The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels.

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Published in Nat Commun on June 22, 2016

Authors

Navid Bavi1,2, D Marien Cortes3, Charles D Cox1,2, Paul R Rohde1, Weihong Liu4, Joachim W Deitmer5, Omid Bavi1,6, Pavel Strop7, Adam P Hill1,2, Douglas Rees7, Ben Corry8, Eduardo Perozo3, Boris Martinac9,10

Author Affiliations

1: Division of Molecular Cardiology and Biophysics, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales 2010, Australia.
2: St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Darlinghurst, New South Wales 2010, Australia.
3: Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, Illinois 60637, USA.
4: Department of Pharmacology, University of Western Australia, Nedlands, Western Australia 6009, Australia.
5: FB Biologie, University of Kaiserslautern, Kaiserslautern D-67663, Germany.
6: Institute for Nanoscience and Nanotechnology, Sharif University of Technology, Tehran 1458889694, Iran.
7: Division of Chemistry and Chemical Engineering, Howard Hughes Medical Institute, California Institute of Technology, Pasadena, California 91125, USA.
8: Research School of Biology, The Australian National University, Acton, Australian Capital Territory 2601, Australia.
9: Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales 2010, Australia.
10: St Vincent's Clinical School, University of New South Wales, Darlinghurst, New South Wales 2010, Australia.

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