Published in Zhonghua Xue Ye Xue Za Zhi on June 14, 2016
Whole-genome shotgun assembly and analysis of the genome of Fugu rubripes. Science (2002) 20.59
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature (2000) 13.45
p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature (1999) 13.21
Smoking in China: findings of the 1996 National Prevalence Survey. JAMA (1999) 8.67
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science (2000) 8.56
Recognition of unique carboxyl-terminal motifs by distinct PDZ domains. Science (1997) 8.16
Receptor specificity of the fibroblast growth factor family. J Biol Chem (1996) 7.58
Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell (1994) 6.45
The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity (1999) 6.10
Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism. Science (1997) 5.40
Air pollution and mortality in Philadelphia, 1974-1988. Am J Epidemiol (1997) 5.35
Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search. Science (1996) 5.06
Physical characterization of the herpes simplex virus latency-associated transcript in neurons. J Virol (1988) 4.85
A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations. Nat Biotechnol (2001) 4.66
The Human Connectome Project: a data acquisition perspective. Neuroimage (2012) 4.64
Activation of PPARgamma coactivator-1 through transcription factor docking. Science (1999) 4.33
Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding. Mol Cell (1999) 4.02
Visual acuity and quality of life in patients with cataract in Doumen County, China. Ophthalmology (1999) 3.82
Synaptic mechanisms and network dynamics underlying spatial working memory in a cortical network model. Cereb Cortex (2000) 3.80
Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. Nat Genet (2002) 3.67
Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003. Lancet (2003) 3.66
Regulation of cellular interferon production: enhancement by antimetabolites. Proc Natl Acad Sci U S A (1970) 3.66
A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem. Proc Natl Acad Sci U S A (1999) 3.63
AUX/IAA proteins are active repressors, and their stability and activity are modulated by auxin. Plant Cell (2001) 3.42
Theta oscillations in somata and dendrites of hippocampal pyramidal cells in vivo: activity-dependent phase-precession of action potentials. Hippocampus (1998) 3.23
The herpes simplex virus latency-associated transcript is spliced during the latent phase of infection. J Virol (1988) 3.22
Effects of neuromodulation in a cortical network model of object working memory dominated by recurrent inhibition. J Comput Neurosci (2001) 3.16
Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand. Nature (1995) 3.07
The SPOROCYTELESS gene of Arabidopsis is required for initiation of sporogenesis and encodes a novel nuclear protein. Genes Dev (1999) 3.07
Deregulated expression of c-Myc depletes epidermal stem cells. Nat Genet (2001) 3.00
Genetic susceptibility to asthma--bronchial hyperresponsiveness coinherited with a major gene for atopy. N Engl J Med (1995) 2.98
Cerebral metabolic suppression during hypothermic circulatory arrest in humans. Ann Thorac Surg (1999) 2.90
Functional neuronavigation combined with intra-operative 3D ultrasound: initial experiences during surgical resections close to eloquent brain areas and future directions in automatic brain shift compensation of preoperative data. Acta Neurochir (Wien) (2007) 2.89
Formation of native hepatitis C virus glycoprotein complexes. J Virol (1997) 2.87
Human cytomegalovirus latent gene expression in granulocyte-macrophage progenitors in culture and in seropositive individuals. Proc Natl Acad Sci U S A (1996) 2.87
Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia. Nat Genet (1996) 2.87
Localization of the G protein betagamma complex in living cells during chemotaxis. Science (2000) 2.87
High interlaboratory reproducibility of DNA sequence-based typing of bacteria in a multicenter study. J Clin Microbiol (2006) 2.80
Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation. J Cell Biol (1997) 2.78
Characteristics of prostate cancer in families potentially linked to the hereditary prostate cancer 1 (HPC1) locus. JAMA (1997) 2.73
Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity. Virology (1996) 2.71
Interaction between ATM protein and c-Abl in response to DNA damage. Nature (1997) 2.70
Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics. J Virol (1994) 2.64
Structural analysis of a set of proteins resulting from a bacterial genomics project. Proteins (2005) 2.59
The linkage of genes for the human interferon-induced antiviral protein and indophenol oxidase-B traits to chromosome G-21. J Exp Med (1973) 2.57
Correlation of the highest-energy cosmic rays with nearby extragalactic objects. Science (2007) 2.57
Extracellular histones increase plasma thrombin generation by impairing thrombomodulin-dependent protein C activation. J Thromb Haemost (2011) 2.51
Intensive care unit telemedicine: alternate paradigm for providing continuous intensivist care. Crit Care Med (2000) 2.50
Activation and association of Stat3 with Src in v-Src-transformed cell lines. Mol Cell Biol (1996) 2.47
Phosphorylation of the hepatitis C virus NS5A protein in vitro and in vivo: properties of the NS5A-associated kinase. J Virol (1997) 2.39
Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis. Science (1996) 2.36
Molecular diagnosis of infective endocarditis--a new Duke's criterion. Scand J Infect Dis (2001) 2.36
Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia. Clin Cancer Res (2001) 2.35
Pioneer factors, genetic competence, and inductive signaling: programming liver and pancreas progenitors from the endoderm. Cold Spring Harb Symp Quant Biol (2008) 2.34
Disability in optic neuritis correlates with diffusion tensor-derived directional diffusivities. Neurology (2008) 2.33
JNK is required for effector T-cell function but not for T-cell activation. Nature (2000) 2.33
A role for NMDA-receptor channels in working memory. Nat Neurosci (1998) 2.28
Birth weight and subsequent risk of obesity: a systematic review and meta-analysis. Obes Rev (2011) 2.22
Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity. Proc Natl Acad Sci U S A (1997) 2.21
CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response. J Exp Med (1996) 2.21
Acupuncture for pain relief during induced labour in nulliparae: a randomised controlled study. BJOG (2011) 2.19
Nodeless superconducting gap in A(x)Fe2Se2 (A=K,Cs) revealed by angle-resolved photoemission spectroscopy. Nat Mater (2011) 2.16
A survey of blindness and cataract surgery in Doumen County, China. Ophthalmology (1999) 2.15
A genetic linkage map of the bovine genome. Nat Genet (1994) 2.15
Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect. Am J Hum Genet (1995) 2.09
17beta-estradiol enhances NMDA receptor-mediated EPSPs and long-term potentiation. J Neurophysiol (1999) 2.08
New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo. J Biol Chem (2000) 2.07
Completely diverted tube ileostomy compared with loop ileostomy for protection of low colorectal anastomosis: a pilot study. Colorectal Dis (2014) 2.06
The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues. Nat Genet (1995) 2.02
Primary care, infant mortality, and low birth weight in the states of the USA. J Epidemiol Community Health (2004) 2.01
Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis. Proc Natl Acad Sci U S A (2001) 2.00
Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions. J Steroid Biochem Mol Biol (1999) 2.00
Gene expression of osteoprotegerin ligand, osteoprotegerin, and receptor activator of NF-kappaB in giant cell tumor of bone: possible involvement in tumor cell-induced osteoclast-like cell formation. Am J Pathol (2000) 1.99
Retinal nerve fibre layer thickness measurement reproducibility improved with spectral domain optical coherence tomography. Br J Ophthalmol (2009) 1.97
Weighing the care: physicians' reactions to the size of a patient. Int J Obes Relat Metab Disord (2001) 1.96
Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state. Science (1974) 1.95
4-Anilino-6,7-dialkoxyquinoline-3-carbonitrile inhibitors of epidermal growth factor receptor kinase and their bioisosteric relationship to the 4-anilino-6,7-dialkoxyquinazoline inhibitors. J Med Chem (2000) 1.94
Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am J Hum Genet (2000) 1.94
Low-temperature in situ large strain plasticity of ceramic SiC nanowires and its atomic-scale mechanism. Nano Lett (2007) 1.91
BRCA1 maps proximal to D17S579 on chromosome 17q21 by genetic analysis. Am J Hum Genet (1993) 1.90
Down-regulation of p63 is required for epidermal UV-B-induced apoptosis. Cancer Res (2000) 1.88
Identification of Arabidopsis histone deacetylase HDA6 mutants that affect transgene expression. Plant Cell (2001) 1.87
Neutron-diffraction measurements of magnetic order and a structural transition in the parent BaFe2As2 compound of FeAs-based high-temperature superconductors. Phys Rev Lett (2008) 1.86
P504S: a new molecular marker for the detection of prostate carcinoma. Am J Surg Pathol (2001) 1.86
Pollination: flexible style that encourages outcrossing. Nature (2001) 1.85
The impact of ethnicity and sex on subclinical cardiovascular disease: the Diabetes Heart Study. Diabetologia (2005) 1.84
Dynamic changes in Rad51 distribution on chromatin during meiosis in male and female vertebrates. Chromosoma (1995) 1.83
Evidence for a locus regulating total serum IgE levels mapping to chromosome 5. Genomics (1994) 1.81
An essential heparin-binding domain in the fibroblast growth factor receptor kinase. Science (1993) 1.81
Coexistence of static magnetism and superconductivity in SmFeAsO(1-x)F(x) as revealed by muon spin rotation. Nat Mater (2009) 1.79
Effect of low- and high-frequency TENS on Met-enkephalin-Arg-Phe and dynorphin A immunoreactivity in human lumbar CSF. Pain (1991) 1.79
Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone. EMBO J (1999) 1.78
Effect of sodium chloride on transport of bacteria in a saturated aquifer material. Appl Environ Microbiol (1991) 1.78
First evidence of pep solar neutrinos by direct detection in Borexino. Phys Rev Lett (2012) 1.77
Diffusing wave spectroscopy microrheology of actin filament networks. Biophys J (1999) 1.77
Pan1p, End3p, and S1a1p, three yeast proteins required for normal cortical actin cytoskeleton organization, associate with each other and play essential roles in cell wall morphogenesis. Mol Cell Biol (2000) 1.76
Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells. J Biol Chem (1999) 1.75
Phonon density of states of iron up to 153 gigapascals. Science (2001) 1.74
Detection of incidental colorectal tumours with 18F-labelled 2-fluoro-2-deoxyglucose positron emission tomography/computed tomography scans: results of a prospective study. Colorectal Dis (2011) 1.73