Redirecting Specificity of T cells Using the Sleeping Beauty System to Express Chimeric Antigen Receptors by Mix-and-Matching of VL and VH Domains Targeting CD123+ Tumors.

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Published in PLoS One on August 22, 2016

Authors

Radhika Thokala1,2, Simon Olivares1, Tiejuan Mi1, Sourindra Maiti1, Drew Deniger1,3, Helen Huls4, Hiroki Torikai1, Harjeet Singh1, Richard E Champlin5, Tamara Laskowski1, George McNamara1, Laurence J N Cooper1,6

Author Affiliations

1: Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
2: The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas, United States of America.
3: Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
4: Intrexon Corporation, Germantown, Maryland, United States of America.
5: Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
6: Ziopharm Oncology Inc., Boston, Massachusetts, United States of America.

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