Published in Oncotarget on October 04, 2016
Roles of Mesenchymal Stem Cells in Spinal Cord Injury. Stem Cells Int (2017) 0.75
Muscle pathology from stochastic low level DUX4 expression in an FSHD mouse model. Nat Commun (2017) 0.75
HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science (1996) 26.19
Personalized copy number and segmental duplication maps using next-generation sequencing. Nat Genet (2009) 11.73
The biology of chemokines and their receptors. Annu Rev Immunol (2000) 9.81
Chemokines and leukocyte traffic. Nature (1998) 9.79
Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques (2002) 7.56
The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature (1998) 7.38
Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. J Biol Chem (2001) 7.35
CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood (2005) 5.21
Lymphocyte traffic control by chemokines. Nat Immunol (2001) 4.86
Molecular cloning and structure of a pre-B-cell growth-stimulating factor. Proc Natl Acad Sci U S A (1994) 4.25
The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells (2007) 3.68
DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1. Proc Natl Acad Sci U S A (2007) 3.32
CXC chemokines in angiogenesis. J Leukoc Biol (2000) 3.17
Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element. Gene (1999) 3.00
Facioscapulohumeral dystrophy: incomplete suppression of a retrotransposed gene. PLoS Genet (2010) 2.95
The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein. Neuromuscul Disord (2007) 2.85
An isogenetic myoblast expression screen identifies DUX4-mediated FSHD-associated molecular pathologies. EMBO J (2008) 2.74
Chemokines and chemokine receptors: positioning cells for host defense and immunity. Annu Rev Immunol (2014) 2.71
Classification and nomenclature of all human homeobox genes. BMC Biol (2007) 2.61
Analysis of the tandem repeat locus D4Z4 associated with facioscapulohumeral muscular dystrophy. Hum Mol Genet (1994) 2.60
Chemokines and the molecular basis of cancer metastasis. N Engl J Med (2001) 2.60
RNA transcripts, miRNA-sized fragments and proteins produced from D4Z4 units: new candidates for the pathophysiology of facioscapulohumeral dystrophy. Hum Mol Genet (2009) 2.51
Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation. Hum Mol Genet (2006) 2.51
A review on CXCR4/CXCL12 axis in oncology: no place to hide. Eur J Cancer (2012) 2.39
The elusive nature and function of mesenchymal stem cells. Nat Rev Mol Cell Biol (2011) 2.31
Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation. Cancer Res (2006) 2.18
DUX4 activates germline genes, retroelements, and immune mediators: implications for facioscapulohumeral dystrophy. Dev Cell (2011) 2.17
The chemokine SDF1/CXCL12 and its receptor CXCR4 regulate mouse germ cell migration and survival. Development (2003) 2.13
Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy. Am J Hum Genet (2007) 2.06
CXC chemokines in angiogenesis. Cytokine Growth Factor Rev (2005) 2.00
Cellular senescence in human myoblasts is overcome by human telomerase reverse transcriptase and cyclin-dependent kinase 4: consequences in aging muscle and therapeutic strategies for muscular dystrophies. Aging Cell (2007) 1.98
Role of the alpha-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system. Glia (2003) 1.94
Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases. Hum Mol Genet (2003) 1.93
DUX4, a candidate gene for facioscapulohumeral muscular dystrophy, causes p53-dependent myopathy in vivo. Ann Neurol (2010) 1.89
Trafficking and differentiation of mesenchymal stem cells. J Cell Biochem (2009) 1.81
Chemokines and chemokine receptors: their manifold roles in homeostasis and disease. Cell Mol Immunol (2004) 1.75
Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults. Nat Genet (2016) 1.71
Chemokines: key players in innate and adaptive immunity. J Invest Dermatol (2005) 1.55
Chemokine signaling in embryonic cell migration: a fisheye view. Development (2009) 1.50
DUX4c, an FSHD candidate gene, interferes with myogenic regulators and abolishes myoblast differentiation. Exp Neurol (2008) 1.48
Defining the origins and evolution of the chemokine/chemokine receptor system. J Immunol (2006) 1.48
The FSHD atrophic myotube phenotype is caused by DUX4 expression. PLoS One (2011) 1.45
Myoblasts from affected and non-affected FSHD muscles exhibit morphological differentiation defects. J Cell Mol Med (2008) 1.42
CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells. Genes Dev (2005) 1.40
Stromal-derived factor-1/CXCR4 signaling: indispensable role in homing and engraftment of hematopoietic stem cells in bone marrow. Stem Cells Dev (2011) 1.37
The surface adhesion molecule CXCR4 stimulates mesenchymal stem cell migration to stromal cell-derived factor-1 in vitro but does not decrease apoptosis under serum deprivation. Cardiovasc Revasc Med (2006) 1.35
Testing the effects of FSHD candidate gene expression in vertebrate muscle development. Int J Clin Exp Pathol (2010) 1.34
The CIC-DUX4 fusion transcript is present in a subgroup of pediatric primitive round cell sarcomas. Hum Pathol (2011) 1.29
Inflammatory response in facioscapulohumeral muscular dystrophy (FSHD): immunocytochemical and genetic analyses. Muscle Nerve Suppl (1995) 1.23
Involvement of the CXCL12/CXCR4 pathway in the advanced liver disease that is associated with hepatitis C virus or hepatitis B virus. Eur J Immunol (2004) 1.20
The roles of mesenchymal stem cells in tumor inflammatory microenvironment. J Hematol Oncol (2014) 1.20
Intrinsic epigenetic regulation of the D4Z4 macrosatellite repeat in a transgenic mouse model for FSHD. PLoS Genet (2013) 1.19
Enhancing the migration ability of mesenchymal stromal cells by targeting the SDF-1/CXCR4 axis. Biomed Res Int (2013) 1.19
Annotation, nomenclature and evolution of four novel homeobox genes expressed in the human germ line. Gene (2006) 1.18
CXC chemokine ligand 12 (CXCL12) and its receptor CXCR4. J Mol Med (Berl) (2014) 1.16
The dynamics of vertebrate homeobox gene evolution: gain and loss of genes in mouse and human lineages. BMC Evol Biol (2011) 1.13
DUX4c is up-regulated in FSHD. It induces the MYF5 protein and human myoblast proliferation. PLoS One (2009) 1.12
Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements. Gene (2001) 1.10
Mice deficient in the chemokine receptor CXCR4 exhibit impaired limb innervation and myogenesis. Mol Cell Neurosci (2005) 1.06
Involvement of CXCR4/CXCR7/CXCL12 Interactions in Inflammatory bowel disease. Theranostics (2013) 1.06
DUX4-induced gene expression is the major molecular signature in FSHD skeletal muscle. Hum Mol Genet (2014) 1.06
Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl. Dev Dyn (2010) 1.05
Characterization of a double homeodomain protein (DUX1) encoded by a cDNA homologous to 3.3 kb dispersed repeated elements. Hum Mol Genet (1998) 1.04
Expression of DUX4 in zebrafish development recapitulates facioscapulohumeral muscular dystrophy. Hum Mol Genet (2012) 1.02
The role of mesenchymal stem cells in cancer development. Front Genet (2013) 1.02
Immunodetection of human double homeobox 4. Hybridoma (Larchmt) (2011) 1.00
The chemokine SDF1 controls multiple steps of myogenesis through atypical PKCzeta. J Cell Sci (2007) 0.99
Dominant lethal pathologies in male mice engineered to contain an X-linked DUX4 transgene. Cell Rep (2014) 0.98
Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development. J Immunol (2007) 0.96
Induction of myogenic differentiation by SDF-1 via CXCR4 and CXCR7 receptors. Muscle Nerve (2010) 0.94
Fine mapping of the FSHD gene region orientates the rearranged fragment detected by the probe p13E-11. Hum Mol Genet (1993) 0.94
Sdf-1 (CXCL12) improves skeletal muscle regeneration via the mobilisation of Cxcr4 and CD34 expressing cells. Biol Cell (2012) 0.93
Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors. J Immunol (2015) 0.91
Catalytic roles of yeast GSK3beta/shaggy homolog Rim11p in meiotic activation. Genetics (1999) 0.91
Regulation of hematopoiesis by chemokine family members. Int J Hematol (2001) 0.90
Inhibitors of CXC chemokine receptor type 4: putative therapeutic approaches in inflammatory diseases. Curr Opin Hematol (2014) 0.89
Chemokines and Their Receptors Are Key Players in the Orchestra That Regulates Wound Healing. Adv Wound Care (New Rochelle) (2013) 0.89
Inhibitors of CXCR4 affect the migration and fate of CXCR4+ progenitors in the developing limb of chick embryos. Dev Dyn (2006) 0.88
DUX4 differentially regulates transcriptomes of human rhabdomyosarcoma and mouse C2C12 cells. PLoS One (2013) 0.88
Attractive guidance: how the chemokine SDF1/CXCL12 guides different cells to different locations. Semin Cell Dev Biol (2012) 0.86
Defective regulation of microRNA target genes in myoblasts from facioscapulohumeral dystrophy patients. J Biol Chem (2013) 0.85
Hypermethylation of genomic 3.3-kb repeats is frequent event in HPV-positive cervical cancer. BMC Med Genomics (2009) 0.85
The chemokine system in innate immunity. Cold Spring Harb Perspect Biol (2015) 0.85
Fusion of EWSR1 with the DUX4 facioscapulohumeral muscular dystrophy region resulting from t(4;22)(q35;q12) in a case of embryonal rhabdomyosarcoma. Cancer Genet Cytogenet (2009) 0.85
Multiple protein domains contribute to nuclear import and cell toxicity of DUX4, a candidate pathogenic protein for facioscapulohumeral muscular dystrophy. PLoS One (2013) 0.83
Expression of the human FSHD-linked DUX4 gene induces neurogenesis during differentiation of murine embryonic stem cells. Stem Cells Dev (2013) 0.81
Dux4 induces cell cycle arrest at G1 phase through upregulation of p21 expression. Biochem Biophys Res Commun (2014) 0.80
Double homeobox gene, Duxbl, promotes myoblast proliferation and abolishes myoblast differentiation by blocking MyoD transactivation. Cell Tissue Res (2014) 0.80
Expression of FSHD-related DUX4-FL alters proteostasis and induces TDP-43 aggregation. Ann Clin Transl Neurol (2015) 0.79
CXC and CC chemokines as angiogenic modulators in nonhaematological tumors. Biomed Res Int (2014) 0.78
Loss of epigenetic silencing of the DUX4 transcription factor gene in facioscapulohumeral muscular dystrophy. Hum Mol Genet (2015) 0.78
Retrograde migration of pectoral girdle muscle precursors depends on CXCR4/SDF-1 signaling. Histochem Cell Biol (2014) 0.76