Published in Sci Rep on July 07, 2016
Graphical Modeling Meets Systems Pharmacology. Gene Regul Syst Bio (2017) 0.75
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A (2005) 167.46
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol (2004) 101.91
Circos: an information aesthetic for comparative genomics. Genome Res (2009) 40.02
Hierarchical organization of modularity in metabolic networks. Science (2002) 22.47
BioGRID: a general repository for interaction datasets. Nucleic Acids Res (2006) 22.41
Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics (2002) 20.59
WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics (2008) 18.58
Systems biology: a brief overview. Science (2002) 14.69
Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol (2006) 11.36
Proteomics. Tissue-based map of the human proteome. Science (2015) 10.21
Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci U S A (2007) 9.71
ToppGene Suite for gene list enrichment analysis and candidate gene prioritization. Nucleic Acids Res (2009) 7.34
A systems biology approach for pathway level analysis. Genome Res (2007) 6.95
Ten years of pathway analysis: current approaches and outstanding challenges. PLoS Comput Biol (2012) 6.38
Whole-genome cartography of estrogen receptor alpha binding sites. PLoS Genet (2007) 5.85
A novel signaling pathway impact analysis. Bioinformatics (2008) 5.06
Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool. BMC Bioinformatics (2013) 4.73
Forming functional fat: a growing understanding of adipocyte differentiation. Nat Rev Mol Cell Biol (2011) 4.72
Executable cell biology. Nat Biotechnol (2007) 4.64
g:Profiler--a web server for functional interpretation of gene lists (2011 update). Nucleic Acids Res (2011) 3.94
Empirical array quality weights in the analysis of microarray data. BMC Bioinformatics (2006) 3.54
A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data. Nucleic Acids Res (2009) 3.50
Inferring pathway activity toward precise disease classification. PLoS Comput Biol (2008) 3.48
Interplay between lipids and branched-chain amino acids in development of insulin resistance. Cell Metab (2012) 3.26
GATHER: a systems approach to interpreting genomic signatures. Bioinformatics (2006) 3.22
The ConsensusPathDB interaction database: 2013 update. Nucleic Acids Res (2012) 2.94
Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation. Int J Obes Relat Metab Disord (2001) 2.94
The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences. Clin Chem (2008) 2.72
Methods of integrating data to uncover genotype-phenotype interactions. Nat Rev Genet (2015) 2.66
Life, logic and information. Nature (2008) 2.51
Adipogenesis: from stem cell to adipocyte. Annu Rev Biochem (2012) 2.46
Regulation of PPARgamma activity during adipogenesis. Int J Obes (Lond) (2005) 2.31
DAVID-WS: a stateful web service to facilitate gene/protein list analysis. Bioinformatics (2012) 2.14
EnrichNet: network-based gene set enrichment analysis. Bioinformatics (2012) 1.92
Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels. J Biol Chem (2010) 1.80
Transcriptional factors that promote formation of white adipose tissue. Mol Cell Endocrinol (2009) 1.74
Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes. J Biol Chem (2006) 1.70
The digital code of DNA. Nature (2003) 1.70
JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas. Cancer Cell (2007) 1.56
Human SGBS cells - a unique tool for studies of human fat cell biology. Obes Facts (2008) 1.55
Regulation of proteasome activity in health and disease. Biochim Biophys Acta (2013) 1.52
Changes in integrin expression during adipocyte differentiation. Cell Metab (2005) 1.51
Methods and approaches in the topology-based analysis of biological pathways. Front Physiol (2013) 1.48
The cell biology of fat expansion. J Cell Biol (2015) 1.37
Adipogenesis and fat-cell function in obesity and diabetes. Trends Mol Med (2002) 1.33
Using networks to measure similarity between genes: association index selection. Nat Methods (2013) 1.30
Adipocyte and adipogenesis. Eur J Cell Biol (2013) 1.27
Unifying immunology with informatics and multiscale biology. Nat Immunol (2014) 1.15
Metabolic phenotyping of a model of adipocyte differentiation. Physiol Genomics (2009) 1.10
RDAVIDWebService: a versatile R interface to DAVID. Bioinformatics (2013) 1.10
Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade. Stem Cell Res Ther (2013) 1.04
State of the APC/C: organization, function, and structure. Crit Rev Biochem Mol Biol (2011) 1.02
The tumor suppressors pRB and p53 as regulators of adipocyte differentiation and function. Expert Opin Ther Targets (2009) 1.02
Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis. Nat Chem Biol (2015) 0.99
Interaction between p53 and estradiol pathways in transcriptional responses to chemotherapeutics. Cell Cycle (2013) 0.98
De novo lipogenesis in the differentiating human adipocyte can provide all fatty acids necessary for maturation. J Lipid Res (2011) 0.97
Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism. Am J Physiol Endocrinol Metab (2015) 0.96
FOXM1: an emerging master regulator of DNA damage response and genotoxic agent resistance. Biochim Biophys Acta (2014) 0.95
The fat controller: adipocyte development. PLoS Biol (2012) 0.94
Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis. J Biol Chem (2014) 0.93
Gene Set/Pathway enrichment analysis. Methods Mol Biol (2013) 0.92
Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis. PLoS One (2010) 0.91
Regulation of adipose differentiation by fructose and GluT5. Mol Endocrinol (2012) 0.91
Cytoskeletal disassembly and cell rounding promotes adipogenesis from ES cells. Stem Cell Rev (2010) 0.91
JEPETTO: a Cytoscape plugin for gene set enrichment and topological analysis based on interaction networks. Bioinformatics (2013) 0.90
A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation. Genome Res (2015) 0.90
Chemokine network during adipogenesis in 3T3-L1 cells: Differential response between growth and proinflammatory factor in preadipocytes vs. adipocytes. Adipocyte (2014) 0.90
Adipocytes under assault: environmental disruption of adipose physiology. Biochim Biophys Acta (2013) 0.89
Cytoscape tools for the web age: D3.js and Cytoscape.js exporters. F1000Res (2014) 0.89
Inhibition of Notch Signaling Promotes the Adipogenic Differentiation of Mesenchymal Stem Cells Through Autophagy Activation and PTEN-PI3K/AKT/mTOR Pathway. Cell Physiol Biochem (2015) 0.88
A mutation in the c-fos gene associated with congenital generalized lipodystrophy. Orphanet J Rare Dis (2013) 0.86
Efficacy of autologous serum in human adipose-derived stem cells; cell markers, growth factors and differentiation. Cell Mol Biol (Noisy-le-grand) (2011) 0.84
The elusive endogenous adipogenic PPARγ agonists: Lining up the suspects. Prog Lipid Res (2015) 0.83
White adipose tissue reference network: a knowledge resource for exploring health-relevant relations. Genes Nutr (2014) 0.83
Fat depot-specific gene signature and ECM remodeling of Sca1(high) adipose-derived stem cells. Matrix Biol (2014) 0.83
Fra-2/AP-1 controls adipocyte differentiation and survival by regulating PPARγ and hypoxia. Cell Death Differ (2014) 0.82
Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice. J Nutr Biochem (2012) 0.82
IGF1 Promotes Adipogenesis by a Lineage Bias of Endogenous Adipose Stem/Progenitor Cells. Stem Cells (2015) 0.81
Cooperative interactions between p53 and NFκB enhance cell plasticity. Oncotarget (2014) 0.81
Metabolic fate of fructose in human adipocytes: a targeted (13)C tracer fate association study. Metabolomics (2014) 0.81
PPARγ and Wnt Signaling in Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells. Curr Stem Cell Res Ther (2016) 0.80
Very long-chain-fatty acids enhance adipogenesis through coregulation of Elovl3 and PPARγ in 3T3-L1 cells. Am J Physiol Endocrinol Metab (2012) 0.80
Using gene expression to predict the secretome of differentiating human preadipocytes. Int J Obes (Lond) (2009) 0.80
The SGBS cell strain as a model for the in vitro study of obesity and cancer. Clin Transl Oncol (2012) 0.79
Differential regulation enrichment analysis via the integration of transcriptional regulatory network and gene expression data. Bioinformatics (2014) 0.79
Laminin production and basement membrane deposition by mesenchymal stem cells upon adipogenic differentiation. J Histochem Cytochem (2013) 0.79
Novel role of androgens in mitochondrial fission and apoptosis. Mol Cancer Res (2011) 0.78
Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis. Arch Biochem Biophys (2015) 0.78
Transforming growth factor-β superfamily, implications in development and differentiation of stem cells. Biomol Concepts (2012) 0.78
Arp2/3 complex regulates adipogenesis by controlling cortical actin remodelling. Biochem J (2014) 0.78
Syndecan-1 regulates adipogenesis: new insights in dedifferentiated liposarcoma tumorigenesis. Carcinogenesis (2014) 0.78
Prolactin (PRL) in adipose tissue: regulation and functions. Adv Exp Med Biol (2015) 0.77
Bioconductor's EnrichmentBrowser: seamless navigation through combined results of set- & network-based enrichment analysis. BMC Bioinformatics (2016) 0.77
Dynamics of mRNA and polysomal abundance in early 3T3-L1 adipogenesis. BMC Genomics (2014) 0.77
Lightening up a notch: Notch regulation of energy metabolism. Nat Med (2014) 0.77
Role of signaling pathways in mesenchymal stem cell differentiation. Curr Stem Cell Res Ther (2014) 0.77
Faspad: fast signaling pathway detection. Bioinformatics (2007) 0.76
Fructose Alters Intermediary Metabolism of Glucose in Human Adipocytes and Diverts Glucose to Serine Oxidation in the One-Carbon Cycle Energy Producing Pathway. Metabolites (2015) 0.76
Effects of leucine supplementation and serum withdrawal on branched-chain amino acid pathway gene and protein expression in mouse adipocytes. PLoS One (2014) 0.76
Rank-based miRNA signatures for early cancer detection. Biomed Res Int (2014) 0.82