Immunological Evasion in Glioblastoma.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27294132)

Published in Biomed Res Int on May 15, 2016

Authors

Roxana Magaña-Maldonado1, Elda Georgina Chávez-Cortez1, Nora Karen Olascoaga-Arellano1, Mariana López-Mejía1, Fernando Manuel Maldonado-Leal1, Julio Sotelo1, Benjamín Pineda1

Author Affiliations

1: Neuroimmunology and Neurooncology Unit, The National Institute of Neurology and Neurosurgery (NINN), Insurgentes Sur 3877, 14269 Mexico City, DF, Mexico.

Articles cited by this

Cancer statistics, 2013. CA Cancer J Clin (2013) 84.72

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med (2005) 74.55

The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol (2007) 49.11

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science (2005) 14.43

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature (1998) 11.61

FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell (2006) 9.24

Brain tumors. N Engl J Med (2001) 8.13

Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma. Nat Med (2006) 7.10

Natural innate and adaptive immunity to cancer. Annu Rev Immunol (2011) 7.09

Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. J Clin Oncol (2007) 6.68

Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion. Cancer Res (2005) 6.66

Immunogenic cell death in cancer therapy. Annu Rev Immunol (2012) 6.59

Antigen presentation and T cell stimulation by dendritic cells. Annu Rev Immunol (2001) 6.20

Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients. Clin Cancer Res (2009) 5.10

Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives. Immunol Rev (2008) 4.40

Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism. J Immunol (2002) 3.56

Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma. Cancer Res (2006) 3.02

Functional anatomy of T cell activation and synapse formation. Annu Rev Immunol (2010) 3.01

Factors influencing survival in high-grade gliomas. Semin Oncol (2003) 2.93

Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics. J Leukoc Biol (2008) 2.76

STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells. FASEB J (2005) 2.60

HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene (2005) 2.53

The role of microglia and macrophages in the pathophysiology of the CNS. Prog Neurobiol (1999) 2.46

Antiangiogenic therapies for high-grade glioma. Nat Rev Neurol (2009) 2.29

Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. Int J Radiat Oncol Biol Phys (2013) 2.28

Microglia function in brain tumors. J Neurosci Res (2005) 2.18

Incidence and prognostic impact of FoxP3+ regulatory T cells in human gliomas. Clin Cancer Res (2008) 2.15

Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma. Neuro Oncol (2011) 2.13

Role of macrophages in tumour progression. Immunol Lett (2009) 2.07

IDO and tolerance to tumors. Trends Mol Med (2004) 2.03

Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties. Neuro Oncol (2009) 1.80

Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion. Proc Natl Acad Sci U S A (2009) 1.79

Prolongation of survival following depletion of CD4+CD25+ regulatory T cells in mice with experimental brain tumors. J Neurosurg (2006) 1.73

Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy. Cancer Immunol Immunother (2007) 1.70

Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha. Eur J Immunol (2008) 1.69

The brain tumor microenvironment. Glia (2012) 1.66

The molecular signature of tissue resident memory CD8 T cells isolated from the brain. J Immunol (2012) 1.66

Hematopoiesis and suppressor bone marrow cells in mice bearing large metastatic Lewis lung carcinoma tumors. Cancer Res (1987) 1.59

IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival. Clin Cancer Res (2012) 1.55

Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans. Blood (2011) 1.54

Role of Stat3 in suppressing anti-tumor immunity. Curr Opin Immunol (2008) 1.52

Treg depletion inhibits efficacy of cancer immunotherapy: implications for clinical trials. PLoS One (2008) 1.49

miR-124 inhibits STAT3 signaling to enhance T cell-mediated immune clearance of glioma. Cancer Res (2013) 1.46

Mechanisms of malignant glioma immune resistance and sources of immunosuppression. Gene Ther Mol Biol (2006) 1.43

Functional maturation of adult mouse resting microglia into an APC is promoted by granulocyte-macrophage colony-stimulating factor and interaction with Th1 cells. J Immunol (2000) 1.33

Human leukocyte antigen and antigen processing machinery component defects in astrocytic tumors. Clin Cancer Res (2005) 1.32

Astrocytic regulation of human monocytic/microglial activation. J Immunol (2008) 1.32

T cells traffic from brain to cervical lymph nodes via the cribroid plate and the nasal mucosa. J Leukoc Biol (2006) 1.30

Cytokine and cytokine receptor mRNA expression in human glioblastomas: evidence of Th1, Th2 and Th3 cytokine dysregulation. Acta Neuropathol (2001) 1.23

Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice. Glia (2009) 1.21

The role of regulatory T cells in malignant glioma. Anticancer Res (2008) 1.18

Hypoxia potentiates glioma-mediated immunosuppression. PLoS One (2011) 1.17

Monocyte subpopulations in human gliomas: expression of Fc and complement receptors and correlation with tumor proliferation. Acta Neuropathol (1990) 1.14

Carbon nanotubes enhance CpG uptake and potentiate antiglioma immunity. Clin Cancer Res (2010) 1.14

Invariant natural killer T cells are preserved in patients with glioma and exhibit antitumor lytic activity following dendritic cell-mediated expansion. Int J Cancer (2004) 1.13

Tumor-infiltrating, myeloid-derived suppressor cells inhibit T cell activity by nitric oxide production in an intracranial rat glioma + vaccination model. J Neuroimmunol (2010) 1.08

A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma. PLoS One (2012) 1.08

Immunofluorescence study of lymphocytic infiltration in gliomas. Identification of T-lymphocytes. J Neurol Sci (1977) 1.04

Recent developments on immunotherapy for brain cancer. Expert Opin Emerg Drugs (2012) 1.03

Chronic effects of gamma-interferon on quinolinic acid and indoleamine-2,3-dioxygenase in brain of C57BL6 mice. Brain Res (1991) 1.01

Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation. J Neuroimmunol (2008) 1.00

Sleeping beauty-mediated somatic mutagenesis implicates CSF1 in the formation of high-grade astrocytomas. Cancer Res (2010) 0.98

Nestin, PDGFRbeta, CXCL12 and VEGF in glioma patients: different profiles of (pro-angiogenic) molecule expression are related with tumor grade and may provide prognostic information. Cancer Biol Ther (2007) 0.97

Inflammatory leukocytes associated with increased immunosuppression by glioblastoma. J Neurosurg (1992) 0.96

TGF-β signaling and its targeting for glioma treatment. Am J Cancer Res (2015) 0.93

Prognostic impact of CD68 and kallikrein 6 in human glioma. Anticancer Res (2009) 0.93

Expression of Fas ligand by microglia: possible role in glioma immune evasion. J Neuroimmunol (2001) 0.92

Irradiated tumor cell vaccine for treatment of an established glioma. II. Expansion of myeloid suppressor cells that promote tumor progression. Cancer Immunol Immunother (2002) 0.88

Brain tumors in Mexico: characteristics and prognosis of glioblastoma. Surg Neurol (2000) 0.88

Depletion of myeloid-derived suppressor cells during interleukin-12 immunogene therapy does not confer a survival advantage in experimental malignant glioma. Cancer Gene Ther (2014) 0.87

Astrocytic tumors. Recent Results Cancer Res (2009) 0.87

Combating immunosuppression in glioma. Future Oncol (2008) 0.87

In situ detection of transforming growth factor-beta mRNA in experimental rat glioma and reactive glial cells. Neurosci Lett (1994) 0.86

Regulatory T cells move in when gliomas say "I Do". Clin Cancer Res (2012) 0.85

Imbalances in T cell subpopulations in human gliomas. J Neurosurg (1988) 0.84

Isolation and in vitro growth of glioma-infiltrating lymphocytes, and an analysis of their surface phenotypes. J Neurosurg (1988) 0.83

The role of regulatory T-cells in glioma immunology. Clin Neurol Neurosurg (2014) 0.83

Immunobiology of brain tumors. Adv Tech Stand Neurosurg (1990) 0.82

Adjuvant immunotherapy of C6 glioma in rats with pertussis toxin. J Cancer Res Clin Oncol (2011) 0.80

Concomitant treatment with pertussis toxin plus temozolomide increases the survival of rats bearing intracerebral RG2 glioma. J Cancer Res Clin Oncol (2013) 0.80

CD4+ T effector memory cell dysfunction is associated with the accumulation of granulocytic myeloid-derived suppressor cells in glioblastoma patients. Neuro Oncol (2015) 0.80

Activation of glioma cells generates immune tolerant NKT cells. J Biol Chem (2014) 0.79

Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors. Acta Neuropathol (2015) 0.78

RB mutation and RAS overexpression induce resistance to NK cell-mediated cytotoxicity in glioma cells. Cancer Cell Int (2015) 0.76

[Optical laser interventions on the anterior portion of the eye]. Vestn Oftalmol (1978) 0.76

Clinical-histopathologic concordance of tumors of the nervous system at the Manuel Velasco Suárez National Institute of Neurology and Neurosurgery in Mexico City. Arch Pathol Lab Med (2003) 0.75