Interaction Between Peroxisome Proliferator Activated Receptor δ and Epithelial Membrane Protein 2 Polymorphisms Influences HDL-C Levels in the Chinese Population.

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Published in Ann Hum Genet on September 01, 2016

Authors

Tingjing Ke1, Rajkumar Dorajoo2, Yi Han1, Chiea-Chuen Khor2, Rob M van Dam3, Jian-Min Yuan4,5, Woon-Puay Koh3,6, Jianjun Liu2, Yik Ying Teo3,7, Daniel Y T Goh1, E Shyong Tai3, Tien Yin Wong8,9, Ching-Yu Cheng8,10, Yechiel Friedlander11, Chew-Kiat Heng1

Author Affiliations

1: Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore and Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore.
2: Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore.
3: Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
4: Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
5: Division of Cancer Control and Population Sciences, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.
6: Duke-NUS Graduate Medical School, Singapore.
7: Department of Statistics and Applied Probability, National University of Singapore, Singapore.
8: Singapore National Eye Centre, Singapore Eye Research Institute, Singapore.
9: Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
10: Academic Medicine Research Institute, Duke-NUS Graduate Medical School, National University of Singapore, Singapore.
11: School of Public Health and Community Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Associated clinical trials:

An Exploratory Study To Look At The Effect Of Two Investigational Drugs On Body Fat And Inflammation | NCT00388180

GW501516 In Subjects Who Have Low Level Of High-Density Lipoprotein Cholesterol | NCT00158899

Safety and Benefit of MBX-8025 With and Without Commonly Used Statins in Moderately Overweight Patients With High Cholesterol (MBX-8025) | NCT00701883

Regulation of Lipoprotein Transport in Metabolic Syndrome | NCT00841217

Study to Evaluate the Effects of MBX-8025 in Patients With HoFH | NCT02472535

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