Published in Med Chem on January 01, 2016
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Identification of acquired antimicrobial resistance genes. J Antimicrob Chemother (2012) 13.77
Multilocus sequence typing of total-genome-sequenced bacteria. J Clin Microbiol (2012) 8.15
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
The immune epitope database and analysis resource: from vision to blueprint. PLoS Biol (2005) 7.40
Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature (2010) 6.26
Reliable prediction of T-cell epitopes using neural networks with novel sequence representations. Protein Sci (2003) 5.94
A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature (2004) 5.24
An Aboriginal Australian genome reveals separate human dispersals into Asia. Science (2011) 4.84
Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway. Nat Cell Biol (2008) 4.68
NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11. Nucleic Acids Res (2008) 4.53
Improved method for predicting linear B-cell epitopes. Immunome Res (2006) 4.32
NetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and -B locus protein of known sequence. PLoS One (2007) 3.99
Real-time whole-genome sequencing for routine typing, surveillance, and outbreak detection of verotoxigenic Escherichia coli. J Clin Microbiol (2014) 3.75
A community resource benchmarking predictions of peptide binding to MHC-I molecules. PLoS Comput Biol (2006) 3.73
Improved prediction of MHC class I and class II epitopes using a novel Gibbs sampling approach. Bioinformatics (2004) 3.72
NetMHCpan, a method for MHC class I binding prediction beyond humans. Immunogenetics (2008) 3.59
Prediction of residues in discontinuous B-cell epitopes using protein 3D structures. Protein Sci (2006) 3.06
The design and implementation of the immune epitope database and analysis resource. Immunogenetics (2005) 3.00
Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1. Nat Immunol (2008) 2.89
Draft genome of the wheat A-genome progenitor Triticum urartu. Nature (2013) 2.86
Prediction of MHC class II binding affinity using SMM-align, a novel stabilization matrix alignment method. BMC Bioinformatics (2007) 2.83
Accurate approximation method for prediction of class I MHC affinities for peptides of length 8, 10 and 11 using prediction tools trained on 9mers. Bioinformatics (2008) 2.69
The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition. Clin Cancer Res (2012) 2.63
Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin. Endocrinology (2003) 2.56
Gigantic enhancement in response and reset time of ZnO UV nanosensor by utilizing Schottky contact and surface functionalization. Appl Phys Lett (2009) 2.54
Peptide binding predictions for HLA DR, DP and DQ molecules. BMC Bioinformatics (2010) 2.53
NN-align. An artificial neural network-based alignment algorithm for MHC class II peptide binding prediction. BMC Bioinformatics (2009) 2.50
Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan. PLoS Comput Biol (2008) 2.48
The role of the proteasome in generating cytotoxic T-cell epitopes: insights obtained from improved predictions of proteasomal cleavage. Immunogenetics (2005) 2.40
Selection of reliable reference genes for gene expression studies in peach using real-time PCR. BMC Mol Biol (2009) 2.35
Genotyping using whole-genome sequencing is a realistic alternative to surveillance based on phenotypic antimicrobial susceptibility testing. J Antimicrob Chemother (2012) 2.23
Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus. Nature (2005) 2.23
An integrative approach to CTL epitope prediction: a combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions. Eur J Immunol (2005) 2.19
Immune epitope database analysis resource (IEDB-AR). Nucleic Acids Res (2008) 2.14
Immune epitope database analysis resource. Nucleic Acids Res (2012) 2.09
Large-scale validation of methods for cytotoxic T-lymphocyte epitope prediction. BMC Bioinformatics (2007) 2.05
miR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: An essential role for apoptosis. J Hepatol (2009) 2.03
Towards a consensus on datasets and evaluation metrics for developing B-cell epitope prediction tools. J Mol Recognit (2007) 2.02
Cellular uptake, intracellular trafficking, and cytotoxicity of nanomaterials. Small (2011) 2.00
Molecular imaging of interstitial alterations in remodeling myocardium after myocardial infarction. J Am Coll Cardiol (2008) 1.97
PathogenFinder--distinguishing friend from foe using bacterial whole genome sequence data. PLoS One (2013) 1.97
Modeling the adaptive immune system: predictions and simulations. Bioinformatics (2007) 1.95
CPHmodels-3.0--remote homology modeling using structure-guided sequence profiles. Nucleic Acids Res (2010) 1.94
Rapid whole-genome sequencing for detection and characterization of microorganisms directly from clinical samples. J Clin Microbiol (2013) 1.86
Ten years of bacterial genome sequencing: comparative-genomics-based discoveries. Funct Integr Genomics (2006) 1.86
Modulating angiogenesis: the yin and the yang in ginseng. Circulation (2004) 1.86
Modulation of T-cell activation by malignant melanoma initiating cells. Cancer Res (2010) 1.83
SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production. Immunity (2006) 1.79
NetMHCIIpan-2.0 - Improved pan-specific HLA-DR predictions using a novel concurrent alignment and weight optimization training procedure. Immunome Res (2010) 1.78
Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses. J Immunol (2009) 1.77
Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration. PLoS Pathog (2006) 1.76
Human recombinant erythropoietin augments serum asymmetric dimethylarginine concentrations but does not compromise nitric oxide generation in mice. Nephrol Dial Transplant (2008) 1.75
Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease. J Biol Chem (2011) 1.75
v-SNAREs control exocytosis of vesicles from priming to fusion. EMBO J (2005) 1.75
Imatinib targeting of KIT-mutant oncoprotein in melanoma. Clin Cancer Res (2008) 1.73
MHC class II epitope predictive algorithms. Immunology (2010) 1.72
Piezoelectric field effect transistor and nanoforce sensor based on a single ZnO nanowire. Nano Lett (2006) 1.72
A role for the beta-catenin/T-cell factor signaling cascade in vascular remodeling. Circ Res (2002) 1.72
Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release. Kidney Int (2013) 1.71
CTL epitopes for influenza A including the H5N1 bird flu; genome-, pathogen-, and HLA-wide screening. Vaccine (2006) 1.66
Effects of resistant starch, a non-digestible fermentable fiber, on reducing body fat. Obesity (Silver Spring) (2006) 1.66
Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease. J Neurosci (2004) 1.66
Dual molecular imaging for targeting metalloproteinase activity and apoptosis in atherosclerosis: molecular imaging facilitates understanding of pathogenesis. J Nucl Cardiol (2009) 1.60
Structural insight into epitopes in the pregnancy-associated malaria protein VAR2CSA. PLoS Pathog (2008) 1.60
Coating optimization of superparamagnetic iron oxide nanoparticles for high T2 relaxivity. Nano Lett (2010) 1.58
NetMHCcons: a consensus method for the major histocompatibility complex class I predictions. Immunogenetics (2011) 1.57
Human Kruppel-like factor 5 is a target of the E3 ubiquitin ligase WWP1 for proteolysis in epithelial cells. J Biol Chem (2005) 1.56
DNA microarray profiling to identify angiotensin-responsive genes in vascular smooth muscle cells: potential mediators of vascular disease. Circ Res (2003) 1.55
Down-regulated expression of SATB2 is associated with metastasis and poor prognosis in colorectal cancer. J Pathol (2009) 1.53
Benchmarking of methods for genomic taxonomy. J Clin Microbiol (2014) 1.51
Phosphatase of regenerating liver-3 promotes motility and metastasis of mouse melanoma cells. Am J Pathol (2004) 1.51
Use of arterially perfused rabbit ventricular wedge in predicting arrhythmogenic potentials of drugs. J Pharmacol Toxicol Methods (2006) 1.50
NetMHCIIpan-3.0, a common pan-specific MHC class II prediction method including all three human MHC class II isotypes, HLA-DR, HLA-DP and HLA-DQ. Immunogenetics (2013) 1.49
Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter. Mol Cell Biol (2008) 1.48
L-type calcium current recovery versus ventricular repolarization: preserved membrane-stabilizing mechanism for different QT intervals across species. Heart Rhythm (2007) 1.48
The angiosuppressive effects of 20(R)- ginsenoside Rg3. Biochem Pharmacol (2006) 1.47
Risk factors for predicting postoperative complications after open infrarenal abdominal aortic aneurysm repair: results from a single vascular center in China. J Clin Anesth (2013) 1.46
Location of the antidepressant binding site in the serotonin transporter: importance of Ser-438 in recognition of citalopram and tricyclic antidepressants. J Biol Chem (2009) 1.46
Meta-analysis on the possible association between in vitro fertilization and cancer risk. Int J Gynecol Cancer (2013) 1.46
Integrating genome-based informatics to modernize global disease monitoring, information sharing, and response. Emerg Infect Dis (2012) 1.45
Increased polycomb-group oncogene Bmi-1 expression correlates with poor prognosis in hepatocellular carcinoma. J Cancer Res Clin Oncol (2007) 1.44
Reliable B cell epitope predictions: impacts of method development and improved benchmarking. PLoS Comput Biol (2012) 1.44
RXR is an essential component of the oncogenic PML/RARA complex in vivo. Cancer Cell (2007) 1.43
Rhinovirus disrupts the barrier function of polarized airway epithelial cells. Am J Respir Crit Care Med (2008) 1.43
Cubilin and amnionless mediate protein reabsorption in Drosophila nephrocytes. J Am Soc Nephrol (2012) 1.42
High-strain sensors based on ZnO nanowire/polystyrene hybridized flexible films. Adv Mater (2011) 1.41
Local delivery of pravastatin inhibits intimal formation in a mouse vein graft model. Can J Cardiol (2012) 1.40
Gastric mucosal recognition of Helicobacter pylori is independent of Toll-like receptor 4. J Infect Dis (2003) 1.39
The tumor suppressor CYLD regulates microtubule dynamics and plays a role in cell migration. J Biol Chem (2008) 1.39
Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenance. Blood (2007) 1.39
Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells. Cancer Res (2008) 1.39
Flexible solid-state supercapacitors based on carbon nanoparticles/MnO2 nanorods hybrid structure. ACS Nano (2011) 1.39
Overexpression of cannabinoid receptors CB1 and CB2 correlates with improved prognosis of patients with hepatocellular carcinoma. Cancer Genet Cytogenet (2006) 1.38
Experimental validation of a three-dimensional linear system model for breast tomosynthesis. Med Phys (2009) 1.37
Rhinovirus infection of allergen-sensitized and -challenged mice induces eotaxin release from functionally polarized macrophages. J Immunol (2010) 1.37