Published in Ups J Med Sci on March 08, 2016
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Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: implications for intrahepatic grafts. J Leukoc Biol (2005) 2.00
Cotransplantation of Polymerized Hemoglobin Reduces β-Cell Hypoxia and Improves β-Cell Function in Intramuscular Islet Grafts. Transplantation (2015) 1.41
Amelioration of diabetes by imatinib mesylate (Gleevec): role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning. FASEB J (2006) 1.29
Rapid deposition of amyloid in human islets transplanted into nude mice. Diabetologia (1995) 1.23
Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets. Diabetes (2008) 1.17
Human pancreatic beta-cell deoxyribonucleic acid-synthesis in islet grafts decreases with increasing organ donor age but increases in response to glucose stimulation in vitro. Endocrinology (1996) 1.16
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Impairment of glucose-induced insulin secretion in human pancreatic islets transplanted to diabetic nude mice. J Clin Invest (1995) 1.08
Abrogation of the cell death response to oxidative stress by the c-Abl tyrosine kinase inhibitor STI571. Mol Pharmacol (2003) 1.07
Better vascular engraftment and function in pancreatic islets transplanted without prior culture. Diabetologia (2005) 1.06
Islet transplantation outcomes in mice are better with fresh islets and exendin-4 treatment. Diabetologia (2005) 1.01
Effects of glucose and amino acids on the biosynthesis of DNA and insulin in fetal rat islets maintained in tissue culture. Diabetes (1980) 1.00
Imatinib mesylate (Gleevec) protects against streptozotocin-induced diabetes and islet cell death in vitro. Cell Biol Int (2006) 1.00
Ductal injection of JNK inhibitors before pancreas preservation prevents islet apoptosis and improves islet graft function. Hum Gene Ther (2009) 0.92
c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. J Biol Chem (2005) 0.90
Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function. Am J Transplant (2005) 0.89
Potential utility of small tyrosine kinase inhibitors in the treatment of diabetes. Clin Sci (Lond) (2009) 0.89
Imatinib mesylate improves insulin sensitivity and glucose disposal rates in rats fed a high-fat diet. Clin Sci (Lond) (2008) 0.89
Choosing between growth arrest and apoptosis through the retinoblastoma tumour suppressor protein, Abl and p73. Biochem Soc Trans (2001) 0.89
Pre-culturing islets with mesenchymal stromal cells using a direct contact configuration is beneficial for transplantation outcome in diabetic mice. Cytotherapy (2013) 0.88
Donor pretreatment with DHMEQ improves islet transplantation. J Surg Res (2010) 0.88
No differences in efficacy between noncultured and cultured islets in reducing hyperglycemia in a nonvascularized islet graft model. Diabetes Technol Ther (2006) 0.88
Role of zinc and calcium in the formation and storage of insulin in the pancreatic beta-cell. Cell Tissue Res (1978) 0.87
Improved intraportal islet transplantation outcome by systemic IKK-beta inhibition: NF-κB activity in pancreatic islets depends on oxygen availability. Am J Transplant (2011) 0.86
Inhibition of c-Abl with STI571 attenuates stress-activated protein kinase activation and apoptosis in the cellular response to 1-beta-D-arabinofuranosylcytosine. Mol Pharmacol (2002) 0.86
Conditional and specific inhibition of NF-κB in mouse pancreatic β cells prevents cytokine-induced deleterious effects and improves islet survival posttransplant. Surgery (2011) 0.86
Co-transplantation of islets with mesenchymal stem cells in microcapsules demonstrates graft outcome can be improved in an isolated-graft model of islet transplantation in mice. Cytotherapy (2013) 0.86
Nano-scale encapsulation enhances allograft survival and function of islets transplanted in a mouse model of diabetes. Diabetologia (2012) 0.85
Radioautographic localization of labelled proteins after incubation of guinea-pig islets of Langerhans with (3H)tryptophan. Biochem J (1974) 0.83
Annexin A1 Is a Key Modulator of Mesenchymal Stromal Cell-Mediated Improvements in Islet Function. Diabetes (2015) 0.82
Maintenance of islet morphology is beneficial for transplantation outcome in diabetic mice. PLoS One (2013) 0.82
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Mechanisms of defective glucose-induced insulin release in human pancreatic islets transplanted to diabetic nude mice. J Clin Endocrinol Metab (1997) 0.82
Imatinib mesilate-induced phosphatidylinositol 3-kinase signalling and improved survival in insulin-producing cells: role of Src homology 2-containing inositol 5'-phosphatase interaction with c-Abl. Diabetologia (2013) 0.81
Engraftment and growth of transplanted pancreatic islets. Ups J Med Sci (2000) 0.81
Assessment of insulin secretion in vitro from microencapsulated fetal porcine islet-like cell clusters and rat, mouse, and human pancreatic islets. Transplantation (1997) 0.81
Islet alpha cell number is maintained in microencapsulated islet transplantation. Biochem Biophys Res Commun (2008) 0.80
Effects of Imatinib Mesylate (Gleevec) on human islet NF-kappaB activation and chemokine production in vitro. PLoS One (2011) 0.80
Transient beneficial effects of exendin-4 treatment on the function of microencapsulated mouse pancreatic islets. Cell Transplant (2007) 0.79
Non-receptor tyrosine kinase inhibitors enhances β-cell survival by suppressing the PKCδ signal transduction pathway in streptozotocin-induced β-cell apoptosis. Cell Signal (2015) 0.79
Imaging the islet graft by positron emission tomography. Eur J Nucl Med Mol Imaging (2011) 0.79
Structure and function of macroencapsulated human and rodent pancreatic islets transplanted into nude mice. Horm Metab Res (1996) 0.78
Glucose metabolism in vitro of cultured and transplanted mouse pancreatic islets microencapsulated by means of a high-voltage electrostatic field. Diabetes Care (1999) 0.78
The sequential combination of a JNK inhibitor and simvastatin protects porcine islets from peritransplant apoptosis and inflammation. Cell Transplant (2010) 0.77
Preculturing Islets With Adipose-Derived Mesenchymal Stromal Cells Is an Effective Strategy for Improving Transplantation Efficiency at the Clinically Preferred Intraportal Site. Cell Med (2014) 0.77
Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells. Clin Sci (Lond) (2015) 0.77
STI571 protects neuronal cells from neurotoxic prion protein fragment-induced apoptosis. Neuropharmacology (2015) 0.76
Assembly of bioactive multilayered nanocoatings on pancreatic islet cells: incorporation of α1-antitrypsin into the coatings. Chem Commun (Camb) (2015) 0.76
Intracellular transport and storage of newly synthesised proteins in the guinea pig pancreatic A cell. Horm Metab Res (1974) 0.76
Immunoisolation of islets in high guluronic acid barium-alginate microcapsules does not improve graft outcome at the subcutaneous site. Artif Organs (2012) 0.76
Surface Coating of Pancreatic Islets With Neural Crest Stem Cells Improves Engraftment and Function After Intraportal Transplantation. Cell Transplant (2015) 0.76
Inhibition of c-Kit is not required for reversal of hyperglycemia by imatinib in NOD mice. PLoS One (2014) 0.76
Immunosuppression, macroencapsulation and ultraviolet-B irradiation as immunoprotection in porcine pancreatic islet xenotransplantation. Pharmacol Toxicol (1995) 0.76
ALK5 inhibition maintains islet endothelial cell survival but does not enhance islet graft revascularisation or function. Horm Metab Res (2014) 0.76
Sustained NF-κB activation and inhibition in β-cells have minimal effects on function and islet transplant outcomes. PLoS One (2013) 0.76