SIRT1-mediated FoxOs pathways protect against apoptosis by promoting autophagy in osteoblast-like MC3T3-E1 cells exposed to sodium fluoride.

PubWeight™: 0.77‹?›

🔗 View Article (PMID 27564107)

Published in Oncotarget on October 04, 2016

Authors

Xiaolong Gu1, Dandan Han1, Wei Chen1, Limei Zhang1, Qianyun Lin1, Jian Gao1, Séamus Fanning2, Bo Han1

Author Affiliations

1: College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing 100193, P R China.
2: UCD-Centre for Food Safety, School of Public Health, Physiotherapy and Sports Science, University College Dublin, Belfield, Dublin 4, Ireland.

Articles cited by this

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science (2004) 17.38

FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab (2007) 8.90

Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem (1999) 8.16

Sirtuins in mammals: insights into their biological function. Biochem J (2007) 7.60

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Natl Acad Sci U S A (2008) 5.48

Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ (2009) 5.28

Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity. Proc Natl Acad Sci U S A (2004) 3.93

FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1). J Biol Chem (2004) 3.39

Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival. Cancer Res (2005) 2.94

Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells. Oncogene (2006) 2.74

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes. Circ Res (2010) 2.57

FoxO transcription factors promote autophagy in cardiomyocytes. J Biol Chem (2009) 2.40

FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress. J Biol Chem (2010) 2.00

Regulation of SIRT1 in cellular functions: role of polyphenols. Arch Biochem Biophys (2010) 1.91

A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells. Biochem Biophys Res Commun (2008) 1.52

Autophagy and apoptosis: where do they meet? Apoptosis (2014) 1.42

Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD. Arch Biochem Biophys (2010) 1.34

SIRT1: tumor promoter or tumor suppressor? Med Hypotheses (2006) 1.33

Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells. Free Radic Biol Med (2001) 1.19

SIRT1: roles in aging and cancer. BMB Rep (2008) 1.13

Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria. J Neurochem (2000) 1.09

A review of Sirt1 and Sirt1 modulators in cardiovascular and metabolic diseases. Recent Pat Cardiovasc Drug Discov (2008) 0.98

Involvement of both mitochondrial- and death receptor-dependent apoptotic pathways regulated by Bcl-2 family in sodium fluoride-induced apoptosis of the human gingival fibroblasts. Toxicology (2007) 0.97

Mitochondrial autophagy protects against heat shock-induced apoptosis through reducing cytosolic cytochrome c release and downstream caspase-3 activation. Biochem Biophys Res Commun (2010) 0.96

Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1. Acta Pharmacol Sin (2011) 0.96

Sirtuin1 and autophagy protect cells from fluoride-induced cell stress. Biochim Biophys Acta (2013) 0.93

Fluoride induces oxidative damage and SIRT1/autophagy through ROS-mediated JNK signaling. Free Radic Biol Med (2015) 0.93

Fluoride induces apoptosis by caspase-3 activation in human leukemia HL-60 cells. Arch Toxicol (2000) 0.79