Published in Clin Epigenetics on July 26, 2016
Epigenetics in cancer. N Engl J Med (2008) 17.36
GAGE: A critical evaluation of genome assemblies and assembly algorithms. Genome Res (2012) 11.33
Principles and challenges of genomewide DNA methylation analysis. Nat Rev Genet (2010) 10.71
Epigenome-wide association studies for common human diseases. Nat Rev Genet (2011) 7.96
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res (2004) 7.92
Intra-individual change over time in DNA methylation with familial clustering. JAMA (2008) 6.17
Quantitative comparison of genome-wide DNA methylation mapping technologies. Nat Biotechnol (2010) 5.96
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat Neurosci (2012) 4.71
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Hum Mol Genet (2009) 4.25
Accounting for cellular heterogeneity is critical in epigenome-wide association studies. Genome Biol (2014) 3.89
Factors underlying variable DNA methylation in a human community cohort. Proc Natl Acad Sci U S A (2012) 3.20
Epigenetic modifications in pluripotent and differentiated cells. Nat Biotechnol (2010) 3.02
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. Hum Mol Genet (2009) 2.85
Intra- and interindividual epigenetic variation in human germ cells. Am J Hum Genet (2006) 2.79
The DNA methylation landscape of human early embryos. Nature (2014) 2.67
A study of the influence of sex on genome wide methylation. PLoS One (2010) 2.57
Precision of pyrosequencing assay to measure LINE-1 methylation in colon cancer, normal colonic mucosa, and peripheral blood cells. J Mol Diagn (2010) 2.15
Mechanisms involved in the developmental programming of adulthood disease. Biochem J (2010) 1.95
Maternal tobacco use modestly alters correlated epigenome-wide placental DNA methylation and gene expression. Epigenetics (2011) 1.76
Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation. Proc Natl Acad Sci U S A (2008) 1.74
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations. Nat Genet (2013) 1.70
Methylome analysis using MeDIP-seq with low DNA concentrations. Nat Protoc (2012) 1.70
Interindividual variability and parent of origin DNA methylation differences at specific human Alu elements. Hum Mol Genet (2005) 1.65
Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors. Genome Res (2011) 1.60
Global DNA hypomethylation is associated with in utero exposure to cotinine and perfluorinated alkyl compounds. Epigenetics (2010) 1.57
Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans. Genome Res (2012) 1.45
Epigenetic regulation of the neural transcriptome: the meaning of the marks. Nat Neurosci (2010) 1.44
MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments. Bioinformatics (2013) 1.38
Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type. BMC Genomics (2014) 1.34
Epigenetic aberrations in leukocytes of patients with schizophrenia: association of global DNA methylation with antipsychotic drug treatment and disease onset. FASEB J (2012) 1.33
DNA methylation and healthy human aging. Aging Cell (2015) 1.27
A comparison of the whole genome approach of MeDIP-seq to the targeted approach of the Infinium HumanMethylation450 BeadChip(®) for methylome profiling. PLoS One (2012) 1.16
The use of DNA from archival dried blood spots with the Infinium HumanMethylation450 array. BMC Biotechnol (2013) 1.09
Analysis of epigenetic changes in survivors of preterm birth reveals the effect of gestational age and evidence for a long term legacy. Genome Med (2013) 1.06
DNA methylome profiling using neonatal dried blood spot samples: a proof-of-principle study. Mol Genet Metab (2013) 1.03
DNA methylation signatures triggered by prenatal maternal stress exposure to a natural disaster: Project Ice Storm. PLoS One (2014) 1.02
High quality genome-wide genotyping from archived dried blood spots without DNA amplification. PLoS One (2013) 1.02
Archived neonatal dried blood spot samples can be used for accurate whole genome and exome-targeted next-generation sequencing. Mol Genet Metab (2013) 1.00
Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes. Epigenetics (2015) 1.00
Removing unwanted variation in a differential methylation analysis of Illumina HumanMethylation450 array data. Nucleic Acids Res (2015) 0.96
Testing two models describing how methylome-wide studies in blood are informative for psychiatric conditions. Epigenomics (2013) 0.94
High quality methylome-wide investigations through next-generation sequencing of DNA from a single archived dry blood spot. Epigenetics (2013) 0.91
Epigenetic mechanisms and genome stability. Clin Epigenetics (2011) 0.89
DNA methylation in schizophrenia: progress and challenges of epigenetic studies. Genome Med (2012) 0.89
Correlation of DNA methylation levels in blood and saliva DNA in young girls of the LEGACY Girls study. Epigenetics (2014) 0.87
Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling. BMC Biotechnol (2014) 0.87
Meta-analysis of human methylation data for evidence of sex-specific autosomal patterns. BMC Genomics (2014) 0.87
Profiling DNA methylome landscapes of mammalian cells with single-cell reduced-representation bisulfite sequencing. Nat Protoc (2015) 0.86
Characterization of the DNA methylome and its interindividual variation in human peripheral blood monocytes. Epigenomics (2013) 0.86
A systematic evaluation of whole genome amplification of bisulfite-modified DNA. Clin Epigenetics (2012) 0.85
Re-annotation of presumed noncoding disease/trait-associated genetic variants by integrative analyses. Sci Rep (2015) 0.81
Methylated DNA immunoprecipitation and high-throughput sequencing (MeDIP-seq) using low amounts of genomic DNA. Cell Reprogram (2014) 0.78