| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing.
|
Nat Genet
|
2008
|
43.63
|
|
2
|
A comprehensive catalogue of somatic mutations from a human cancer genome.
|
Nature
|
2009
|
24.27
|
|
3
|
A small-cell lung cancer genome with complex signatures of tobacco exposure.
|
Nature
|
2009
|
18.39
|
|
4
|
A large genome center's improvements to the Illumina sequencing system.
|
Nat Methods
|
2008
|
15.56
|
|
5
|
The patterns and dynamics of genomic instability in metastatic pancreatic cancer.
|
Nature
|
2010
|
12.43
|
|
6
|
Mutational processes molding the genomes of 21 breast cancers.
|
Cell
|
2012
|
11.22
|
|
7
|
The life history of 21 breast cancers.
|
Cell
|
2012
|
10.59
|
|
8
|
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing.
|
Nat Biotechnol
|
2013
|
7.97
|
|
9
|
Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing.
|
Proc Natl Acad Sci U S A
|
2008
|
7.22
|
|
10
|
Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies.
|
Nat Med
|
2012
|
6.77
|
|
11
|
Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity.
|
Eur Urol
|
2012
|
2.39
|
|
12
|
Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors.
|
Genes Chromosomes Cancer
|
2010
|
2.11
|
|
13
|
Next-generation sequencing reveals high concordance of recurrent somatic alterations between primary tumor and metastases from patients with non-small-cell lung cancer.
|
J Clin Oncol
|
2013
|
1.71
|
|
14
|
Next-generation sequencing identifies and immunohistochemistry confirms a novel crizotinib-sensitive ALK rearrangement in a patient with metastatic non-small-cell lung cancer.
|
J Thorac Oncol
|
2012
|
1.66
|
|
15
|
BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition.
|
Clin Cancer Res
|
2013
|
1.66
|
|
16
|
New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing.
|
Oncologist
|
2014
|
1.61
|
|
17
|
Concordance of genomic alterations between primary and recurrent breast cancer.
|
Mol Cancer Ther
|
2014
|
1.57
|
|
18
|
Targeted genomic sequencing of pediatric Burkitt lymphoma identifies recurrent alterations in antiapoptotic and chromatin-remodeling genes.
|
Blood
|
2012
|
1.38
|
|
19
|
Clinical next-generation sequencing successfully applied to fine-needle aspirations of pulmonary and pancreatic neoplasms.
|
Cancer Cytopathol
|
2013
|
1.16
|
|
20
|
Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.
|
Acta Neuropathol
|
2013
|
1.15
|
|
21
|
Relapsed classic E-cadherin (CDH1)-mutated invasive lobular breast cancer shows a high frequency of HER2 (ERBB2) gene mutations.
|
Clin Cancer Res
|
2013
|
1.14
|
|
22
|
A high frequency of activating extracellular domain ERBB2 (HER2) mutation in micropapillary urothelial carcinoma.
|
Clin Cancer Res
|
2013
|
1.12
|
|
23
|
Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome.
|
PLoS One
|
2013
|
1.10
|
|
24
|
Novel chromosomal rearrangements and break points at the t(6;9) in salivary adenoid cystic carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome.
|
Clin Cancer Res
|
2011
|
1.05
|
|
25
|
Identification of a novel HIP1-ALK fusion variant in Non-Small-Cell Lung Cancer (NSCLC) and discovery of ALK I1171 (I1171N/S) mutations in two ALK-rearranged NSCLC patients with resistance to Alectinib.
|
J Thorac Oncol
|
2014
|
1.02
|
|
26
|
Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway.
|
Oncotarget
|
2014
|
0.95
|
|
27
|
Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies.
|
Am J Surg Pathol
|
2014
|
0.91
|
|
28
|
Thymoma patients treated in a phase I clinic at MD Anderson Cancer Center: responses to mTOR inhibitors and molecular analyses.
|
Oncotarget
|
2013
|
0.89
|
|
29
|
Genomic profiling of advanced-stage, metaplastic breast carcinoma by next-generation sequencing reveals frequent, targetable genomic abnormalities and potential new treatment options.
|
Arch Pathol Lab Med
|
2015
|
0.89
|
|
30
|
Calcium channel antagonists discovered by a multidisciplinary approach.
|
J Med Chem
|
2006
|
0.85
|
|
31
|
Evaluation of a Congenital Infantile Fibrosarcoma by Comprehensive Genomic Profiling Reveals an LMNA-NTRK1 Gene Fusion Responsive to Crizotinib.
|
J Natl Cancer Inst
|
2015
|
0.83
|
|
32
|
Activity of c-Met/ALK Inhibitor Crizotinib and Multi-Kinase VEGF Inhibitor Pazopanib in Metastatic Gastrointestinal Neuroectodermal Tumor Harboring EWSR1-CREB1 Fusion.
|
Oncology
|
2016
|
0.80
|
|
33
|
Prismatomerin, a new iridoid from Prismatomeris tetrandra. Structure elucidation, determination of absolute configuration, and cytotoxicity.
|
J Nat Prod
|
2007
|
0.77
|
|
34
|
Stereoselective behavior of the functional diltiazem analogue 1-[(4-chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a new L-type calcium channel blocker.
|
J Med Chem
|
2009
|
0.76
|
|
35
|
Comparison of time-dependent density-functional theory and coupled cluster theory for the calculation of the optical rotations of chiral molecules.
|
J Phys Chem A
|
2008
|
0.76
|
|
36
|
Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma.
|
Oncology
|
2016
|
0.75
|
|
37
|
Synthesis, chromatographic separation, vibrational circular dichroism spectroscopy, and ab initio DFT studies of chiral thiepane tetraol derivatives.
|
J Org Chem
|
2005
|
0.75
|
|
38
|
Electronic circular dichroism of monomethyl [16O,17O,18O]-phosphate and [16O,17O,18O]-thiophosphate revisited.
|
Bioorg Chem
|
2009
|
0.75
|
|
39
|
Case Report: Immune-mediated Complete Response in a Patient With Recurrent Advanced Ewing Sarcoma (EWS) After Vigil Immunotherapy.
|
J Pediatr Hematol Oncol
|
2017
|
0.75
|
|
40
|
Determination of the absolute configuration of the natural product Klaivanolide via density functional calculations of vibrational circular dichroism (VCD).
|
Chirality
|
2009
|
0.75
|
|
41
|
Efficient Thia-bridged triarylamine heterohelicenes: synthesis, resolution, and absolute configuration determination.
|
Chemistry
|
2008
|
0.75
|
|
42
|
Absolute configuration assignment of norcamphor-derived furyl hydroperoxide using density functional theory calculations of optical rotation and vibrational circular dichroism.
|
J Org Chem
|
2010
|
0.75
|
|
43
|
Determination of the absolute configuration of the sex pheromone of the obscure mealybug by vibrational circular dichroism analysis.
|
Chem Commun (Camb)
|
2008
|
0.75
|
|
44
|
Next-Generation Sequencing Reveals Pathway Activations and New Routes to Targeted Therapies in Cutaneous Metastatic Melanoma.
|
Am J Dermatopathol
|
2017
|
0.75
|