Published in J Biol Chem on January 07, 2005
NF-kappaB translocation prevents host cell death after low-dose challenge by Legionella pneumophila. J Exp Med (2006) 2.06
Shouts, whispers and the kiss of death: directional secretion in T cells. Nat Immunol (2008) 1.92
A genome-wide association study of autism using the Simons Simplex Collection: Does reducing phenotypic heterogeneity in autism increase genetic homogeneity? Biol Psychiatry (2014) 1.68
Syntaxin 11 is required for NK and CD8⁺ T-cell cytotoxicity and neutrophil degranulation. Eur J Immunol (2012) 1.57
Macrophage cytokines: involvement in immunity and infectious diseases. Front Immunol (2014) 1.44
Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFalpha. J Cell Biol (2007) 1.32
Rab8 regulates basolateral secretory, but not recycling, traffic at the recycling endosome. Mol Biol Cell (2008) 1.32
A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo. Proc Natl Acad Sci U S A (2008) 1.24
Epimorphin(-/-) mice have increased intestinal growth, decreased susceptibility to dextran sodium sulfate colitis, and impaired spermatogenesis. J Clin Invest (2006) 1.11
Human NK cell lytic granules and regulation of their exocytosis. Front Immunol (2012) 1.10
Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretion. J Cell Biol (2010) 1.03
Syntaxin 16 binds to cystic fibrosis transmembrane conductance regulator and regulates its membrane trafficking in epithelial cells. J Biol Chem (2010) 1.01
The SNARE Machinery in Mast Cell Secretion. Front Immunol (2012) 0.98
Fatty acid-binding protein E-FABP restricts tumor growth by promoting IFN-β responses in tumor-associated macrophages. Cancer Res (2014) 0.98
Regulation of integrin endocytic recycling and chemotactic cell migration by syntaxin 6 and VAMP3 interaction. J Cell Sci (2012) 0.98
Recycling of IRAP from the plasma membrane back to the insulin-responsive compartment requires the Q-SNARE syntaxin 6 but not the GGA clathrin adaptors. J Cell Sci (2008) 0.95
Vesicular trafficking and signaling for cytokine and chemokine secretion in mast cells. Front Immunol (2014) 0.94
Regulation of intracellular membrane trafficking and cell dynamics by syntaxin-6. Biosci Rep (2012) 0.88
Cytokine Secretion in Macrophages: SNAREs, Rabs, and Membrane Trafficking. Front Immunol (2014) 0.88
RAB8 enhances TMEM205-mediated cisplatin resistance. Pharm Res (2011) 0.87
Characterization of SNAREs determines the absence of a typical Golgi apparatus in the ancient eukaryote Giardia lamblia. J Biol Chem (2008) 0.86
Salmonella acquires lysosome-associated membrane protein 1 (LAMP1) on phagosomes from Golgi via SipC protein-mediated recruitment of host Syntaxin6. J Biol Chem (2011) 0.85
Rab6a/a' are important Golgi regulators of pro-inflammatory TNF secretion in macrophages. PLoS One (2013) 0.84
Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages. Mol Biol Cell (2015) 0.84
A role for syntaxin 3 in the secretion of IL-6 from dendritic cells following activation of toll-like receptors. Front Immunol (2015) 0.84
An Emerging Role for SNARE Proteins in Dendritic Cell Function. Front Immunol (2015) 0.84
Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45. Mol Biol Cell (2013) 0.83
Regulation of the endosomal SNARE protein syntaxin 7 by colony-stimulating factor 1 in macrophages. Mol Cell Biol (2008) 0.81
The differentiation/retrodifferentiation program of human U937 leukemia cells is accompanied by changes of VCP/p97. BMC Cell Biol (2008) 0.81
Spleen tyrosine kinase (Syk)-dependent calcium signals mediate efficient CpG-induced exocytosis of tumor necrosis factor α (TNFα) in innate immune cells. J Biol Chem (2013) 0.81
Endosome-mediated autophagy: an unconventional MIIC-driven autophagic pathway operational in dendritic cells. Autophagy (2013) 0.80
An essential role of syntaxin 3 protein for granule exocytosis and secretion of IL-1α, IL-1β, IL-12b, and CCL4 from differentiated HL-60 cells. J Leukoc Biol (2014) 0.80
Innate immunity and exocytosis of antimicrobial peptides. Commun Integr Biol (2012) 0.79
Oxidized phagosomal NOX2 complex is replenished from lysosomes. J Cell Sci (2017) 0.78
The role of the recycling endosome in regulating lamellipodia formation and macrophage migration. Commun Integr Biol (2011) 0.78
Genome-wide profiling of in vivo LPS-responsive genes in splenic myeloid cells. Mol Cells (2013) 0.76
The SNARE VAMP7 Regulates Exocytic Trafficking of Interleukin-12 in Dendritic Cells. Cell Rep (2016) 0.76
The STX6-VTI1B-VAMP3 complex facilitates xenophagy by regulating the fusion between recycling endosomes and autophagosomes. Autophagy (2016) 0.76
GPX-Macrophage Expression Atlas: a database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insults. BMC Genomics (2005) 0.75
Small GTPase Rab8a-recruited Phosphatidylinositol 3-Kinase γ Regulates Signaling and Cytokine Outputs from Endosomal Toll-like Receptors. J Biol Chem (2017) 0.75
Kelch-like Protein 21 (KLHL21) Targets IκB Kinase-β to Regulate Nuclear Factor κ-Light Chain Enhancer of Activated B Cells (NF-κB) Signaling Negatively. J Biol Chem (2016) 0.75
Recycling endosomes in human cytotoxic T lymphocytes constitute an auxiliary intracellular trafficking pathway for newly synthesized perforin. Immunol Res (2017) 0.75
Genome-wide analysis of mammalian promoter architecture and evolution. Nat Genet (2006) 17.19
Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol (2003) 12.34
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science (2009) 6.59
A promoter-level mammalian expression atlas. Nature (2014) 6.25
An atlas of combinatorial transcriptional regulation in mouse and man. Cell (2010) 6.24
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity (2012) 6.18
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet (2009) 6.02
The regulated retrotransposon transcriptome of mammalian cells. Nat Genet (2009) 5.79
Mammalian RNA polymerase II core promoters: insights from genome-wide studies. Nat Rev Genet (2007) 5.75
Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome. Genome Res (2005) 4.86
IFITM3 restricts the morbidity and mortality associated with influenza. Nature (2012) 4.66
Unravelling mononuclear phagocyte heterogeneity. Nat Rev Immunol (2010) 4.25
Tiny RNAs associated with transcription start sites in animals. Nat Genet (2009) 4.19
Somatic retrotransposition alters the genetic landscape of the human brain. Nature (2011) 4.16
A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood (2002) 4.06
Expression analysis of G Protein-Coupled Receptors in mouse macrophages. Immunome Res (2008) 3.54
Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. Genome Res (2003) 3.50
Impact of alternative initiation, splicing, and termination on the diversity of the mRNA transcripts encoded by the mouse transcriptome. Genome Res (2003) 3.21
A rescue strategy for multimapping short sequence tags refines surveys of transcriptional activity by CAGE. Genomics (2008) 3.19
CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation. J Exp Med (2009) 3.07
Rab11 in recycling endosomes regulates the sorting and basolateral transport of E-cadherin. Mol Biol Cell (2005) 2.74
The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans. J Immunol (2008) 2.71
The ins and outs of E-cadherin trafficking. Trends Cell Biol (2004) 2.70
Identification of putative noncoding RNAs among the RIKEN mouse full-length cDNA collection. Genome Res (2003) 2.63
Signal integration between IFNgamma and TLR signalling pathways in macrophages. Immunobiology (2006) 2.55
Apoptotic cell removal in development and tissue homeostasis. Trends Immunol (2006) 2.51
Transcript annotation in FANTOM3: mouse gene catalog based on physical cDNAs. PLoS Genet (2006) 2.48
Pivotal Advance: Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products. J Leukoc Biol (2010) 2.45
A role for the phagosome in cytokine secretion. Science (2005) 2.45
Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo. J Immunol (2008) 2.39
Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function. Hepatology (2011) 2.27
Development and evaluation of an automated annotation pipeline and cDNA annotation system. Genome Res (2003) 2.15
Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. J Leukoc Biol (2010) 2.07
Characterization of E-cadherin endocytosis in isolated MCF-7 and chinese hamster ovary cells: the initial fate of unbound E-cadherin. J Biol Chem (2003) 2.05
Systematic expression profiling of the mouse transcriptome using RIKEN cDNA microarrays. Genome Res (2003) 1.98
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science (2015) 1.91
Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model. J Bone Miner Res (2011) 1.76
Active Rab11 and functional recycling endosome are required for E-cadherin trafficking and lumen formation during epithelial morphogenesis. Am J Physiol Cell Physiol (2008) 1.76
IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1. J Exp Med (2013) 1.73
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages. Proc Natl Acad Sci U S A (2012) 1.72
Transcriptional network dynamics in macrophage activation. Genomics (2006) 1.72
A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis. Am J Pathol (2009) 1.70
The molecular basis for the lack of immunostimulatory activity of vertebrate DNA. J Immunol (2003) 1.67
EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin. J Cell Sci (2007) 1.64
Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter. Dev Biol (2007) 1.61
The mouse secretome: functional classification of the proteins secreted into the extracellular environment. Genome Res (2003) 1.61
The FANTOM web resource: from mammalian transcriptional landscape to its dynamic regulation. Genome Biol (2009) 1.60
Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice. J Leukoc Biol (2007) 1.57
Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal-/- mice. Am J Pathol (2006) 1.57
The trans-Golgi network golgin, GCC185, is required for endosome-to-Golgi transport and maintenance of Golgi structure. Traffic (2007) 1.54
Receptor function, dominant negative activity and phenotype correlations for MC1R variant alleles. Hum Mol Genet (2007) 1.52
LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression. FASEB J (2006) 1.51
Genetic control of the innate immune response. BMC Immunol (2003) 1.50
Mice and men: their promoter properties. PLoS Genet (2006) 1.50
GRIP domain-mediated targeting of two new coiled-coil proteins, GCC88 and GCC185, to subcompartments of the trans-Golgi network. J Biol Chem (2002) 1.48
Protein kinase C regulates endocytosis and recycling of E-cadherin. Am J Physiol Cell Physiol (2002) 1.44
Regulation of endocytosis, nuclear translocation, and signaling of fibroblast growth factor receptor 1 by E-cadherin. Mol Biol Cell (2004) 1.43
Renal structural and functional repair in a mouse model of reversal of ureteral obstruction. J Am Soc Nephrol (2005) 1.40
Nuclear translocation of cell-surface receptors: lessons from fibroblast growth factor. Traffic (2005) 1.39
Gpnmb is induced in macrophages by IFN-gamma and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses. J Immunol (2007) 1.37
Colony-stimulating factor-1 promotes kidney growth and repair via alteration of macrophage responses. Am J Pathol (2011) 1.37
Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. Immunology (2007) 1.35
Cytokine release from innate immune cells: association with diverse membrane trafficking pathways. Blood (2011) 1.34
G-protein-coupled receptor expression, function, and signaling in macrophages. J Leukoc Biol (2007) 1.33
Analysis of cultured human melanocytes based on polymorphisms within the SLC45A2/MATP, SLC24A5/NCKX5, and OCA2/P loci. J Invest Dermatol (2008) 1.33
Domains of the TGN: coats, tethers and G proteins. Traffic (2004) 1.32
FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions. Genome Biol (2009) 1.32
Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations. Immunobiology (2010) 1.32
Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFalpha. J Cell Biol (2007) 1.32
Systematic characterization of the zinc-finger-containing proteins in the mouse transcriptome. Genome Res (2003) 1.31
The colony-stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion. J Immunol (2005) 1.31
The mononuclear phagocyte system of the pig as a model for understanding human innate immunity and disease. J Leukoc Biol (2011) 1.30
Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk. Hum Mol Genet (2005) 1.30
Generation of diversity in the innate immune system: macrophage heterogeneity arises from gene-autonomous transcriptional probability of individual inducible genes. J Immunol (2002) 1.28
Cytokine secretion via cholesterol-rich lipid raft-associated SNAREs at the phagocytic cup. J Biol Chem (2006) 1.27
A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo. Proc Natl Acad Sci U S A (2008) 1.24
Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages. J Immunol (2002) 1.23
Osteal macrophages: a new twist on coupling during bone dynamics. Bone (2008) 1.23
Pig bone marrow-derived macrophages resemble human macrophages in their response to bacterial lipopolysaccharide. J Immunol (2012) 1.23
The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion. Curr Biol (2003) 1.22
CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway. J Immunol (2006) 1.21
N4WBP5A (Ndfip2), a Nedd4-interacting protein, localizes to multivesicular bodies and the Golgi, and has a potential role in protein trafficking. J Cell Sci (2004) 1.20
Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Proc Natl Acad Sci U S A (2007) 1.20
Inhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella. EMBO J (2010) 1.19
E-cadherin transport from the trans-Golgi network in tubulovesicular carriers is selectively regulated by golgin-97. Traffic (2005) 1.19
A gene expression atlas of the domestic pig. BMC Biol (2012) 1.18
Inflammation suppressor genes: please switch out all the lights. J Leukoc Biol (2005) 1.17
Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. Blood (2009) 1.16
Structural and functional annotation of the porcine immunome. BMC Genomics (2013) 1.16
Probing the S100 protein family through genomic and functional analysis. Genomics (2004) 1.15
Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis. Cancer Res (2007) 1.15
Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression. Arterioscler Thromb Vasc Biol (2006) 1.14
CSF-1 as a regulator of macrophage activation and immune responses. Arch Immunol Ther Exp (Warsz) (2003) 1.14