Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma.

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🔗 View Article (PMID 27571927)

Published in Nat Commun on August 30, 2016

Authors

Jeffrey J Wallin1, Johanna C Bendell2, Roel Funke1, Mario Sznol3, Konstanty Korski4, Suzanne Jones2, Genevive Hernandez1, James Mier5, Xian He1, F Stephen Hodi6, Mitchell Denker1, Vincent Leveque1, Marta Cañamero4, Galina Babitski4, Hartmut Koeppen1, James Ziai1, Neeraj Sharma1, Fabien Gaire4, Daniel S Chen1, Daniel Waterkamp1, Priti S Hegde1, David F McDermott5

Author Affiliations

1: Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
2: GI Oncology Research, Drug Development Unit, Sarah Cannon Research Institute, 250 25th Avenue North, Suite 100, Nashville, Tennessee, 37203, USA.
3: Department of Internal Medicine and Melanoma Unit, Yale Cancer Center, New Haven, Connecticut 06511, USA.
4: Roche Diagnostics GmbH, Nonnenwald 2, 82377 Penzberg, Germany.
5: Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusets 02215, USA.
6: Dana-Farber/Brigham and Women's Cancer Center, 450 Brookline Avenue, Boston, Massachusets 02215, USA.

Associated clinical trials:

A Study of Atezolizumab Administered in Combination With Bevacizumab and/or With Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors | NCT01633970

BEAT-meso: Bevacizumab and Atezolizumab in Malignant Pleural Mesothelioma (BEAT-meso) | NCT03762018

Efficacy and Safety of Tislelizumab Combined With Bevacizumab and Albumin Paclitaxel in Lung Adenocarcinoma | NCT04310943

Sintilimab Injection Combined With Inlyta in Fumarate Hydratase- Deficient Renal Cell Carcinoma | NCT04387500

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