Published in Mol Pharm on June 24, 2016
The resurgence of platinum-based cancer chemotherapy. Nat Rev Cancer (2007) 12.38
INHIBITION OF CELL DIVISION IN ESCHERICHIA COLI BY ELECTROLYSIS PRODUCTS FROM A PLATINUM ELECTRODE. Nature (1965) 6.02
Current status of platinum-based antitumor drugs. Chem Rev (1999) 3.28
Ototoxicity in children receiving platinum chemotherapy: underestimating a commonly occurring toxicity that may influence academic and social development. J Clin Oncol (2005) 2.23
Curing metastatic testicular cancer. Proc Natl Acad Sci U S A (2002) 1.92
Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions. Am J Pathol (2010) 1.76
Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death. PLoS Genet (2008) 1.60
Endotoxemia-mediated inflammation potentiates aminoglycoside-induced ototoxicity. Sci Transl Med (2015) 1.57
Trafficking of systemic fluorescent gentamicin into the cochlea and hair cells. J Assoc Res Otolaryngol (2009) 1.48
Uptake of fluorescent gentamicin by vertebrate sensory cells in vivo. Hear Res (2006) 1.39
New cisplatin analogues in development. A review. Drugs (1993) 1.39
Intracellular localization and trafficking of fluorescein-labeled cisplatin in human ovarian carcinoma cells. Clin Cancer Res (2005) 1.30
A systemic gentamicin pathway across the stria vascularis. Hear Res (2007) 1.23
Harnessing structure-activity relationship to engineer a cisplatin nanoparticle for enhanced antitumor efficacy. Proc Natl Acad Sci U S A (2010) 1.20
Early changes in auditory function as a result of platinum chemotherapy: use of extended high-frequency audiometry and evoked distortion product otoacoustic emissions. J Clin Oncol (2007) 1.14
Aminoglycoside antibiotics impair calcium entry but not viability and motility in isolated cochlear outer hair cells. J Neurosci Res (1989) 1.05
[13N]cisplatin PET to assess pharmacokinetics of intra-arterial versus intravenous chemotherapy for malignant brain tumors. J Nucl Med (1987) 0.99
Systemic aminoglycosides are trafficked via endolymph into cochlear hair cells. Sci Rep (2011) 0.98
Radiosensitization by intratumoral administration of cisplatin in a sustained-release drug delivery system. Radiother Oncol (1999) 0.96
Tumour tropism and anti-cancer efficacy of polymer-based doxorubicin prodrugs in the treatment of subcutaneous murine B16F10 melanoma. Br J Cancer (1994) 0.93
Ototoxicity, nephrotoxicity and pharmacokinetics of cisplatin and its monohydrated complex in the guinea pig. Cancer Chemother Pharmacol (2002) 0.92
Cisplatin dose rate as a risk factor for nephrotoxicity in children. Br J Cancer (1998) 0.92
Functional mechanotransduction is required for cisplatin-induced hair cell death in the zebrafish lateral line. J Neurosci (2013) 0.92
Platinum(II)-based coordination compounds as nucleic acid labeling reagents: synthesis, reactivity, and applications in hybridization assays. Chembiochem (2003) 0.91
Pharmacokinetics of cisplatin in analbuminemic rats. Biopharm Drug Dispos (1999) 0.89
Novel separation method for highly sensitive speciation of cancerostatic platinum compounds by HPLC-ICP-MS. Anal Bioanal Chem (2004) 0.88
Effects of a single high dose of cisplatin on the melanocytes of the stria vascularis in the guinea pig. Audiol Neurootol (2007) 0.84
Identification of cisplatin-binding proteins using agarose conjugates of platinum compounds. PLoS One (2013) 0.83
Changes in pharmacokinetics of cisplatin after hepatic resection in rats. Drug Metab Dispos (1991) 0.81
Design, synthesis, and evaluation of cisplatin-containing EGFR targeting bioconjugates as potential therapeutic agents for brain tumors. Onco Targets Ther (2016) 0.77
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. Nature (2010) 18.69
Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism. Neuron (2011) 10.61
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell (2012) 6.07
Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032. J Transl Med (2010) 5.57
Dissecting the genomic complexity underlying medulloblastoma. Nature (2012) 4.77
Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res (2007) 4.48
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. Nat Immunol (2004) 4.41
Optical absorption enhancement in amorphous silicon nanowire and nanocone arrays. Nano Lett (2009) 4.35
Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia. Nature (2012) 4.01
Removal of heavy metal ions from wastewaters: a review. J Environ Manage (2010) 2.87
Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency. Cancer Res (2004) 2.79
An integrated functional genomics screening program reveals a role for BMP-9 in glucose homeostasis. Nat Biotechnol (2003) 2.53
SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development. Mol Cell (2010) 2.52
Platinum-induced ototoxicity in children: a consensus review on mechanisms, predisposition, and protection, including a new International Society of Pediatric Oncology Boston ototoxicity scale. J Clin Oncol (2012) 2.19
Detecting tissue-specific regulation of alternative splicing as a qualitative change in microarray data. Nucleic Acids Res (2004) 2.17
Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease. J Struct Biol (2005) 2.15
Towards precise classification of cancers based on robust gene functional expression profiles. BMC Bioinformatics (2005) 2.01
Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function. J Biol Chem (2008) 1.98
Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing. Nat Methods (2013) 1.88
Acceptable donor-specific antibody levels allowing for successful deceased and living donor kidney transplantation after desensitization therapy. Transplantation (2008) 1.84
Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX. Structure (2009) 1.79
Redox-sensitive transcriptional control by a thiol/disulphide switch in the global regulator, Spx. Mol Microbiol (2005) 1.79
Hypoxia accelerates nitric oxide-dependent inhibition of mitochondrial complex I in activated macrophages. Am J Physiol Regul Integr Comp Physiol (2004) 1.74
Lysosomal transmembrane protein LAPTM4B promotes autophagy and tolerance to metabolic stress in cancer cells. Cancer Res (2011) 1.73
Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases. Sci Signal (2013) 1.73
Selective expression of the Cre recombinase in late-stage thymocytes using the distal promoter of the Lck gene. J Immunol (2005) 1.68
Reconstruction of circulation in the fingertip without vein repair in zone I replantation. J Hand Surg Am (2008) 1.56
Risk factors associated with fluoroquinolone-resistant tuberculosis in a Beijing tuberculosis referral hospital. Respirology (2011) 1.50
Genetic background of catecholaminergic polymorphic ventricular tachycardia in Japan. Circ J (2013) 1.50
Functional hair cell mechanotransducer channels are required for aminoglycoside ototoxicity. PLoS One (2011) 1.50
Trafficking of systemic fluorescent gentamicin into the cochlea and hair cells. J Assoc Res Otolaryngol (2009) 1.48
N-halosuccinimide/BF3-H2O, efficient electrophilic halogenating systems for aromatics. J Am Chem Soc (2004) 1.47
Cinnabar is not converted into methylmercury by human intestinal bacteria. J Ethnopharmacol (2011) 1.45
Potential for serious environmental threats from uncontrolled co-processing of wastes in cement kilns. Environ Sci Technol (2012) 1.44
[Research on differential genes related with qi stagnation constitution]. Zhongguo Zhong Xi Yi Jie He Za Zhi (2011) 1.44
L-type calcium channel mutations in Japanese patients with inherited arrhythmias. Circ J (2013) 1.44
Associations between interleukin-6 gene -174 C/G and -572 C/G polymorphisms and the risk of gastric cancer: a meta-analysis. J Surg Oncol (2012) 1.44
Bioinformatics analysis of alternative splicing. Brief Bioinform (2005) 1.44
High copper selectively alters lipid metabolism and cell cycle machinery in the mouse model of Wilson disease. J Biol Chem (2007) 1.43
Characteristics and treatment outcomes of patients with MDR and XDR tuberculosis in a TB referral hospital in Beijing: a 13-year experience. PLoS One (2011) 1.42
2-Chloro-N-isopropyl-N-phenyl-acetamide. Acta Crystallogr Sect E Struct Rep Online (2010) 1.39
One-stage surgical management for children with spinal tuberculosis by anterior decompression and posterior instrumentation. Int Orthop (2009) 1.39
The N-terminal metal-binding site 2 of the Wilson's Disease Protein plays a key role in the transfer of copper from Atox1. J Biol Chem (2004) 1.38
Effect of a Novel Stent on Re-Endothelialization, Platelet Adhesion, and Neointimal Formation. J Atheroscler Thromb (2015) 1.38
A wireless electronic nose system using a Fe2O3 gas sensing array and least squares support vector regression. Sensors (Basel) (2011) 1.37
Cytoplasmic and intra-nuclear binding of gentamicin does not require endocytosis. Hear Res (2005) 1.37
Identifying gene regulatory networks in schizophrenia. Neuroimage (2010) 1.34
The p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis. Genes Dev (2012) 1.32
Rapid positive selection of stable integrants following transfection of Plasmodium falciparum. Mol Biochem Parasitol (2002) 1.29
No clinical benefit of gender-specific total knee arthroplasty. Acta Orthop (2014) 1.25
The genome of the plant growth-promoting rhizobacterium Paenibacillus polymyxa M-1 contains nine sites dedicated to nonribosomal synthesis of lipopeptides and polyketides. J Bacteriol (2011) 1.25
Overexpression of Id-1 in prostate cancer cells promotes angiogenesis through the activation of vascular endothelial growth factor (VEGF). Carcinogenesis (2005) 1.24
Renal clearance of gamma-hydroxybutyric acid in rats: increasing renal elimination as a detoxification strategy. J Pharmacol Exp Ther (2005) 1.24
A systemic gentamicin pathway across the stria vascularis. Hear Res (2007) 1.23
[Prevalence and etiology of people with hearing impairment in China]. Zhonghua Liu Xing Bing Xue Za Zhi (2008) 1.22
TRPV1 regulators mediate gentamicin penetration of cultured kidney cells. Hear Res (2005) 1.21
Motion aftereffects transfer between touch and vision. Curr Biol (2009) 1.21
Traditional Chinese medicine herbal preparations in restless legs syndrome (RLS) treatment: a review and probable first description of RLS in 1529. Sleep Med Rev (2012) 1.20
Structure of the S1S2 glutamate binding domain of GLuR3. Proteins (2009) 1.20
The complete genome of Bacillus amyloliquefaciens subsp. plantarum CAU B946 contains a gene cluster for nonribosomal synthesis of iturin A. J Bacteriol (2012) 1.20
Molecular simulation of protein adsorption and desorption on hydroxyapatite surfaces. Biomaterials (2007) 1.20
Supported employment outcomes of a randomized controlled trial of ACT and clubhouse models. Psychiatr Serv (2006) 1.19
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities. Nat Med (2013) 1.19
Design for hydrogen storage materials via observation of adsorption sites by computer tomography. J Phys Chem B (2007) 1.19
ASD: a comprehensive database of allosteric proteins and modulators. Nucleic Acids Res (2010) 1.18
Inactivation of human MAD2B in nasopharyngeal carcinoma cells leads to chemosensitization to DNA-damaging agents. Cancer Res (2006) 1.17
Probing the role of axial methionine in the blue copper center of azurin with unnatural amino acids. J Am Chem Soc (2003) 1.15
Expression of Sox2 and Oct4 and their clinical significance in human non-small-cell lung cancer. Int J Mol Sci (2012) 1.15
Anti-angiotensin type 1 receptor antibodies associated with antibody mediated rejection in donor HLA antibody negative patients. Transplantation (2010) 1.15
RNA helicase A interacts with dsDNA and topoisomerase IIalpha. Nucleic Acids Res (2003) 1.14
Expression of HIWI in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis. BMC Cancer (2009) 1.13
Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia. Proc Natl Acad Sci U S A (2013) 1.13
Crenolanib is a selective type I pan-FLT3 inhibitor. Proc Natl Acad Sci U S A (2014) 1.12
TRPV4 enhances the cellular uptake of aminoglycoside antibiotics. J Cell Sci (2008) 1.11
Diversity dynamics of silurian-early carboniferous land plants in South china. PLoS One (2013) 1.11
The basic leucine zipper transcription factor Moatf1 mediates oxidative stress responses and is necessary for full virulence of the rice blast fungus Magnaporthe oryzae. Mol Plant Microbe Interact (2010) 1.11
R-SNARE homolog MoSec22 is required for conidiogenesis, cell wall integrity, and pathogenesis of Magnaporthe oryzae. PLoS One (2010) 1.10
Effete-mediated degradation of Cyclin A is essential for the maintenance of germline stem cells in Drosophila. Development (2009) 1.10
Phenotype variability in patients carrying KCNJ2 mutations. Circ Cardiovasc Genet (2012) 1.09
Pediatric pedicle screws: comparative effectiveness and safety: a systematic literature review from the Scoliosis Research Society and the Pediatric Orthopaedic Society of North America task force. J Bone Joint Surg Am (2011) 1.09
A common property of amyotrophic lateral sclerosis-associated variants: destabilization of the copper/zinc superoxide dismutase electrostatic loop. J Biol Chem (2009) 1.08
An early nodulin-like protein accumulates in the sieve element plasma membrane of Arabidopsis. Plant Physiol (2007) 1.08
Vanilloid receptors in hearing: altered cochlear sensitivity by vanilloids and expression of TRPV1 in the organ of corti. J Neurophysiol (2003) 1.07
Further characterization of human DNA polymerase delta interacting protein 38. J Biol Chem (2005) 1.07
Size-controllable synthesis of monodispersed SnO2 nanoparticles and application in electrocatalysts. J Phys Chem B (2005) 1.06
9p21 is a shared susceptibility locus strongly for coronary artery disease and weakly for ischemic stroke in Chinese Han population. Circ Cardiovasc Genet (2009) 1.06
Microencapsulation of bacteriophage felix O1 into chitosan-alginate microspheres for oral delivery. Appl Environ Microbiol (2008) 1.05
Job satisfaction and its modeling among township health center employees: a quantitative study in poor rural China. BMC Health Serv Res (2010) 1.05
Acoustic trauma increases cochlear and hair cell uptake of gentamicin. PLoS One (2011) 1.05
Knockdown of cyclin D1 inhibits proliferation, induces apoptosis, and attenuates the invasive capacity of human glioblastoma cells. J Neurooncol (2011) 1.05
An outbreak of a nosocomial NDM-1-producing Klebsiella pneumoniae ST147 at a teaching hospital in mainland China. Microb Drug Resist (2013) 1.05
The N2pc component in ERP and the lateralization effect of language on color perception. Neurosci Lett (2009) 1.05
Polo-like kinases and centrosome regulation. Oncogene (2002) 1.04
Anti-apoptotic role of TWIST and its association with Akt pathway in mediating taxol resistance in nasopharyngeal carcinoma cells. Int J Cancer (2007) 1.04
Association of common variants of CYP4A11 and CYP4F2 with stroke in the Han Chinese population. Pharmacogenet Genomics (2010) 1.04
Induced stepwise conformational change of human serum albumin on carbon nanotube surfaces. Biomaterials (2008) 1.03
Hormonal and dietary modulation of mammary carcinogenesis in mouse mammary tumor virus-c-erbB-2 transgenic mice. Cancer Res (2003) 1.03