Published in Sci Rep on April 11, 2016
Structure of lipid bilayers. Biochim Biophys Acta (2000) 11.31
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature (2006) 9.36
Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. Neurobiol Aging (2004) 7.83
Metabonomics: a platform for studying drug toxicity and gene function. Nat Rev Drug Discov (2002) 5.96
White matter in learning, cognition and psychiatric disorders. Trends Neurosci (2008) 4.72
Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis. J Biol Chem (1991) 2.70
Polyunsaturated fatty acids, inflammation, and immunity. Lipids (2001) 2.08
Longitudinal MRI and cognitive change in healthy elderly. Neuropsychology (2007) 1.88
Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiol Genomics (2006) 1.88
Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats. J Neurosci (2007) 1.86
Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero. Proc Natl Acad Sci U S A (2003) 1.79
Omega-3 fatty acids and inflammatory processes. Nutrients (2010) 1.70
Working memory for visual objects: complementary roles of inferior temporal, medial temporal, and prefrontal cortex. Neuroscience (2005) 1.61
Functional MRI studies of associative encoding in normal aging, mild cognitive impairment, and Alzheimer's disease. Ann N Y Acad Sci (2007) 1.58
Exceptional evolutionary divergence of human muscle and brain metabolomes parallels human cognitive and physical uniqueness. PLoS Biol (2014) 1.56
New evidence for neurotransmitter influences on brain development. Trends Neurosci (1997) 1.53
Glycerophospholipids in brain: their metabolism, incorporation into membranes, functions, and involvement in neurological disorders. Chem Phys Lipids (2000) 1.51
Neuron to glia signaling triggers myelin membrane exocytosis from endosomal storage sites. J Cell Biol (2006) 1.49
Acylcarnitines: role in brain. Prog Lipid Res (2009) 1.39
Potential metabolite markers of schizophrenia. Mol Psychiatry (2011) 1.35
Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients. J Clin Endocrinol Metab (2002) 1.25
Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? J Biol Chem (2009) 1.23
The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain. Glia (2010) 1.12
Rapid metabolic evolution in human prefrontal cortex. Proc Natl Acad Sci U S A (2011) 1.09
Phospholipase A2 and its role in brain tissue. J Neurochem (1997) 1.06
OST alpha-OST beta: a key membrane transporter of bile acids and conjugated steroids. Front Biosci (Landmark Ed) (2009) 1.05
Brain aging: impaired coding of novel environmental cues. J Neurosci (1997) 1.03
Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease. Trends Mol Med (2008) 1.03
Removal of cholesterol from extrahepatic sources by oxidative mechanisms. Curr Opin Lipidol (1999) 1.01
Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption. FASEB J (2013) 1.00
Omega-6/omega-3 ratio and brain-related functions. World Rev Nutr Diet (2003) 0.98
Frontal and temporal functional connections of the living human brain. Eur J Neurosci (2007) 0.96
Metabonomic alterations in hippocampus, temporal and prefrontal cortex with age in rats. Neurochem Int (2009) 0.94
Presence of protein-bound unconjugated bile acids in the cytoplasmic fraction of rat brain. J Lipid Res (2003) 0.91
The length of hippocampal cholinergic fibers is reduced in the aging brain. Neurobiol Aging (2007) 0.91
Efflux of taurocholic acid across the blood-brain barrier: interaction with cyclic peptides. J Pharmacol Exp Ther (1998) 0.87
Impact of fatty acids on brain circulation, structure and function. Prostaglandins Leukot Essent Fatty Acids (2014) 0.86
Lipid membrane domains in the brain. Biochim Biophys Acta (2015) 0.86
Plasma metabolite profiles of Alzheimer's disease and mild cognitive impairment. J Proteome Res (2014) 0.86
The bile steroid chenodeoxycholate is a potent antagonist at NMDA and GABA(A) receptors. Neurosci Lett (2011) 0.84
Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms. Dig Liver Dis (2014) 0.84
Patterns of lipid changes in membranes of the aged brain. Gerontology (1987) 0.83
The ratio of phosphatidylcholines to lysophosphatidylcholines in plasma differentiates healthy controls from patients with Alzheimer's disease and mild cognitive impairment. Alzheimers Dement (Amst) (2015) 0.82
Pleiotropic functions of the organic solute transporter Ostα-Ostβ. Dig Dis (2011) 0.82
Metabonomic profiling of TASTPM transgenic Alzheimer's disease mouse model. J Proteome Res (2012) 0.82
Decreased plasma and cerebrospinal fluid content of neuroactive steroids in Parkinson's disease. Neurol Sci (2003) 0.81
Functional modulation of nuclear steroid receptors by tauroursodeoxycholic acid reduces amyloid beta-peptide-induced apoptosis. Mol Endocrinol (2006) 0.81
Age- and gender-related metabonomic alterations in striatum and cerebellar cortex in rats. Brain Res (2013) 0.79
NMR metabonomics of cerebrospinal fluid distinguishes between Parkinson's disease and controls. Neurosci Lett (2015) 0.79
Lipids in the nervous system: from biochemistry and molecular biology to patho-physiology. Biochim Biophys Acta (2014) 0.78
Transcriptomic insights into human brain evolution: acceleration, neutrality, heterochrony. Curr Opin Genet Dev (2014) 0.78
Plasticity of neuronal connections in developing brains of mammals. Neurosci Res (1992) 0.78
Longitudinal 1H MRS of rat forebrain from infancy to adulthood reveals adolescence as a distinctive phase of neurometabolite development. NMR Biomed (2013) 0.77
The mouse brain metabolome: region-specific signatures and response to excitotoxic neuronal injury. Am J Pathol (2015) 0.76
Circulating Unsaturated Fatty Acids Delineate the Metabolic Status of Obese Individuals. EBioMedicine (2015) 0.92
Transcriptomic and metabonomic profiling reveal synergistic effects of quercetin and resveratrol supplementation in high fat diet fed mice. J Proteome Res (2012) 0.86
Sex-dependent effects on gut microbiota regulate hepatic carcinogenic outcomes. Sci Rep (2017) 0.79
Branched-chain and aromatic amino acid profiles and diabetes risk in Chinese populations. Sci Rep (2016) 0.79
Serum lipid alterations identified in chronic hepatitis B, hepatitis B virus-associated cirrhosis and carcinoma patients. Sci Rep (2017) 0.75
A panel of free fatty acid ratios to predict the development of metabolic abnormalities in healthy obese individuals. Sci Rep (2016) 0.75