Published in Big Data on June 01, 2016
KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res (2000) 117.00
Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences. Genome Biol (2010) 39.63
Galaxy: a platform for interactive large-scale genome analysis. Genome Res (2005) 35.75
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov (2012) 26.98
Galaxy: a web-based genome analysis tool for experimentalists. Curr Protoc Mol Biol (2010) 17.00
NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res (2012) 15.84
limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res (2015) 14.81
Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2). J Am Med Inform Assoc (2010) 10.51
The Reactome pathway knowledgebase. Nucleic Acids Res (2013) 8.56
The Systems Biology Graphical Notation. Nat Biotechnol (2009) 8.53
Extending KNIME for next-generation sequencing data analysis. Bioinformatics (2011) 8.45
Mechanisms underlying inflammation in neurodegeneration. Cell (2010) 7.66
caGrid 1.0: an enterprise Grid infrastructure for biomedical research. J Am Med Inform Assoc (2007) 6.15
A comprehensive pathway map of epidermal growth factor receptor signaling. Mol Syst Biol (2005) 5.68
Mobyle: a new full web bioinformatics framework. Bioinformatics (2009) 4.96
STRIDE--An integrated standards-based translational research informatics platform. AMIA Annu Symp Proc (2009) 4.43
The Taverna workflow suite: designing and executing workflows of Web Services on the desktop, web or in the cloud. Nucleic Acids Res (2013) 4.32
Causal analysis approaches in Ingenuity Pathway Analysis. Bioinformatics (2013) 4.30
Instrumenting the health care enterprise for discovery research in the genomic era. Genome Res (2009) 4.13
Snakemake--a scalable bioinformatics workflow engine. Bioinformatics (2012) 3.80
A genomic pathway approach to a complex disease: axon guidance and Parkinson disease. PLoS Genet (2007) 3.28
Translational bioinformatics: coming of age. J Am Med Inform Assoc (2008) 2.81
The $1,000 genome, the $100,000 analysis? Genome Med (2010) 2.79
iDASH: integrating data for analysis, anonymization, and sharing. J Am Med Inform Assoc (2011) 2.51
Chipster: user-friendly analysis software for microarray and other high-throughput data. BMC Genomics (2011) 2.31
Harnessing cloud computing with Galaxy Cloud. Nat Biotechnol (2011) 2.19
Systems cancer medicine: towards realization of predictive, preventive, personalized and participatory (P4) medicine. J Intern Med (2012) 2.13
Dalliance: interactive genome viewing on the web. Bioinformatics (2011) 2.07
Yabi: An online research environment for grid, high performance and cloud computing. Source Code Biol Med (2012) 1.74
An i2b2-based, generalizable, open source, self-scaling chronic disease registry. J Am Med Inform Assoc (2012) 1.39
WikiPathways: capturing the full diversity of pathway knowledge. Nucleic Acids Res (2015) 1.35
Integrating pathways of Parkinson's disease in a molecular interaction map. Mol Neurobiol (2013) 1.34
Scientific workflow systems: Pipeline Pilot and KNIME. J Comput Aided Mol Des (2012) 1.32
Big data in biomedicine. Drug Discov Today (2013) 1.23
Using the i2b2 hive for clinical discovery: an example. AMIA Annu Symp Proc (2007) 1.22
Tavaxy: integrating Taverna and Galaxy workflows with cloud computing support. BMC Bioinformatics (2012) 1.21
A survey on annotation tools for the biomedical literature. Brief Bioinform (2012) 1.19
Innovative information visualization of electronic health record data: a systematic review. J Am Med Inform Assoc (2014) 1.18
Translational research platforms integrating clinical and omics data: a review of publicly available solutions. Brief Bioinform (2014) 1.17
TRIAD: The Translational Research Informatics and Data Management Grid. Appl Clin Inform (2011) 1.14
AlzPathway: a comprehensive map of signaling pathways of Alzheimer's disease. BMC Syst Biol (2012) 1.13
Genomic cloud computing: legal and ethical points to consider. Eur J Hum Genet (2014) 1.12
Managing, analysing, and integrating big data in medical bioinformatics: open problems and future perspectives. Biomed Res Int (2014) 1.08
Impaired long distance functional connectivity and weighted network architecture in Alzheimer's disease. Cereb Cortex (2013) 1.07
From big data analysis to personalized medicine for all: challenges and opportunities. BMC Med Genomics (2015) 1.04
Big data for health. IEEE J Biomed Health Inform (2015) 1.03
A review of bioinformatic pipeline frameworks. Brief Bioinform (2017) 0.98
The COPD Knowledge Base: enabling data analysis and computational simulation in translational COPD research. J Transl Med (2014) 0.95
Big biomedical data as the key resource for discovery science. J Am Med Inform Assoc (2015) 0.95
ApiNATOMY: a novel toolkit for visualizing multiscale anatomy schematics with phenotype-related information. Hum Mutat (2012) 0.94
Big data in medicine is driving big changes. Yearb Med Inform (2014) 0.94
A comprehensive map of the influenza A virus replication cycle. BMC Syst Biol (2013) 0.93
Genomics Virtual Laboratory: A Practical Bioinformatics Workbench for the Cloud. PLoS One (2015) 0.93
Acute and chronic cognitive effects of levodopa and dopamine agonists on patients with Parkinson's disease: a review. Ther Adv Psychopharmacol (2013) 0.92
tranSMART: An Open Source Knowledge Management and High Content Data Analytics Platform. AMIA Jt Summits Transl Sci Proc (2014) 0.89
Atlas of Cancer Signalling Network: a systems biology resource for integrative analysis of cancer data with Google Maps. Oncogenesis (2015) 0.88
Connecting the dots: applications of network medicine in pharmacology and disease. Clin Pharmacol Ther (2013) 0.88
Network-based identification of biomarkers coexpressed with multiple pathways. Cancer Inform (2014) 0.88
Advances in analysis of transcriptional regulatory networks. Wiley Interdiscip Rev Syst Biol Med (2010) 0.88
BRISK--research-oriented storage kit for biology-related data. Bioinformatics (2011) 0.87
Algorithms and tools for protein-protein interaction networks clustering, with a special focus on population-based stochastic methods. Bioinformatics (2014) 0.87
Big Data Application in Biomedical Research and Health Care: A Literature Review. Biomed Inform Insights (2016) 0.86
A collaborative approach to develop a multi-omics data analytics platform for translational research. Appl Transl Genom (2014) 0.84
BiNA: a visual analytics tool for biological network data. PLoS One (2014) 0.84
PathVar: analysis of gene and protein expression variance in cellular pathways using microarray data. Bioinformatics (2011) 0.84
High dimensional biological data retrieval optimization with NoSQL technology. BMC Genomics (2014) 0.83
Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders. Int J Mol Sci (2015) 0.83
The big medical data miss: challenges in establishing an open medical resource. Nat Rev Genet (2015) 0.83
NaviCell Web Service for network-based data visualization. Nucleic Acids Res (2015) 0.82
Creating reusable tools from scripts: the Galaxy Tool Factory. Bioinformatics (2012) 0.79
Big data in biomedicine: 4 big questions. Nature (2015) 0.78
Integration of Administrative, Clinical, and Environmental Data to Support the Management of Type 2 Diabetes Mellitus: From Satellites to Clinical Care. J Diabetes Sci Technol (2015) 0.78
Platform for Personalized Oncology: Integrative analyses reveal novel molecular signatures associated with colorectal cancer relapse. AMIA Jt Summits Transl Sci Proc (2013) 0.78
Traits and types of health data repositories. Health Inf Sci Syst (2014) 0.77
From the desktop to the grid: scalable bioinformatics via workflow conversion. BMC Bioinformatics (2016) 0.76
Design, implementation and operation of a multimodality research imaging informatics repository. Health Inf Sci Syst (2015) 0.76
From Molecules to Patients: The Clinical Applications of Translational Bioinformatics. Yearb Med Inform (2015) 0.76