Published in PLoS One on March 24, 2016
The enigmatic PE/PPE Multi-gene Family of Mycobacteria and TB Vaccination. Infect Immun (2017) 0.76
Immunological consequences of strain variation within the Mycobacterium tuberculosis complex. Eur J Immunol (2017) 0.75
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature (1998) 60.62
Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology. J Clin Microbiol (1993) 45.22
Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination. Proc Natl Acad Sci U S A (1997) 15.25
The competitive cost of antibiotic resistance in Mycobacterium tuberculosis. Science (2006) 5.41
High functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demography. PLoS Biol (2008) 4.74
Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans. Nat Genet (2013) 3.89
Progression to active tuberculosis, but not transmission, varies by Mycobacterium tuberculosis lineage in The Gambia. J Infect Dis (2008) 3.15
Origin, spread and demography of the Mycobacterium tuberculosis complex. PLoS Pathog (2008) 3.10
MIRU-VNTRplus: a web tool for polyphasic genotyping of Mycobacterium tuberculosis complex bacteria. Nucleic Acids Res (2010) 3.02
Vaccines against tuberculosis: where are we and where do we need to go? PLoS Pathog (2012) 2.87
The protective effect of the Mycobacterium bovis BCG vaccine is increased by coadministration with the Mycobacterium tuberculosis 72-kilodalton fusion polyprotein Mtb72F in M. tuberculosis-infected guinea pigs. Infect Immun (2004) 1.90
Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys. Proc Natl Acad Sci U S A (2009) 1.86
Scale-up of services and research priorities for diagnosis, management, and control of tuberculosis: a call to action. Lancet (2010) 1.69
Mycobacterial PE/PPE proteins at the host-pathogen interface. Clin Dev Immunol (2011) 1.62
Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage. Nat Genet (2015) 1.57
The candidate tuberculosis vaccine Mtb72F/AS02A: Tolerability and immunogenicity in humans. Hum Vaccin (2009) 1.37
The PPE18 of Mycobacterium tuberculosis interacts with TLR2 and activates IL-10 induction in macrophage. J Immunol (2009) 1.32
Consequences of genomic diversity in Mycobacterium tuberculosis. Semin Immunol (2014) 1.30
Clade-specific virulence patterns of Mycobacterium tuberculosis complex strains in human primary macrophages and aerogenically infected mice. MBio (2013) 1.22
Mycobacterium tuberculosis strains of the modern sublineage of the Beijing family are more likely to display increased virulence than strains of the ancient sublineage. J Clin Microbiol (2014) 1.18
Frequent homologous recombination events in Mycobacterium tuberculosis PE/PPE multigene families: potential role in antigenic variability. J Bacteriol (2008) 1.10
Immunogenicity of Mycobacterium tuberculosis antigens in Mycobacterium bovis BCG-vaccinated and M. bovis-infected cattle. Infect Immun (2006) 1.07
DNA polymorphisms in the pepA and PPE18 genes among clinical strains of Mycobacterium tuberculosis: implications for vaccine efficacy. Infect Immun (2007) 1.05
Modeling the effects of strain diversity and mechanisms of strain competition on the potential performance of new tuberculosis vaccines. Proc Natl Acad Sci U S A (2008) 1.00
Using epitope predictions to evaluate efficacy and population coverage of the Mtb72f vaccine for tuberculosis. BMC Immunol (2010) 0.96
Diversity and disease pathogenesis in Mycobacterium tuberculosis. Trends Microbiol (2014) 0.92
Vaccine against tuberculosis: what's new? BMC Infect Dis (2014) 0.88
Immunogenic Mycobacterium africanum strains associated with ongoing transmission in The Gambia. Emerg Infect Dis (2013) 0.88
Estimating the mutation rate of Mycobacterium tuberculosis during infection. Nat Genet (2011) 0.87
The PPE18 protein of Mycobacterium tuberculosis inhibits NF-κB/rel-mediated proinflammatory cytokine production by upregulating and phosphorylating suppressor of cytokine signaling 3 protein. J Immunol (2011) 0.86
Immunoregulatory functions and expression patterns of PE/PPE family members: Roles in pathogenicity and impact on anti-tuberculosis vaccine and drug design. IUBMB Life (2015) 0.85
Pathogen evolution and the immunological niche. Ann N Y Acad Sci (2014) 0.85
Role of PPE18 protein in intracellular survival and pathogenicity of Mycobacterium tuberculosis in mice. PLoS One (2012) 0.85
Assessment of the genetic diversity of Mycobacterium tuberculosis esxA, esxH, and fbpB genes among clinical isolates and its implication for the future immunization by new tuberculosis subunit vaccines Ag85B-ESAT-6 and Ag85B-TB10.4. J Biomed Biotechnol (2010) 0.84
Increased level of acute phase reactants in patients infected with modern Mycobacterium tuberculosis genotypes in Mwanza, Tanzania. BMC Infect Dis (2014) 0.79
Sequence conservation analysis and in silico human leukocyte antigen-peptide binding predictions for the Mtb72F and M72 tuberculosis candidate vaccine antigens. BMC Immunol (2015) 0.76