Published in J Biol Chem on July 08, 2016
Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing. Biophys J (1999) 13.18
Translocation of proteins into mitochondria. Annu Rev Biochem (2007) 7.53
Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine. Cell (2000) 7.25
The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions. EMBO J (1998) 5.61
Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex. Nature (2006) 5.42
Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70. Cell (2003) 4.46
Differential interactions of p23 and the TPR-containing proteins Hop, Cyp40, FKBP52 and FKBP51 with Hsp90 mutants. Cell Stress Chaperones (1998) 1.91
Structure, function and regulation of the hsp90 machinery. Biomed J (2013) 1.81
Import of ADP/ATP carrier into mitochondria: two receptors act in parallel. J Cell Biol (1990) 1.72
Asymmetric activation of the hsp90 dimer by its cochaperone aha1. Mol Cell (2010) 1.65
Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis. Mol Biol Cell (2010) 1.41
The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop. EMBO J (2012) 1.36
Hsp90: structure and function. Top Curr Chem (2013) 1.27
Low-affinity binding determined by titration calorimetry using a high-affinity coupling ligand: a thermodynamic study of ligand binding to protein tyrosine phosphatase 1B. Anal Biochem (1998) 1.21
Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography. J Struct Biol (2006) 1.21
Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import. Mol Biol Cell (2007) 1.20
The role of Hsp90 in protein complex assembly. Biochim Biophys Acta (2011) 1.19
Cross-link guided molecular modeling with ROSETTA. PLoS One (2013) 1.18
Partial unfolding of diverse SH3 domains on a wide timescale. J Mol Biol (2006) 1.17
Analysis of protein complexes with hydrogen exchange and mass spectrometry. Analyst (2003) 1.12
Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading. J Biol Chem (2009) 1.07
Hsp90: breaking the symmetry. Mol Cell (2015) 1.04
Chaperone ligand-discrimination by the TPR-domain protein Tah1. Biochem J (2008) 0.98
The network interaction of the human cytosolic 90 kDa heat shock protein Hsp90: A target for cancer therapeutics. J Proteomics (2012) 0.98
Using hydrogen/deuterium exchange mass spectrometry to study conformational changes in granulocyte colony stimulating factor upon PEGylation. J Am Soc Mass Spectrom (2012) 0.87
Function of cytosolic chaperones in Tom70-mediated mitochondrial import. Protein Pept Lett (2011) 0.86
Interaction between the human mitochondrial import receptors Tom20 and Tom70 in vitro suggests a chaperone displacement mechanism. J Biol Chem (2011) 0.84
SIM-XL: A powerful and user-friendly tool for peptide cross-linking analysis. J Proteomics (2015) 0.82
The effect of celastrol, a triterpene with antitumorigenic activity, on conformational and functional aspects of the human 90kDa heat shock protein Hsp90α, a chaperone implicated in the stabilization of the tumor phenotype. Biochim Biophys Acta (2014) 0.82
Differences in conformational dynamics within the Hsp90 chaperone family reveal mechanistic insights. Front Mol Biosci (2014) 0.81
The structural plasticity of Tom71 for mitochondrial precursor translocations. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.80
Human mitochondrial import receptor Tom70 functions as a monomer. Biochem J (2010) 0.79
Stoichiometry and thermodynamics of the interaction between the C-terminus of human 90kDa heat shock protein Hsp90 and the mitochondrial translocase of outer membrane Tom70. Arch Biochem Biophys (2011) 0.78
A presequence-binding groove in Tom70 supports import of Mdl1 into mitochondria. Biochim Biophys Acta (2015) 0.78
Structural and functional characterization of the chaperone Hsp70 from sugarcane. Insights into conformational changes during cycling from cross-linking/mass spectrometry assays. J Proteomics (2014) 0.77
Conformational and functional studies of a cytosolic 90 kDa heat shock protein Hsp90 from sugarcane. Plant Physiol Biochem (2013) 0.77