Published in Neural Plast on February 14, 2016
Glial Cells and Synaptic Plasticity. Neural Plast (2016) 0.75
Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron (1996) 7.20
Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression. Nature (2005) 7.19
Structure of a glutamate transporter homologue from Pyrococcus horikoshii. Nature (2004) 6.02
Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. Nature (2007) 4.14
An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature (1995) 4.14
Primary structure and functional characterization of a high-affinity glutamate transporter. Nature (1992) 3.69
Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors. Pharmacol Ther (2003) 3.36
Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J Neurosci (1994) 3.34
Cloning and expression of a rat brain L-glutamate transporter. Nature (1992) 3.14
Transport mechanism of a bacterial homologue of glutamate transporters. Nature (2009) 3.12
Glutamate transporters: confining runaway excitation by shaping synaptic transmission. Nat Rev Neurosci (2007) 2.92
Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance. Proc Natl Acad Sci U S A (1997) 2.86
Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain. Proc Natl Acad Sci U S A (1992) 2.59
Mortality in Parkinson's disease and its association with dementia and depression. Acta Neurol Scand (2004) 2.47
Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors. Biochem J (2001) 2.17
Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists. J Neurosci (1988) 2.14
Mechanism of ceftriaxone induction of excitatory amino acid transporter-2 expression and glutamate uptake in primary human astrocytes. J Biol Chem (2008) 2.08
Brain glutamate transporter proteins form homomultimers. J Biol Chem (1996) 2.01
Crystal structure of an asymmetric trimer of a bacterial glutamate transporter homolog. Nat Struct Mol Biol (2012) 1.77
Surface diffusion of astrocytic glutamate transporters shapes synaptic transmission. Nat Neurosci (2015) 1.74
Excitotoxicity: bridge to various triggers in neurodegenerative disorders. Eur J Pharmacol (2012) 1.70
A neuronal glutamate transporter contributes to neurotransmitter GABA synthesis and epilepsy. J Neurosci (2002) 1.69
Structural features of the glutamate transporter family. Microbiol Mol Biol Rev (1999) 1.60
Neuronal transporters regulate glutamate clearance, NMDA receptor activation, and synaptic plasticity in the hippocampus. J Neurosci (2009) 1.54
Regulation of the glial Na+-dependent glutamate transporters by cyclic AMP analogs and neurons. Mol Pharmacol (1998) 1.49
Mechanisms of glutamate transport. Physiol Rev (2013) 1.24
Cellular and subcellular mRNA localization of glutamate transporter isoforms GLT1a and GLT1b in rat brain by in situ hybridization. J Comp Neurol (2005) 1.22
The density of EAAC1 (EAAT3) glutamate transporters expressed by neurons in the mammalian CNS. J Neurosci (2012) 1.15
N-acetylcysteine prevents loss of dopaminergic neurons in the EAAC1-/- mouse. Ann Neurol (2010) 1.14
Translational control of glial glutamate transporter EAAT2 expression. J Biol Chem (2006) 1.14
Coupled ion binding and structural transitions along the transport cycle of glutamate transporters. Elife (2014) 1.12
Inhibition of microRNA-181 reduces forebrain ischemia-induced neuronal loss. J Cereb Blood Flow Metab (2013) 1.11
Shaping the synaptic signal: molecular mobility inside and outside the cleft. Trends Neurosci (2011) 1.09
Glutamatergic mechanisms in the dyskinesias induced by pharmacological dopamine replacement and deep brain stimulation for the treatment of Parkinson's disease. Prog Neurobiol (2011) 1.09
Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection. J Clin Invest (2014) 1.06
Aging: an important factor for the pathogenesis of neurodegenerative diseases. Mech Ageing Dev (2008) 1.06
Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease. Exp Neurol (2009) 1.04
Cortical regulation of striatal medium spiny neuron dendritic remodeling in parkinsonism: modulation of glutamate release reverses dopamine depletion-induced dendritic spine loss. Cereb Cortex (2010) 0.99
Nuclear factor erythroid 2-related factor 2 facilitates neuronal glutathione synthesis by upregulating neuronal excitatory amino acid transporter 3 expression. J Neurosci (2011) 0.95
l-dopa-induced reversal in striatal glutamate following partial depletion of nigrostriatal dopamine with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neuroscience (2005) 0.94
Downregulation of glial glutamate transporters after dopamine denervation in the striatum of 6-hydroxydopamine-lesioned rats. J Comp Neurol (2008) 0.94
Glutamate transport and metabolism in dopaminergic neurons of substantia nigra: implications for the pathogenesis of Parkinson's disease. J Neurol (2000) 0.93
Conditional deletion of the glutamate transporter GLT-1 reveals that astrocytic GLT-1 protects against fatal epilepsy while neuronal GLT-1 contributes significantly to glutamate uptake into synaptosomes. J Neurosci (2015) 0.93
Glutamate transporters EAAT4 and EAAT5 are expressed in vestibular hair cells and calyx endings. PLoS One (2012) 0.92
Update on the neurobiology of schizophrenia: a role for extracellular microdomains. Minerva Psichiatr (2012) 0.91
Role of glutamate in neurodegeneration of dopamine neurons in several animal models of parkinsonism. Amino Acids (1998) 0.91
Time-dependent changes in GLT-1 functioning in striatum of hemi-Parkinson rats. Neurochem Int (2010) 0.91
Kainate, N-methylaspartate and other excitatory amino acids increase calcium influx into rat brain cortex cells in vitro. Neurosci Lett (1983) 0.90
KATP channel openers facilitate glutamate uptake by GluTs in rat primary cultured astrocytes. Neuropsychopharmacology (2007) 0.90
Preferential vulnerability of mesencephalic dopamine neurons to glutamate transporter dysfunction. J Neurochem (2007) 0.90
Transient striatal GLT-1 blockade increases EAAC1 expression, glutamate reuptake, and decreases tyrosine hydroxylase phosphorylation at ser(19). Exp Neurol (2012) 0.89
Astroglial glutamate transporter deficiency increases synaptic excitability and leads to pathological repetitive behaviors in mice. Neuropsychopharmacology (2015) 0.89
Astroglial plasticity and glutamate function in a chronic mouse model of Parkinson's disease. Exp Neurol (2004) 0.89
Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction. Eur J Neurosci (2007) 0.88
Antiparkinsonian and antidyskinetic activity of drugs targeting central glutamatergic mechanisms. J Neurol (2000) 0.87
Inflammatory response in Parkinson's disease (Review). Mol Med Rep (2014) 0.87
Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP. Learn Mem (2012) 0.86
Neuropsychiatric symptoms in Parkinson's disease with mild cognitive impairment and dementia. Parkinsons Dis (2012) 0.86
Role of Astrocytes in Delayed Neuronal Death: GLT-1 and its Novel Regulation by MicroRNAs. Adv Neurobiol (2014) 0.86
A further update on the role of excitotoxicity in the pathogenesis of Parkinson's disease. J Neural Transm (Vienna) (2014) 0.84
Ceftriaxone ameliorates motor deficits and protects dopaminergic neurons in 6-hydroxydopamine-lesioned rats. ACS Chem Neurosci (2011) 0.83
Rhythmic oscillations of the microRNA miR-96-5p play a neuroprotective role by indirectly regulating glutathione levels. Nat Commun (2014) 0.83
Enhancement of glutamate uptake in 1-methyl-4-phenylpyridinium-treated astrocytes by trichostatin A. Neuroreport (2008) 0.83
Time-Dependent Compensatory Responses to Chronic Neuroinflammation in Hippocampus and Brainstem: The Potential Role of Glutamate Neurotransmission. J Alzheimers Dis Parkinsonism (2013) 0.82
Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment. Neurochem Res (2012) 0.81
Disruption of Eaat2b, a glutamate transporter, results in abnormal motor behaviors in developing zebrafish. Dev Biol (2011) 0.81
Progressive Parkinsonism by acute dysfunction of excitatory amino acid transporters in the rat substantia nigra. Neurobiol Dis (2014) 0.81
Risk of Parkinson's disease following anxiety disorders: a nationwide population-based cohort study. Eur J Neurol (2015) 0.81
Ceftriaxone increases glutamate uptake and reduces striatal tyrosine hydroxylase loss in 6-OHDA Parkinson's model. Mol Neurobiol (2013) 0.80
Effects of ceftriaxone on the behavioral and neuronal changes in an MPTP-induced Parkinson's disease rat model. Behav Brain Res (2014) 0.80
Effect of glutamate and antagonists of N-methyl-D-aspartate receptors on experimental parkinsonian syndrome in rats. Bull Exp Biol Med (2000) 0.80
Targeting glutamatergic synapses in Parkinson's disease. Curr Opin Pharmacol (2014) 0.80
Enhanced glutamate, IP3 and cAMP activity in the cerebral cortex of unilateral 6-hydroxydopamine induced Parkinson's rats: effect of 5-HT, GABA and bone marrow cell supplementation. J Biomed Sci (2011) 0.79
Glutamate-based depression GBD. Med Hypotheses (2012) 0.79
The effects of the β-lactam antibiotic, ceftriaxone, on forepaw stepping and L-DOPA-induced dyskinesia in a rodent model of Parkinson's disease. Psychopharmacology (Berl) (2014) 0.79
Glutamate and NMDA receptors activation leads to cerebellar dysfunction and impaired motor coordination in unilateral 6-hydroxydopamine lesioned Parkinson's rat: functional recovery with bone marrow cells, serotonin and GABA. Mol Cell Biochem (2011) 0.79
Glutamatergic pathways as a target for the treatment of dyskinesias in Parkinson's disease. Biochem Soc Trans (2014) 0.79
Decreased platelet glutamate uptake and genetic risk factors in patients with Parkinson's disease. Neurol Sci (2001) 0.79
Effect of Rivastigmine on Behavioral and Psychiatric Symptoms of Parkinson's Disease Dementia. J Mov Disord (2015) 0.78
Ceftriaxone Protects Astrocytes from MPP(+) via Suppression of NF-κB/JNK/c-Jun Signaling. Mol Neurobiol (2014) 0.78
Ceftriaxone prevents and reverses behavioral and neuronal deficits in an MPTP-induced animal model of Parkinson's disease dementia. Neuropharmacology (2014) 0.77
Alpha-synuclein modulates NR2B-containing NMDA receptors and decreases their levels after rotenone exposure. Neurochem Int (2015) 0.77
Exercise-Mediated Increase in Nigral Tyrosine Hydroxylase Is Accompanied by Increased Nigral GFR-α1 and EAAC1 Expression in Aging Rats. ACS Chem Neurosci (2015) 0.76
Dopamine denervation of the prefrontal cortex increases expression of the astrocytic glutamate transporter GLT-1. J Neurochem (2014) 0.76
Alterations in the motor cortical and striatal glutamatergic system and D-serine levels in the bilateral 6-hydroxydopamine rat model for Parkinson's disease. Neurochem Int (2015) 0.76