NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.

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Published in Nature on March 02, 2016

Authors

Chi Ma1, Aparna H Kesarwala2, Tobias Eggert1, José Medina-Echeverz1, David E Kleiner3, Ping Jin4, David F Stroncek4, Masaki Terabe5, Veena Kapoor6, Mei ElGindi1, Miaojun Han1, Angela M Thornton7, Haibo Zhang8, Michèle Egger9, Ji Luo8, Dean W Felsher10, Daniel W McVicar11, Achim Weber9, Mathias Heikenwalder12,13, Tim F Greten1

Author Affiliations

1: Gastrointestinal Malignancy Section, Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
2: Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
3: Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
4: Cell Processing Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, USA.
5: Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
6: Experimental Transplantation and Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
7: Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
8: Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
9: Institute of Surgical Pathology, University and University Hospital Zurich, Zurich 8091, Switzerland.
10: Division of Oncology, Department of Medicine and Pathology, Stanford University, California 94305, USA.
11: Cancer and Inflammation Program, National Cancer Institute, Frederick, Maryland 21702, USA.
12: Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich 81675, Germany.
13: Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany.

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