Regulatory T Cells Contribute to the Inhibition of Radiation-Induced Acute Lung Inflammation via Bee Venom Phospholipase A₂ in Mice.

PubWeight™: 0.77‹?›

🔗 View Article (PMID 27144583)

Published in Toxins (Basel) on April 30, 2016

Authors

Dasom Shin1, Gihyun Lee2, Sung-Hwa Sohn3, Soojin Park4, Kyung-Hwa Jung5, Ji Min Lee6, Jieun Yang7, Jaeho Cho8, Hyunsu Bae9

Author Affiliations

1: Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul 130-701, South Korea. ssd060@naver.com.
2: Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul 130-701, South Korea. glee@khu.ac.kr.
3: Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 120-752, South Korea. 19980769@hanmail.net.
4: Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul 130-701, South Korea. ih_sj@naver.com.
5: Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul 130-701, South Korea. jhkh242@naver.com.
6: Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 120-752, South Korea. carol114@yuhs.ac.
7: Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul 130-701, South Korea. yje2020@hanmail.net.
8: Department of Radiation Oncology, Yonsei University College of Medicine, Seoul 120-752, South Korea. jjhmd@yuhs.ac.
9: Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul 130-701, South Korea. hbae@khu.ac.kr.

Articles cited by this

Transforming growth factor-beta regulation of immune responses. Annu Rev Immunol (2006) 9.53

IL-13 effector functions. Annu Rev Immunol (2001) 5.51

An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease. Am J Respir Crit Care Med (2012) 5.37

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature (1997) 5.35

Phospholipase A2 structure/function, mechanism, and signaling. J Lipid Res (2008) 3.46

Effectiveness of acupuncture and bee venom acupuncture in idiopathic Parkinson's disease. Parkinsonism Relat Disord (2012) 3.44

Use of plasma biomarkers at exacerbation of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2006) 2.80

Identification of a monocyte specific pre-interleukin 1 beta convertase activity. Proc Natl Acad Sci U S A (1989) 2.73

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature (2009) 2.59

Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells. J Immunol (2005) 2.48

Radiation pneumonitis and fibrosis: mechanisms underlying its pathogenesis and implications for future research. Int J Radiat Oncol Biol Phys (2006) 2.34

Control of autoimmunity by naturally arising regulatory CD4+ T cells. Adv Immunol (2003) 2.28

COX-2-derived prostacyclin protects against bleomycin-induced pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2006) 2.27

The bee venom test: a new tonic-pain test. Pain (1996) 2.24

Inflammatory markers are associated with ventilatory limitation and muscle dysfunction in obstructive lung disease in well functioning elderly subjects. Thorax (2005) 2.08

Effect of interactions between lower airway bacterial and rhinoviral infection in exacerbations of COPD. Chest (2006) 2.06

C-reactive protein levels and survival in patients with moderate to very severe COPD. Chest (2008) 1.98

Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity. Immunity (2013) 1.88

Radiation-induced lung injury. Semin Radiat Oncol (2003) 1.82

Systemic and upper and lower airway inflammation at exacerbation of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2005) 1.75

Cancer and inflammation: promise for biologic therapy. J Immunother (2010) 1.72

Infectious disease, the innate immune response, and fibrosis. J Clin Invest (2007) 1.68

Stereotactic body radiation therapy for patients with lung cancer previously treated with thoracic radiation. Int J Radiat Oncol Biol Phys (2010) 1.58

Global impairment of CD4+CD25+FOXP3+ regulatory T cells in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2009) 1.51

Airway hyperresponsiveness and airway obstruction in transgenic mice. Morphologic correlates in mice overexpressing interleukin (IL)-11 and IL-6 in the lung. Am J Respir Cell Mol Biol (2000) 1.51

Radiation pulmonary toxicity: from mechanisms to management. Semin Radiat Oncol (2010) 1.43

NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages. J Biol Chem (2004) 1.33

Multipotent stromal cells induce human regulatory T cells through a novel pathway involving skewing of monocytes toward anti-inflammatory macrophages. Stem Cells (2013) 1.31

Epitope-specific T cell tolerance to phospholipase A2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro. J Clin Invest (1996) 1.29

Anti-cancer effect of bee venom in prostate cancer cells through activation of caspase pathway via inactivation of NF-κB. Prostate (2010) 1.23

The nociceptive and anti-nociceptive effects of bee venom injection and therapy: a double-edged sword. Prog Neurobiol (2010) 1.23

Dietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice. Radiat Res (2010) 1.22

Significance of the balance between regulatory T (Treg) and T helper 17 (Th17) cells during hepatitis B virus related liver fibrosis. PLoS One (2012) 1.20

Links between innate immunity and normal tissue radiobiology. Radiat Res (2010) 1.19

Pathogenesis of systemic sclerosis: altered B cell function is the key linking systemic autoimmunity and tissue fibrosis. J Dermatol Sci (2005) 1.19

Changes in plasma TGF beta levels during pulmonary radiotherapy as a predictor of the risk of developing radiation pneumonitis. Int J Radiat Oncol Biol Phys (1994) 1.19

Caspase-1 has both proinflammatory and regulatory properties in Helicobacter infections, which are differentially mediated by its substrates IL-1β and IL-18. J Immunol (2012) 1.19

Stereotactic body radiation therapy for lung cancer. Chest (2013) 1.12

cAMP and Epac in the regulation of tissue fibrosis. Br J Pharmacol (2012) 1.04

A phase I study of the safety of honeybee venom extract as a possible treatment for patients with progressive forms of multiple sclerosis. Allergy Asthma Proc (2006) 1.02

Overexpression of the mammalian target of rapamycin: a novel biomarker for poor survival in resected early stage non-small cell lung cancer. J Thorac Oncol (2010) 1.01

Stereotactic body radiation therapy for stage I non-small-cell lung cancer: a historical overview of clinical studies. Jpn J Clin Oncol (2013) 1.01

Anti-inflammatory cytokines: important immunoregulatory factors contributing to chemotherapy-induced gastrointestinal mucositis. Chemother Res Pract (2012) 0.95

Inflammatory monocytes are potent antitumor effectors controlled by regulatory CD4+ T cells. Proc Natl Acad Sci U S A (2013) 0.95

Venom therapy in multiple sclerosis. Neuropharmacology (2007) 0.94

Secretory phospholipase A2-IID is an effector molecule of CD4+CD25+ regulatory T cells. Proc Natl Acad Sci U S A (2009) 0.93

Phospholipase A2 inhibits cisplatin-induced acute kidney injury by modulating regulatory T cells by the CD206 mannose receptor. Kidney Int (2015) 0.92

Development of a small animal model to simulate clinical stereotactic body radiotherapy-induced central and peripheral lung injuries. J Radiat Res (2014) 0.91

Immunotherapy of allergy: anergy, deletion, and immune deviation. Curr Opin Immunol (1998) 0.91

Bee venom ameliorates ovalbumin induced allergic asthma via modulating CD4+CD25+ regulatory T cells in mice. Cytokine (2012) 0.90

Bee Venom Mitigates Cisplatin-Induced Nephrotoxicity by Regulating CD4(+)CD25(+)Foxp3(+) Regulatory T Cells in Mice. Evid Based Complement Alternat Med (2013) 0.89

Active site of bee venom phospholipase A2: the role of histidine-34, aspartate-64 and tyrosine-87. Biochemistry (1996) 0.89

Bee Venom Phospholipase A₂: Yesterday's Enemy Becomes Today's Friend. Toxins (Basel) (2016) 0.88

Bee Venom Phospholipase A2, a Novel Foxp3+ Regulatory T Cell Inducer, Protects Dopaminergic Neurons by Modulating Neuroinflammatory Responses in a Mouse Model of Parkinson's Disease. J Immunol (2015) 0.88

Bee venom-associated Th1/Th2 immunoglobulin class switching results in immune tolerance of NZB/W F1 murine lupus nephritis. Am J Nephrol (2011) 0.87

CD4+CD25+FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung. Front Pharmacol (2014) 0.84

Transfer of CD4+ T cells to C.B-17 SCID mice: a model to study Th1 and Th2 cell differentiation and regulation in vivo. Res Immunol (1994) 0.84

Catechins and Sialic Acid Attenuate Helicobacter pylori-Triggered Epithelial Caspase-1 Activity and Eradicate Helicobacter pylori Infection. Evid Based Complement Alternat Med (2013) 0.84

Bee venom phospholipase A2 suppresses allergic airway inflammation in an ovalbumin-induced asthma model through the induction of regulatory T cells. Immun Inflamm Dis (2015) 0.83

The inflammasome accelerates radiation-induced lung inflammation and fibrosis in mice. Environ Toxicol Pharmacol (2015) 0.83

Bee venom injection produces a peripheral anti-inflammatory effect by activation of a nitric oxide-dependent spinocoeruleus pathway. Neurosci Lett (2007) 0.82

Acupuncture for cerebral vasospasm after subarachnoid hemorrhage: a retrospective case-control study. J Altern Complement Med (2012) 0.80

The effects of Gamijinhae-tang on elastase/lipopolysaccharide-induced lung inflammation in an animal model of acute lung injury. BMC Complement Altern Med (2013) 0.78