Published in Cell Rep on March 10, 2016
Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments. Cell (1990) 9.60
Dendritic cell regulation of TH1-TH2 development. Nat Immunol (2000) 5.13
T-cell engagement of dendritic cells rapidly rearranges MHC class II transport. Nature (2002) 3.93
Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature (2002) 3.21
T cells use two directionally distinct pathways for cytokine secretion. Nat Immunol (2006) 3.01
Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol Rev (2009) 2.89
CD8α(+) dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites. Immunity (2011) 2.50
Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse; involvement of SNARE complexes. Immunity (2004) 2.47
A role for the phagosome in cytokine secretion. Science (2005) 2.45
Inflammatory cytokines as a third signal for T cell activation. Curr Opin Immunol (2010) 2.44
Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event. Nat Immunol (2001) 2.34
Focal exocytosis of VAMP3-containing vesicles at sites of phagosome formation. J Cell Biol (2000) 2.10
VAMP-7 mediates vesicular transport from endosomes to lysosomes. J Cell Biol (1999) 2.01
NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs. Blood (2004) 1.88
Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells. J Cell Biol (2001) 1.87
Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth. J Cell Biol (2000) 1.82
SNAREing immunity: the role of SNAREs in the immune system. Nat Rev Immunol (2006) 1.77
TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways. Biochim Biophys Acta (2009) 1.76
Immunological synapses are versatile structures enabling selective T cell polarization. Immunity (2005) 1.65
Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages. Mol Biol Cell (2000) 1.43
Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking. FEBS Lett (2009) 1.40
Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha. J Biol Chem (2005) 1.39
Cutting edge: dendritic cell actin cytoskeletal polarization during immunological synapse formation is highly antigen-dependent. J Immunol (2003) 1.33
Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFalpha. J Cell Biol (2007) 1.32
VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways. Blood (2008) 1.26
The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion. Curr Biol (2003) 1.22
A molecular network for the transport of the TI-VAMP/VAMP7 vesicles from cell center to periphery. Dev Cell (2012) 1.22
High-resolution dissection of phagosome maturation reveals distinct membrane trafficking phases. Mol Biol Cell (2002) 1.18
Monomeric IgG is neuroprotective via enhancing microglial recycling endocytosis and TNF-alpha. J Neurosci (2008) 1.18
Combinatorial SNARE complexes modulate the secretion of cytoplasmic granules in human neutrophils. J Immunol (2006) 1.16
hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins. Nat Commun (2013) 1.14
Cdc42-mediated MTOC polarization in dendritic cells controls targeted delivery of cytokines at the immune synapse. J Exp Med (2010) 1.13
T cells induce extended class II MHC compartments in dendritic cells in a Toll-like receptor-dependent manner. J Immunol (2003) 1.09
Biosynthesis and posttranslational regulation of human IL-12. J Immunol (2000) 1.09
Cytokine secretion is distinct from secretion of cytotoxic granules in NK cells. J Immunol (2010) 1.07
MHC class II compartments in human dendritic cells undergo profound structural changes upon activation. Traffic (2002) 1.06
Mast cell degranulation requires N-ethylmaleimide-sensitive factor-mediated SNARE disassembly. J Immunol (2003) 1.02
Disparate intracellular processing of human IL-12 preprotein subunits: atypical processing of the P35 signal peptide. J Immunol (2000) 1.02
Spinophilin participates in information transfer at immunological synapses. J Cell Biol (2008) 1.01
A role for Rab7 in the movement of secretory granules in cytotoxic T lymphocytes. Traffic (2011) 0.98
Activation of the ancestral polarity regulator protein kinase C zeta at the immunological synapse drives polarization of Th cell secretory machinery toward APCs. J Immunol (2010) 0.98
VAMP4- and VAMP7-expressing vesicles are both required for cytotoxic granule exocytosis in NK cells. Eur J Immunol (2011) 0.97
Role of TI-VAMP and CD82 in EGFR cell-surface dynamics and signaling. J Cell Sci (2010) 0.96
The exocytosis of lytic granules is impaired in Vti1b- or Vamp8-deficient CTL leading to a reduced cytotoxic activity following antigen-specific activation. J Immunol (2010) 0.94
The dendritic cell cytoskeleton promotes T cell adhesion and activation by constraining ICAM-1 mobility. J Cell Biol (2015) 0.92
Understanding the cell biology of antigen presentation: the dendritic cell contribution. Curr Opin Cell Biol (2003) 0.92
Absence of TI-VAMP/Vamp7 leads to increased anxiety in mice. J Neurosci (2012) 0.91
Synaptobrevin2 is the v-SNARE required for cytotoxic T-lymphocyte lytic granule fusion. Nat Commun (2013) 0.88
The sorting receptor Sortilin exhibits a dual function in exocytic trafficking of interferon-γ and granzyme A in T cells. Immunity (2012) 0.86
A role for syntaxin 3 in the secretion of IL-6 from dendritic cells following activation of toll-like receptors. Front Immunol (2015) 0.84