Published in J Immunol on October 30, 2009
Mycobacterial PE/PPE proteins at the host-pathogen interface. Clin Dev Immunol (2011) 1.62
Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway. J Biol Chem (2011) 1.27
Comparative analysis of Mycobacterium tuberculosis pe and ppe genes reveals high sequence variation and an apparent absence of selective constraints. PLoS One (2012) 1.23
Src homology 3-interacting domain of Rv1917c of Mycobacterium tuberculosis induces selective maturation of human dendritic cells by regulating PI3K-MAPK-NF-kappaB signaling and drives Th2 immune responses. J Biol Chem (2010) 1.20
Interleukin-10 and immunity against prokaryotic and eukaryotic intracellular pathogens. Infect Immun (2011) 1.16
Comparative genomic and proteomic analyses of PE/PPE multigene family of Mycobacterium tuberculosis H₃₇Rv and H₃₇Ra reveal novel and interesting differences with implications in virulence. Nucleic Acids Res (2012) 0.99
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Pulmonary mycobacterial granuloma increased IL-10 production contributes to establishing a symbiotic host-microbe microenvironment. Am J Pathol (2011) 0.93
The Mycobacterium tuberculosis PE proteins Rv0285 and Rv1386 modulate innate immunity and mediate bacillary survival in macrophages. PLoS One (2012) 0.93
PE11 (Rv1169c) selectively alters fatty acid components of Mycobacterium smegmatis and host cell interleukin-6 level accompanied with cell death. Front Microbiol (2015) 0.92
Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity-mediated antimicrobial responses with caseation during mycobacterium tuberculosis infection. J Immunol (2014) 0.91
Understanding delayed T-cell priming, lung recruitment, and airway luminal T-cell responses in host defense against pulmonary tuberculosis. Clin Dev Immunol (2012) 0.91
Chitin particles induce size-dependent but carbohydrate-independent innate eosinophilia. J Leukoc Biol (2011) 0.89
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Sensing of Mycobacterium tuberculosis and consequences to both host and bacillus. Immunol Rev (2015) 0.86
Endocytosis of Mycobacterium tuberculosis heat shock protein 60 is required to induce interleukin-10 production in macrophages. J Biol Chem (2013) 0.86
Role of PPE18 protein in intracellular survival and pathogenicity of Mycobacterium tuberculosis in mice. PLoS One (2012) 0.85
PPE38 of Mycobacterium marinum triggers the cross-talk of multiple pathways involved in the host response, as revealed by subcellular quantitative proteomics. J Proteome Res (2013) 0.85
Lipoglycans contribute to innate immune detection of mycobacteria. PLoS One (2011) 0.85
HIV-1 infection of macrophages dysregulates innate immune responses to Mycobacterium tuberculosis by inhibition of interleukin-10. J Infect Dis (2013) 0.84
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Mycobacterium tuberculosis Rv0652 stimulates production of tumour necrosis factor and monocytes chemoattractant protein-1 in macrophages through the Toll-like receptor 4 pathway. Immunology (2012) 0.83
Proline-proline-glutamic acid (PPE) protein Rv1168c of Mycobacterium tuberculosis augments transcription from HIV-1 long terminal repeat promoter. J Biol Chem (2012) 0.83
Structure and dynamic behavior of Toll-like receptor 2 subfamily triggered by malarial glycosylphosphatidylinositols of Plasmodium falciparum. FEBS J (2013) 0.82
Mycobacterium tuberculosis Rv3402c enhances mycobacterial survival within macrophages and modulates the host pro-inflammatory cytokines production via NF-kappa B/ERK/p38 signaling. PLoS One (2014) 0.82
Expression of a Gene Encoding 34.9 kDa PPE Antigen of Mycobacterium avium subsp. paratuberculosis in E. coli. Mol Biol Int (2010) 0.82
Phosphorylation of mitogen-activated protein kinases contributes to interferon γ production in response to Mycobacterium tuberculosis. J Infect Dis (2012) 0.81
Extracellular mycobacterial DnaK polarizes macrophages to the M2-like phenotype. PLoS One (2014) 0.81
PPE26 induces TLR2-dependent activation of macrophages and drives Th1-type T-cell immunity by triggering the cross-talk of multiple pathways involved in the host response. Oncotarget (2015) 0.80
Exogenous control of the expression of Group I CD1 molecules competent for presentation of microbial nonpeptide antigens to human T lymphocytes. Clin Dev Immunol (2011) 0.78
Identification of a unique TLR2-interacting peptide motif in a microbial leucine-rich repeat protein. Biochem Biophys Res Commun (2012) 0.78
A putative nitroreductase from the DosR regulon of Mycobacterium tuberculosis induces pro-inflammatory cytokine expression via TLR2 signaling pathway. Sci Rep (2016) 0.77
Mycobacterium tuberculosis Rv2882c Protein Induces Activation of Macrophages through TLR4 and Exhibits Vaccine Potential. PLoS One (2016) 0.77
IL-27 Suppresses Antimicrobial Activity in Human Leprosy. J Invest Dermatol (2015) 0.77
Gene expression profile and immunological evaluation of unique hypothetical unknown proteins of Mycobacterium leprae by using quantitative real-time PCR. Clin Vaccine Immunol (2012) 0.77
Mycobacterium tuberculosis Rv3628 drives Th1-type T cell immunity via TLR2-mediated activation of dendritic cells and displays vaccine potential against the hyper-virulent Beijing K strain. Oncotarget (2016) 0.77
Mycobacterium tuberculosis PE25/PPE41 protein complex induces activation and maturation of dendritic cells and drives Th2-biased immune responses. Med Microbiol Immunol (2015) 0.76
Mycobacterium tuberculosis Peptidyl-Prolyl Isomerases Are Immunogenic, Alter Cytokine Profile and Aid in Intracellular Survival. Front Cell Infect Microbiol (2017) 0.76
Mycobacterium tuberculosis PPE32 promotes cytokines production and host cell apoptosis through caspase cascade accompanying with enhanced ER stress response. Oncotarget (2016) 0.75
Leptospira surface adhesin (Lsa21) induces Toll like receptor 2 and 4 mediated inflammatory responses in macrophages. Sci Rep (2016) 0.75
High Sequence Variability of the ppE18 Gene of Clinical Mycobacterium tuberculosis Complex Strains Potentially Impacts Effectivity of Vaccine Candidate M72/AS01E. PLoS One (2016) 0.75
Phosphate responsive regulation provides insights for ESX-5 function in Mycobacterium tuberculosis. Curr Genet (2016) 0.75
NMAAP1 Expressed in BCG-Activated Macrophage Promotes M1 Macrophage Polarization. Mol Cells (2015) 0.75
Modulation of Trehalose Dimycolate and Immune System by Rv0774c Protein Enhanced the Intracellular Survival of Mycobacterium smegmatis in Human Macrophages Cell Line. Front Cell Infect Microbiol (2017) 0.75
Mycobacterium tuberculosis DosR Regulon Gene Rv2004c Encodes a Novel Antigen with Pro-inflammatory Functions and Potential Diagnostic Application for Detection of Latent Tuberculosis. Front Immunol (2017) 0.75
T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity. Circulation (2007) 6.23
Molecular characterization of multidrug-resistant isolates of Mycobacterium tuberculosis from patients in North India. Antimicrob Agents Chemother (2002) 2.59
Human resistin stimulates the pro-inflammatory cytokines TNF-alpha and IL-12 in macrophages by NF-kappaB-dependent pathway. Biochem Biophys Res Commun (2005) 2.20
Pneumonectomy for stage I (T1N0 and T2N0) nonsmall cell lung cancer has potent, adverse impact on survival. Ann Thorac Surg (2003) 2.15
Genomic fluidity and pathogenic bacteria: applications in diagnostics, epidemiology and intervention. Nat Rev Microbiol (2008) 1.96
Predominance of ancestral lineages of Mycobacterium tuberculosis in India. Emerg Infect Dis (2006) 1.75
PPE antigen Rv2430c of Mycobacterium tuberculosis induces a strong B-cell response. Infect Immun (2003) 1.72
Genetic analysis of traditional and evolved Basmati and non-Basmati rice varieties by using fluorescence-based ISSR-PCR and SSR markers. Proc Natl Acad Sci U S A (2002) 1.61
Early secreted antigen ESAT-6 of Mycobacterium tuberculosis promotes protective T helper 17 cell responses in a toll-like receptor-2-dependent manner. PLoS Pathog (2011) 1.46
Early, structured disease modifying anti-rheumatic drug (DMARD) therapy reduces cardiovascular risk in rheumatoid arthritis--a single centre study using non-biologic drugs. J Assoc Physicians India (2013) 1.42
Polyphasic taxonomic analysis establishes Mycobacterium indicus pranii as a distinct species. PLoS One (2009) 1.36
The TB structural genomics consortium: providing a structural foundation for drug discovery. Curr Drug Targets Infect Disord (2002) 1.28
The extracytoplasmic function sigma factors: role in bacterial pathogenesis. Infect Genet Evol (2004) 1.24
Pathogen-specific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12. Immunity (2013) 1.24
Inferring genome-wide functional linkages in E. coli by combining improved genome context methods: comparison with high-throughput experimental data. Genome Res (2007) 1.23
Comparative proteomic analysis of sequential isolates of Mycobacterium tuberculosis from a patient with pulmonary tuberculosis turning from drug sensitive to multidrug resistant. Indian J Med Res (2015) 1.22
Use of fluorescent amplified fragment length polymorphism for molecular epidemiology of leptospirosis in India. J Clin Microbiol (2004) 1.22
Mycobacterium tuberculosis secretory proteins CFP-10, ESAT-6 and the CFP10:ESAT6 complex inhibit lipopolysaccharide-induced NF-kappaB transactivation by downregulation of reactive oxidative species (ROS) production. Immunol Cell Biol (2007) 1.21
Clusters of PE and PPE genes of Mycobacterium tuberculosis are organized in operons: evidence that PE Rv2431c is co-transcribed with PPE Rv2430c and their gene products interact with each other. FEBS Lett (2006) 1.20
Cloning, expression, and purification of a novel recombinant antigen from Leishmania donovani. Protein Expr Purif (2005) 1.19
Iron-dependent RNA-binding activity of Mycobacterium tuberculosis aconitase. J Bacteriol (2007) 1.19
Rapid identification of Mycobacterium tuberculosis Beijing genotypes on the basis of the mycobacterial interspersed repetitive unit locus 26 signature. J Clin Microbiol (2006) 1.19
Identification of novel mutations causing familial primary congenital glaucoma in Indian pedigrees. Invest Ophthalmol Vis Sci (2002) 1.18
The PE/PPE multigene family codes for virulence factors and is a possible source of mycobacterial antigenic variation: perhaps more? Biochimie (2011) 1.14
The unusual chaperonins of Mycobacterium tuberculosis. Tuberculosis (Edinb) (2005) 1.13
Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics. Microbiology (2005) 1.13
Functional studies of multiple thioredoxins from Mycobacterium tuberculosis. J Bacteriol (2008) 1.12
Mycobacterium tuberculosis (Mtb) isocitrate dehydrogenases show strong B cell response and distinguish vaccinated controls from TB patients. Proc Natl Acad Sci U S A (2004) 1.12
Mechanistic insights into a novel exporter-importer system of Mycobacterium tuberculosis unravel its role in trafficking of iron. PLoS One (2008) 1.12
Role of M. tuberculosis RD-1 region encoded secretory proteins in protective response and virulence. Tuberculosis (Edinb) (2008) 1.11
Vertical transmission of hepatitis B virus despite maternal lamivudine therapy. Lancet (2002) 1.11
Prevalence and significance of vitamin D deficiency and insufficiency among apparently healthy adults. Clin Biochem (2010) 1.10
Neurological complications of dengue fever: Experience from a tertiary center of north India. Ann Indian Acad Neurol (2011) 1.10
Correlations of genotype with phenotype in Indian patients with primary congenital glaucoma. Invest Ophthalmol Vis Sci (2004) 1.09
Molecular genotyping of a large, multicentric collection of tubercle bacilli indicates geographical partitioning of strain variation and has implications for global epidemiology of Mycobacterium tuberculosis. J Clin Microbiol (2004) 1.09
Conformational flexibility of Mycobacterium tuberculosis thioredoxin reductase: crystal structure and normal-mode analysis. Acta Crystallogr D Biol Crystallogr (2005) 1.09
Distinctiveness of Mycobacterium tuberculosis genotypes from human immunodeficiency virus type 1-seropositive and -seronegative patients in Lima, Peru. J Clin Microbiol (2003) 1.08
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Crystal structure of the 65-kilodalton heat shock protein, chaperonin 60.2, of Mycobacterium tuberculosis. J Bacteriol (2004) 1.07
Analysis of genomic downsizing on the basis of region-of-difference polymorphism profiling of Mycobacterium tuberculosis patient isolates reveals geographic partitioning. J Clin Microbiol (2005) 1.07
Expression and characterization of a recombinant kinesin antigen from an old Indian strain (DD8) of Leishmania donovani and comparing it with a commercially available antigen from a newly isolated (KE16) strain of L. donovani. Infect Genet Evol (2008) 1.07
Mycobacterium tuberculosis GroEL homologues unusually exist as lower oligomers and retain the ability to suppress aggregation of substrate proteins. J Mol Biol (2004) 1.06
Gln48His is the prevalent myocilin mutation in primary open angle and primary congenital glaucoma phenotypes in India. Mol Vis (2005) 1.06
Specific immunoassays confirm association of Mycobacterium avium Subsp. paratuberculosis with type-1 but not type-2 diabetes mellitus. PLoS One (2009) 1.06
PAR-3D: a server to predict protein active site residues. Nucleic Acids Res (2007) 1.05
Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53. PLoS One (2011) 1.05
Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c. Biochim Biophys Acta (2010) 1.04
Genome sequence based, comparative analysis of the fluorescent amplified fragment length polymorphisms (FAFLP) of tubercle bacilli from seals provides molecular evidence for a new species within the Mycobacterium tuberculosis complex. Infect Genet Evol (2003) 1.03
The genomic organization of mouse resistin reveals major differences from the human resistin: functional implications. Gene (2003) 1.03
Nontuberculous mycobacterial infections in Indian AIDS patients detected by a novel set of ESAT-6 polymerase chain reaction primers. Jpn J Infect Dis (2007) 1.03
Molecular analysis of a leprosy immunotherapeutic bacillus provides insights into Mycobacterium evolution. PLoS One (2007) 1.03
Mycobacterium tuberculosis evades host immunity by recruiting mesenchymal stem cells. Proc Natl Acad Sci U S A (2010) 1.02
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. Antimicrob Agents Chemother (2010) 1.02
Chimeric Vitreoscilla hemoglobin (VHb) carrying a flavoreductase domain relieves nitrosative stress in Escherichia coli: new insight into the functional role of VHb. Appl Environ Microbiol (2002) 1.01
Facilitated oligomerization of mycobacterial GroEL: evidence for phosphorylation-mediated oligomerization. J Bacteriol (2009) 1.01
Multiple gene duplication and rapid evolution in the groEL gene: functional implications. J Mol Evol (2006) 1.00
A novel nucleoid-associated protein of Mycobacterium tuberculosis is a sequence homolog of GroEL. Nucleic Acids Res (2009) 0.99
Comparative genomic and proteomic analyses of PE/PPE multigene family of Mycobacterium tuberculosis H₃₇Rv and H₃₇Ra reveal novel and interesting differences with implications in virulence. Nucleic Acids Res (2012) 0.99
Identification of R368H as a predominant CYP1B1 allele causing primary congenital glaucoma in Indian patients. Invest Ophthalmol Vis Sci (2003) 0.98
AmpliBASE MT: a Mycobacterium tuberculosis diversity knowledgebase. Bioinformatics (2004) 0.98
T cells from Programmed Death-1 deficient mice respond poorly to Mycobacterium tuberculosis infection. PLoS One (2011) 0.97
Mycobacterium tuberculosis conserved hypothetical protein rRv2626c modulates macrophage effector functions. Immunology (2010) 0.97
Airway smooth muscle in asthma: phenotype plasticity and function. Pulm Pharmacol Ther (2008) 0.96
Crystal structure of Mycobacterium tuberculosis YefM antitoxin reveals that it is not an intrinsically unstructured protein. J Mol Biol (2008) 0.96
Genome scale portrait of cAMP-receptor protein (CRP) regulons in mycobacteria points to their role in pathogenesis. Gene (2007) 0.96
Hydrogen peroxide inhibits IL-12 p40 induction in macrophages by inhibiting c-rel translocation to the nucleus through activation of calmodulin protein. Blood (2005) 0.96
Identification of a novel role of ESAT-6-dependent miR-155 induction during infection of macrophages with Mycobacterium tuberculosis. Cell Microbiol (2012) 0.96
Involvement of a nine-residue loop of streptokinase in the generation of macromolecular substrate specificity by the activator complex through interaction with substrate kringle domains. J Biol Chem (2002) 0.96
Effect of Mycobacterium tuberculosis-specific 10-kilodalton antigen on macrophage release of tumor necrosis factor alpha and nitric oxide. Infect Immun (2002) 0.95
Genetic structure of Indian populations based on fifteen autosomal microsatellite loci. BMC Genet (2006) 0.95
Disease-causing mutations in proteins: structural analysis of the CYP1B1 mutations causing primary congenital glaucoma in humans. Biophys J (2006) 0.95
Solitary pulmonary nodules: pathological outcome of 150 consecutively resected lesions. Interact Cardiovasc Thorac Surg (2004) 0.95
The co-operonic PE25/PPE41 protein complex of Mycobacterium tuberculosis elicits increased humoral and cell mediated immune response. PLoS One (2008) 0.95
Concurrent proinflammatory and apoptotic activity of a Helicobacter pylori protein (HP986) points to its role in chronic persistence. PLoS One (2011) 0.95
Transmission of G145R mutant of HBV to an unrelated contact. J Med Virol (2005) 0.94
Computational prediction and experimental verification of novel IdeR binding sites in the upstream sequences of Mycobacterium tuberculosis open reading frames. Bioinformatics (2005) 0.94
A multivalent combination of experimental antituberculosis DNA vaccines based on Ag85B and regions of difference antigens. Microbes Infect (2006) 0.94
Insulin increases the expression of contractile phenotypic markers in airway smooth muscle. Am J Physiol Cell Physiol (2007) 0.94
Understanding gait control in post-stroke: implications for management. J Bodyw Mov Ther (2010) 0.94
In-vitro helix opening of M. tuberculosis oriC by DnaA occurs at precise location and is inhibited by IciA like protein. PLoS One (2009) 0.94
Baculovirus as mammalian cell expression vector for gene therapy: an emerging strategy. Mol Ther (2002) 0.94
Ancestral Mycobacterium tuberculosis genotypes in India: implications for TB control programmes. Infect Genet Evol (2008) 0.93
Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targets. FEMS Microbiol Rev (2011) 0.93
Novel biochemical properties of a CRP/FNR family transcription factor from Mycobacterium tuberculosis. Int J Med Microbiol (2007) 0.93