Interplay between Cellular and Molecular Inflammatory Mediators in Lung Cancer.

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Published in Mediators Inflamm on January 28, 2016

Authors

Mario Orozco-Morales1, Giovanny Soca-Chafre1, Pedro Barrios-Bernal1, Norma Hernández-Pedro1, Oscar Arrieta2

Author Affiliations

1: Experimental Oncology Laboratory, National Cancer Institute of Mexico (INCan), 14080 Mexico, DF, Mexico.
2: Experimental Oncology Laboratory, National Cancer Institute of Mexico (INCan), 14080 Mexico, DF, Mexico; Thoracic Oncology Unit, National Cancer Institute of Mexico (INCan), 14080 Mexico, DF, Mexico.

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Global cancer statistics. CA Cancer J Clin (2011) 185.92

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Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A (2013) 16.74

Lung cancer. N Engl J Med (2008) 13.49

Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med (2009) 13.47

Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst (2005) 13.00

Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer. N Engl J Med (2015) 12.54

Resolution of inflammation: the beginning programs the end. Nat Immunol (2005) 9.81

The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol (2002) 8.27

Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN. Cancer Cell (2009) 8.21

Role of CD47 as a marker of self on red blood cells. Science (2000) 7.00

Lung cancer in never smokers--a different disease. Nat Rev Cancer (2007) 6.41

Corpse clearance defines the meaning of cell death. Nature (2000) 6.01

Macrophage polarization comes of age. Immunity (2005) 5.67

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell (2009) 5.30

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell (2009) 5.22

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Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci U S A (2009) 3.87

International lung cancer trends by histologic type: male:female differences diminishing and adenocarcinoma rates rising. Int J Cancer (2005) 3.81

Integrin-associated protein (CD47) and its ligands. Trends Cell Biol (2001) 3.79

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New vistas on macrophage differentiation and activation. Eur J Immunol (2007) 2.99

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CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis. J Exp Med (2001) 2.75

Decreased resistance to bacterial infection and granulocyte defects in IAP-deficient mice. Science (1996) 2.55

Phagocytosis and innate immunity. Curr Opin Immunol (2002) 2.47

Pathology of lung cancer. Clin Chest Med (2011) 2.40

Inhibition of "self" engulfment through deactivation of myosin-II at the phagocytic synapse between human cells. J Cell Biol (2008) 2.39

Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms. J Immunol (2008) 2.26

Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo. J Exp Med (1991) 2.11

Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3-dependent ligand binding. J Cell Biol (1993) 2.10

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Tumour-associated macrophages (TAMS): disordered function, immune suppression and progressive tumour growth. J R Coll Surg Edinb (2000) 1.09

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Technical advance: immunophenotypical characterization of human neutrophil differentiation. J Leukoc Biol (2011) 0.85

Inflammation-induced proteolytic processing of the SIRPα cytoplasmic ITIM in neutrophils propagates a proinflammatory state. Nat Commun (2013) 0.85

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Lung carcinomas decrease the number of monocytes/macrophages (CD14+ cells) that produce TNF-alpha. Clin Immunol (2006) 0.83

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