MicroRNA-181b inhibits thrombin-mediated endothelial activation and arterial thrombosis by targeting caspase recruitment domain family member 10.

PubWeight™: 0.95‹?› | Rank: Top 15%

🔗 View Article (PMID 27297585)

Published in FASEB J on June 13, 2016

Authors

Jibin Lin1, Shaolin He2, Xinghui Sun3, Gregory Franck3, Yihuan Deng1, Dafeng Yang4, Stefan Haemmig3, A K M Wara3, Basak Icli3, Dazhu Li2, Mark W Feinberg5

Author Affiliations

1: Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Department of Cardiology, Institute of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; and.
2: Department of Cardiology, Institute of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; and.
3: Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA;
4: Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, China.
5: Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; mfeinberg@partners.org.

Articles cited by this

Thrombin signalling and protease-activated receptors. Nature (2000) 9.27

Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA (2003) 8.07

The molecular basis of blood coagulation. Cell (1988) 5.29

Mechanisms of thrombus formation. N Engl J Med (2008) 4.67

Protease-activated receptors in hemostasis, thrombosis and vascular biology. J Thromb Haemost (2005) 4.64

The IKK complex, a central regulator of NF-kappaB activation. Cold Spring Harb Perspect Biol (2010) 2.64

MicroRNA-181b regulates NF-κB-mediated vascular inflammation. J Clin Invest (2012) 2.24

Endothelial dysfunction: cardiovascular risk factors, therapy, and outcome. Vasc Health Risk Manag (2005) 2.15

Protease-activated receptors in cardiovascular diseases. Circulation (2006) 2.10

Systemic delivery of microRNA-181b inhibits nuclear factor-κB activation, vascular inflammation, and atherosclerosis in apolipoprotein E-deficient mice. Circ Res (2013) 2.01

Arterial thrombosis--insidious, unpredictable and deadly. Nat Med (2011) 1.96

Murine models of vascular thrombosis (Eitzman series). Arterioscler Thromb Vasc Biol (2007) 1.74

Intertwining of thrombosis and inflammation in atherosclerosis. Curr Opin Hematol (2007) 1.63

Inflammation and thrombosis. J Thromb Haemost (2003) 1.60

Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion. J Immunol (1999) 1.50

CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-{kappa}B activation. Genes Dev (2007) 1.45

Transcriptional regulation of tissue factor expression in human endothelial cells. Arterioscler Thromb Vasc Biol (1995) 1.44

The roles of proteinase-activated receptors in the vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol (2006) 1.41

Endothelium--role in regulation of coagulation and inflammation. Semin Immunopathol (2011) 1.37

Regulation of the tissue factor gene. Thromb Haemost (1997) 1.34

Thrombin and phenotypic modulation of the endothelium. Arterioscler Thromb Vasc Biol (2003) 1.31

Regulation of the tissue factor promoter in endothelial cells. Binding of NF kappa B-, AP-1-, and Sp1-like transcription factors. J Biol Chem (1995) 1.26

Inflammation, obesity, and thrombosis. Blood (2013) 1.21

Thrombin-activated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106). Blood (1998) 1.21

Mechanisms of coronary thrombosis in cigarette smoke exposure. Arterioscler Thromb Vasc Biol (2013) 1.15

Regulation of NF-κB by the CARD proteins. Immunol Rev (2012) 1.12

Thrombin regulates tissue factor and thrombomodulin mRNA levels and activities in human saphenous vein endothelial cells by distinct mechanisms. J Biol Chem (1993) 1.08

Platelet-derived S100 family member myeloid-related protein-14 regulates thrombosis. J Clin Invest (2014) 1.06

Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion are mediated by the CARMA3·Bcl10·MALT1 signalosome. J Biol Chem (2010) 1.01

CARMA3 mediates lysophosphatidic acid-stimulated cytokine secretion by bronchial epithelial cells. Am J Respir Cell Mol Biol (2008) 0.96

NF-kappaB transcription factor p50 critically regulates tissue factor in deep vein thrombosis. J Biol Chem (2008) 0.95

Thrombin and vascular inflammation. Mol Cell Biochem (2011) 0.91

Protease-activated receptor signalling by coagulation proteases in endothelial cells. Thromb Haemost (2014) 0.89

MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor. J Mol Cell Cardiol (2014) 0.84

The impact of microRNAs on the regulation of tissue factor biology. Trends Cardiovasc Med (2013) 0.82

Hypercholesterolemia and endothelial dysfunction. Curr Opin Lipidol (1995) 0.80

MicroRNA-223 inhibits tissue factor expression in vascular endothelial cells. Atherosclerosis (2014) 0.80