Maintenance of Stem Cell Niche Integrity by a Novel Activator of Integrin Signaling.

PubWeight™: 0.79‹?›

🔗 View Article (PMID 27191715)

Published in PLoS Genet on May 18, 2016

Authors

Joo Yeun Lee1,2, Jessica Y Chen1, Jillian L Shaw1,2, Karen T Chang1,2,3

Author Affiliations

1: Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
2: Neuroscience Graduate Program, University of Southern California, Los Angeles, California, United States of America.
3: Department of Cell and Neurobiology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

Articles cited by this

Integrins: bidirectional, allosteric signaling machines. Cell (2002) 36.25

Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol (2005) 11.74

Integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer (2010) 11.16

Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell (2008) 9.92

The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells (1978) 8.80

Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science (2003) 6.72

Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue. Science (2001) 5.12

Integrin ligands at a glance. J Cell Sci (2006) 4.76

Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling. Science (2001) 4.69

Regulation of zygotic gene expression in Drosophila primordial germ cells. Curr Biol (1998) 4.53

The cell-cell adhesion molecule E-cadherin. Cell Mol Life Sci (2008) 3.77

No place like home: anatomy and function of the stem cell niche. Nat Rev Mol Cell Biol (2008) 3.46

Germline stem cells anchored by adherens junctions in the Drosophila ovary niches. Science (2002) 3.42

Male and female Drosophila germline stem cells: two versions of immortality. Science (2007) 3.31

Integrin signalling at a glance. J Cell Sci (2009) 3.28

Integrin-dependent anchoring of a stem-cell niche. Nat Cell Biol (2007) 2.59

Integrin structure, activation, and interactions. Cold Spring Harb Perspect Biol (2011) 2.58

Decline in self-renewal factors contributes to aging of the stem cell niche in the Drosophila testis. Cell Stem Cell (2007) 2.53

Gbb/Bmp signaling is essential for maintaining germline stem cells and for repressing bam transcription in the Drosophila testis. Development (2004) 2.35

Differentiation-defective stem cells outcompete normal stem cells for niche occupancy in the Drosophila ovary. Cell Stem Cell (2008) 2.32

Germline self-renewal requires cyst stem cells and stat regulates niche adhesion in Drosophila testes. Nat Cell Biol (2010) 2.29

Multipotent somatic stem cells contribute to the stem cell niche in the Drosophila testis. Nature (2008) 2.27

The function of PS integrins during Drosophila embryogenesis. Cell (1989) 2.19

The germinal proliferation center in the testis of Drosophila melanogaster. J Ultrastruct Res (1979) 2.16

Drosophila stem cell niches: a decade of discovery suggests a unified view of stem cell regulation. Dev Cell (2011) 2.10

Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. Cell Stress Chaperones (2000) 1.91

Rescue of the Drosophila phototransduction mutation trp by germline transformation. Science (1985) 1.85

JAK-STAT signal inhibition regulates competition in the Drosophila testis stem cell niche. Science (2009) 1.81

Signaling from germ cells mediated by the rhomboid homolog stet organizes encapsulation by somatic support cells. Development (2002) 1.70

Signaling in stem cell niches: lessons from the Drosophila germline. J Cell Sci (2005) 1.69

Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis. Semin Cell Dev Biol (1998) 1.68

The stem cell niche: lessons from the Drosophila testis. Development (2011) 1.67

ERdj3, a stress-inducible endoplasmic reticulum DnaJ homologue, serves as a cofactor for BiP's interactions with unfolded substrates. Mol Biol Cell (2004) 1.66

Development of the male germline stem cell niche in Drosophila. Dev Biol (2006) 1.55

Germline stem cells. Cold Spring Harb Perspect Biol (2011) 1.53

Analysis of twenty-four Gal4 lines in Drosophila melanogaster. Genesis (2002) 1.51

HEDJ, an Hsp40 co-chaperone localized to the endoplasmic reticulum of human cells. J Biol Chem (2000) 1.50

E-cadherin is required for centrosome and spindle orientation in Drosophila male germline stem cells. PLoS One (2010) 1.43

Integrins as mediators of morphogenesis in Drosophila. Dev Biol (2000) 1.42

Large scale screen for transposon insertions into cloned genes. Proc Natl Acad Sci U S A (1991) 1.38

Adhesion in the stem cell niche: biological roles and regulation. Development (2013) 1.30

Rap-GEF signaling controls stem cell anchoring to their niche through regulating DE-cadherin-mediated cell adhesion in the Drosophila testis. Dev Cell (2006) 1.27

Drosophila E-cadherin is essential for proper germ cell-soma interaction during gonad morphogenesis. Development (2003) 1.15

Drosophila PS2 integrin mediates RGD-dependent cell-matrix interactions. Development (1992) 1.10

A role for PS integrins in morphological growth and synaptic function at the postembryonic neuromuscular junction of Drosophila. Development (1999) 1.07

Local BMP receptor activation at adherens junctions in the Drosophila germline stem cell niche. Nat Commun (2011) 1.06

magu is required for germline stem cell self-renewal through BMP signaling in the Drosophila testis. Dev Biol (2011) 1.05

Germline stem cells: origin and destiny. Cell Stem Cell (2012) 1.04

Hedgehog is required for CySC self-renewal but does not contribute to the GSC niche in the Drosophila testis. Development (2012) 1.03

lines and bowl affect the specification of cyst stem cells and niche cells in the Drosophila testis. Development (2011) 1.02

Neutral competition of stem cells is skewed by proliferative changes downstream of Hh and Hpo. EMBO J (2014) 1.01

Dual fluorescence detection of protein and RNA in Drosophila tissues. Nat Protoc (2012) 0.98

Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis. EMBO J (2014) 0.96

Protogenin defines a transition stage during embryonic neurogenesis and prevents precocious neuronal differentiation. J Neurosci (2010) 0.95

Cell adhesion in Drosophila: versatility of cadherin and integrin complexes during development. Curr Opin Cell Biol (2012) 0.94

Lasp anchors the Drosophila male stem cell niche and mediates spermatid individualization. Mech Dev (2008) 0.92

The receptor tyrosine phosphatase Lar regulates adhesion between Drosophila male germline stem cells and the niche. Development (2012) 0.90

TGFbeta receptor saxophone non-autonomously regulates germline proliferation in a Smox/dSmad2-dependent manner in Drosophila testis. Dev Biol (2007) 0.89

Disintegrins: integrin selective ligands which activate integrin-coupled signaling and modulate leukocyte functions. Braz J Med Biol Res (2005) 0.89

JAK/STAT signaling regulates tissue outgrowth and male germline stem cell fate in Drosophila. Cell Res (2005) 0.87

discs large regulates somatic cyst cell survival and expansion in Drosophila testis. Cell Res (2009) 0.87

Stem cells: what can we learn from flies? Fly (Austin) (2011) 0.86

Histone demethylase dUTX antagonizes JAK-STAT signaling to maintain proper gene expression and architecture of the Drosophila testis niche. Development (2013) 0.86

ERdj3 regulates BiP occupancy in living cells. J Cell Sci (2013) 0.85

Functions of the Drosophila JAK-STAT pathway: Lessons from stem cells. JAKSTAT (2012) 0.81

The Hox gene Abd-B controls stem cell niche function in the Drosophila testis. Dev Cell (2014) 0.80

Dynein light chain 1 functions in somatic cyst cells regulate spermatogonial divisions in Drosophila. Sci Rep (2011) 0.80

Secretome profiling of primary cells reveals that THBS2 is a salivary biomarker of oral cavity squamous cell carcinoma. J Proteome Res (2014) 0.79

Socs36E Controls Niche Competition by Repressing MAPK Signaling in the Drosophila Testis. PLoS Genet (2016) 0.78

Protogenin prevents premature apoptosis of rostral cephalic neural crest cells by activating the α5β1-integrin. Cell Death Dis (2013) 0.78

Identification and characterization of endonuclein binding proteins: evidence of modulatory effects on signal transduction and chaperone activity. BMC Biochem (2009) 0.77

Anchoring stem cells in the niche by cell adhesion molecules. Cell Adh Migr (2009) 0.76