Published in Crit Care on April 19, 2016
Effects of Levosimendan on Diaphragm Function in Mechanically Ventilated Patients | NCT01721434
Novel insights in ICU-acquired respiratory muscle dysfunction: implications for clinical care. Crit Care (2017) 0.75
Critical illness-associated diaphragm weakness. Intensive Care Med (2017) 0.75
Pathogen recognition and innate immunity. Cell (2006) 44.14
A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med (2003) 16.11
The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev (2002) 16.10
Hydrocortisone therapy for patients with septic shock. N Engl J Med (2008) 15.85
Early versus late parenteral nutrition in critically ill adults. N Engl J Med (2011) 12.10
Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med (2010) 10.44
Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med (2006) 9.52
A randomized trial of glutamine and antioxidants in critically ill patients. N Engl J Med (2013) 8.94
Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans. N Engl J Med (2008) 8.88
Paresis acquired in the intensive care unit: a prospective multicenter study. JAMA (2002) 7.04
ATS/ERS Statement on respiratory muscle testing. Am J Respir Crit Care Med (2002) 5.24
Increased mortality associated with growth hormone treatment in critically ill adults. N Engl J Med (1999) 4.63
Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial. JAMA (2013) 3.78
Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial. Lancet (2002) 3.18
Mitochondria-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness. Crit Care Med (2011) 2.25
Neural control of mechanical ventilation in respiratory failure. Nat Med (1999) 2.21
Disorders of the respiratory muscles. Am J Respir Crit Care Med (2003) 2.19
Rapidly progressive diaphragmatic weakness and injury during mechanical ventilation in humans. Am J Respir Crit Care Med (2010) 2.17
The application of esophageal pressure measurement in patients with respiratory failure. Am J Respir Crit Care Med (2014) 2.16
Diaphragm dysfunction on admission to the intensive care unit. Prevalence, risk factors, and prognostic impact-a prospective study. Am J Respir Crit Care Med (2013) 2.10
Pathophysiologic basis of acute respiratory distress in patients who fail a trial of weaning from mechanical ventilation. Am J Respir Crit Care Med (1997) 2.05
Diaphragm dysfunction assessed by ultrasonography: influence on weaning from mechanical ventilation. Crit Care Med (2011) 2.03
Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg (2002) 1.92
Assist-control mechanical ventilation attenuates ventilator-induced diaphragmatic dysfunction. Am J Respir Crit Care Med (2004) 1.92
Efficacy of ventilator waveforms observation in detecting patient-ventilator asynchrony. Crit Care Med (2011) 1.89
Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial. Lancet Respir Med (2013) 1.89
Both high level pressure support ventilation and controlled mechanical ventilation induce diaphragm dysfunction and atrophy. Crit Care Med (2012) 1.87
Caspase and calpain activation both contribute to sepsis-induced diaphragmatic weakness. J Appl Physiol (1985) (2009) 1.86
Trolox attenuates mechanical ventilation-induced diaphragmatic dysfunction and proteolysis. Am J Respir Crit Care Med (2004) 1.85
Sonographic evaluation of the diaphragm in critically ill patients. Technique and clinical applications. Intensive Care Med (2013) 1.84
Mechanical ventilation-induced diaphragm disuse in humans triggers autophagy. Am J Respir Crit Care Med (2010) 1.80
Respiratory and limb muscle weakness induced by tumor necrosis factor-alpha: involvement of muscle myofilaments. Am J Respir Crit Care Med (2002) 1.72
The calcium sensitizer levosimendan improves human diaphragm function. Am J Respir Crit Care Med (2012) 1.68
Nuclear factor-κB signaling contributes to mechanical ventilation-induced diaphragm weakness*. Crit Care Med (2012) 1.64
NF-kappaB activation and inhibition: a review. Shock (2002) 1.55
Clinical review: ventilator-induced diaphragmatic dysfunction--human studies confirm animal model findings! Crit Care (2011) 1.55
N-Acetylcysteine protects the rat diaphragm from the decreased contractility associated with controlled mechanical ventilation. Crit Care Med (2011) 1.54
Mechanisms and use of calcium-sensitizing agents in the failing heart. Circulation (2006) 1.53
Oxidative stress is required for mechanical ventilation-induced protease activation in the diaphragm. J Appl Physiol (1985) (2010) 1.53
Diaphragm muscle fiber weakness and ubiquitin-proteasome activation in critically ill patients. Am J Respir Crit Care Med (2015) 1.52
Toll-like receptor 4 signaling in ventilator-induced diaphragm atrophy. Anesthesiology (2012) 1.51
Bortezomib partially protects the rat diaphragm from ventilator-induced diaphragm dysfunction. Crit Care Med (2012) 1.51
Mechanical ventilation depresses protein synthesis in the rat diaphragm. Am J Respir Crit Care Med (2004) 1.50
Measurement of respiratory muscle strength. Thorax (1995) 1.44
Inspiratory muscle strength training improves weaning outcome in failure to wean patients: a randomized trial. Crit Care (2011) 1.40
Free radical-induced contractile protein dysfunction in endotoxin-induced sepsis. Am J Respir Cell Mol Biol (2001) 1.31
Diaphragm weakness in mechanically ventilated critically ill patients. Crit Care (2013) 1.30
Physiologic effects of nutritional support and anabolic steroids in patients with chronic obstructive pulmonary disease. A placebo-controlled randomized trial. Am J Respir Crit Care Med (1995) 1.25
The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill. Physiol Rev (2015) 1.20
Proteasome inhibition improves diaphragm function in congestive heart failure rats. Am J Physiol Lung Cell Mol Physiol (2008) 1.19
Diaphragm muscle thinning in patients who are mechanically ventilated. Chest (2012) 1.16
Effect of proteasome inhibitors on endotoxin-induced diaphragm dysfunction. Am J Physiol Lung Cell Mol Physiol (2009) 1.15
Clinical review: the ABC of weaning failure--a structured approach. Crit Care (2010) 1.15
Effect of respiratory muscle training on exercise performance in healthy individuals: a systematic review and meta-analysis. Sports Med (2012) 1.15
Ventilator-induced diaphragmatic dysfunction. Curr Opin Crit Care (2010) 1.14
Validation of a technique to assess maximal inspiratory pressure in poorly cooperative patients. Chest (1992) 1.11
Effects of acute administration of corticosteroids during mechanical ventilation on rat diaphragm. Am J Respir Crit Care Med (2008) 1.09
The unidirectional valve is the best method to determine maximal inspiratory pressure during weaning. Chest (1999) 1.07
Levosimendan enhances force generation of diaphragm muscle from patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2008) 1.03
A role for anabolic steroids in the rehabilitation of patients with COPD? A double-blind, placebo-controlled, randomized trial. Chest (2003) 1.03
Steroid-induced myopathy and its significance to respiratory disease: a known disease rediscovered. Eur Respir J (1992) 0.99
High-intensity inspiratory muscle training in COPD. Eur Respir J (2006) 0.98
Molecular mechanisms of intensive care unit-acquired weakness. Eur Respir J (2011) 0.97
Changes in the perception of inspiratory resistive loads during partial curarization. J Physiol (1980) 0.97
Plasma from septic shock patients induces loss of muscle protein. Crit Care (2011) 0.96
Measuring diaphragm thickness with ultrasound in mechanically ventilated patients: feasibility, reproducibility and validity. Intensive Care Med (2015) 0.95
Eicosapentaenoic acid preserves diaphragm force generation following endotoxin administration. Crit Care (2010) 0.95
Effect of N-acetylcysteine on human diaphragm strength and fatigability. Am J Respir Crit Care Med (1997) 0.94
An automated and standardized neural index to quantify patient-ventilator interaction. Crit Care (2013) 0.93
Hypercapnia attenuates ventilator-induced diaphragm atrophy and modulates dysfunction. Crit Care (2014) 0.92
Hemin prevents cardiac and diaphragm mitochondrial dysfunction in sepsis. Free Radic Biol Med (2005) 0.91
Titin and diaphragm dysfunction in mechanically ventilated rats. Intensive Care Med (2012) 0.90
Time course of diaphragm function recovery after controlled mechanical ventilation in rats. J Appl Physiol (1985) (2013) 0.90
Inspiratory muscle training improves maximal inspiratory pressure and may assist weaning in older intubated patients: a randomised trial. J Physiother (2010) 0.89
Impact of IL-10 on diaphragmatic cytokine expression and contractility during Pseudomonas Infection. Am J Respir Cell Mol Biol (2006) 0.88
EMD 57033 partially reverses ventilator-induced diaphragm muscle fibre calcium desensitisation. Pflugers Arch (2009) 0.86
Diaphragm fiber strength is reduced in critically ill patients and restored by a troponin activator. Am J Respir Crit Care Med (2014) 0.85
Inspiratory muscle training did not accelerate weaning from mechanical ventilation but did improve tidal volume and maximal respiratory pressures: a randomised trial. J Physiother (2013) 0.84
Acute effects of high-dose methylprednisolone on diaphragm muscle function. Muscle Nerve (2008) 0.84
Is there a role for growth hormone therapy in refractory critical illness? Curr Opin Crit Care (2008) 0.84
Sepsis is associated with a preferential diaphragmatic atrophy: a critically ill patient study using tridimensional computed tomography. Anesthesiology (2014) 0.83
Action of GH on skeletal muscle function: molecular and metabolic mechanisms. J Mol Endocrinol (2013) 0.82
Effects of controlled mechanical ventilation on sepsis-induced diaphragm dysfunction in rats. Crit Care Med (2014) 0.82
Muscle-specific inhibition of the classical nuclear factor-κB pathway is protective against diaphragmatic weakness in murine endotoxemia. Crit Care Med (2014) 0.81
Identification of prolonged phrenic nerve conduction time in the ICU: magnetic versus electrical stimulation. Intensive Care Med (2011) 0.80
Does inspiratory muscle dysfunction predict readmission after intensive care unit discharge? Am J Respir Crit Care Med (2014) 0.79
Multimodal nutrition/anabolic therapy for wasting conditions. Curr Opin Clin Nutr Metab Care (2014) 0.78
Inspiratory muscle training facilitates weaning from mechanical ventilation among patients in the intensive care unit: a systematic review. J Physiother (2015) 0.78
Monitoring and preventing diaphragm injury. Curr Opin Crit Care (2015) 0.77
Corticosteroid effects on ventilator-induced diaphragm dysfunction in anesthetized rats depend on the dose administered. Respir Res (2010) 0.77
Assessment of patient-ventilator breath contribution during neurally adjusted ventilatory assist in patients with acute respiratory failure. Crit Care (2015) 0.77