Mechanisms of heparanase inhibitors in cancer therapy.

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Published in Exp Hematol on August 26, 2016

Authors

Benjamin Heyman1, Yiping Yang2

Author Affiliations

1: Division of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University, Durham, North Carolina, USA.
2: Division of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University, Durham, North Carolina, USA; Department of Immunology, Duke University, Durham, North Carolina, USA. Electronic address: yang0029@mc.duke.edu.

Associated clinical trials:

M402 in Combination With Nab-Paclitaxel and Gemcitabine in Pancreatic Cancer | NCT01621243

SST0001 (Roneparstat) in Advanced Multiple Myeloma | NCT01764880

Study of the Safety and Tolerability of IV Infused PG545 in Patients With Advanced Solid Tumours | NCT02042781

A Phase III Study of PI-88 in the Adjuvant Treatment of Subjects With Hepatitis Virus Related Hepatocellular Carcinoma After Surgical Resection (PATRON) | NCT01402908

Melphalan, Prednisone, Thalidomide and Defibrotide in Relapsed Multiple Myeloma Patients (MPTD) | NCT00406978

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