxygenases. Proc Natl Acad Sci U S A (2014) 1.08

Substrate specificity and regioselectivity of fungal AA9 lytic polysaccharide monooxygenases secreted by Podospora anserina. Biotechnol Biofuels (2015) 1.06

The CH/π hydrogen bond in chemistry. Conformation, supramolecules, optical resolution and interactions involving carbohydrates. Phys Chem Chem Phys (2011) 1.03

Harnessing the potential of LPMO-containing cellulase cocktails poses new demands on processing conditions. Biotechnol Biofuels (2015) 0.98

Structural and electronic snapshots during the transition from a Cu(II) to Cu(I) metal center of a lytic polysaccharide monooxygenase by X-ray photoreduction. J Biol Chem (2014) 0.95

A rapid quantitative activity assay shows that the Vibrio cholerae colonization factor GbpA is an active lytic polysaccharide monooxygenase. FEBS Lett (2014) 0.94

Structural and Functional Characterization of a Lytic Polysaccharide Monooxygenase with Broad Substrate Specificity. J Biol Chem (2015) 0.93

Hydrogen atom abstraction from hydrocarbons by a copper(III)-hydroxide complex. J Am Chem Soc (2015) 0.92

Biomimetic reagents for the selective free radical and acid-base chemistry of glycans: application to glycan structure determination by mass spectrometry. J Am Chem Soc (2013) 0.91

Elaboration of copper-oxygen mediated C-H activation chemistry in consideration of future fuel and feedstock generation. Curr Opin Chem Biol (2015) 0.86

The n → π* interaction: a rapidly emerging non-covalent interaction. Phys Chem Chem Phys (2015) 0.83

34 GHz pulsed ENDOR characterization of the copper coordination of an amyloid β peptide relevant to Alzheimer's disease. Angew Chem Int Ed Engl (2012) 0.82

Noncovalent Lone Pair⋅⋅⋅(No-π!)-Heteroarene Interactions: The Janus-Faced Hydroxy Group. Angew Chem Int Ed Engl (2015) 0.77

Articles by these authors

Structural characterization of human heparanase reveals insights into substrate recognition. Nat Struct Mol Biol (2015) 1.48

Privateer: software for the conformational validation of carbohydrate structures. Nat Struct Mol Biol (2015) 1.07

Label-free protein quantification for plant Golgi protein localization and abundance. Plant Physiol (2014) 0.83

Aspen Tension Wood Fibers Contain β-(1→4)-Galactans and Acidic Arabinogalactans Retained by Cellulose Microfibrils in Gelatinous Walls. Plant Physiol (2015) 0.81

Structural and functional insight into human O-GlcNAcase. Nat Chem Biol (2017) 0.80

Golgi-localized STELLO proteins regulate the assembly and trafficking of cellulose synthase complexes in Arabidopsis. Nat Commun (2016) 0.78

Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors. J Am Chem Soc (2017) 0.76

Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut. Open Biol (2016) 0.75

Folding of xylan onto cellulose fibrils in plant cell walls revealed by solid-state NMR. Nat Commun (2016) 0.75

Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates. Nat Commun (2017) 0.75

Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines. Chem Commun (Camb) (2017) 0.75

Conformational Analysis of the Mannosidase Inhibitor Kifunensine: A Quantum Mechanical and Structural Approach. Chembiochem (2017) 0.75

Intermediate-spin iron(IV)-oxido species with record reactivity. Faraday Discuss (2022) 0.75

Discovery of α-L-arabinopyranosidases from human gut microbiome expands the diversity within glycoside hydrolase family 42. J Biol Chem (2017) 0.75

Activity-based probes for functional interrogation of retaining β-glucuronidases. Nat Chem Biol (2017) 0.75

Activity and substrate specificity of lytic polysaccharide monooxygenases: An ATR FTIR-based sensitive assay tested on a novel species from Pseudomonas putida. Protein Sci (2021) 0.75

A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase. J Am Chem Soc (2017) 0.75

An atypical interaction explains the high-affinity of a non-hydrolyzable S-linked 1,6-α-mannanase inhibitor. Chem Commun (Camb) (2017) 0.75

Oxidoreductases on their way to industrial biotransformations. Biotechnol Adv (2017) 0.75

An even pattern of xylan substitution is critical for interaction with cellulose in plant cell walls. Nat Plants (2017) 0.75