Published in PLoS One on September 08, 2016
Derivation of human embryonic stem cells in defined conditions. Nat Biotechnol (2006) 8.28
Feeder-independent culture of human embryonic stem cells. Nat Methods (2006) 7.61
A more efficient method to generate integration-free human iPS cells. Nat Methods (2011) 7.39
Chemically defined conditions for human iPSC derivation and culture. Nat Methods (2011) 5.84
Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. Mol Cell (2000) 5.72
Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells. J Cell Sci (2005) 4.86
Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells. Cell Stem Cell (2010) 4.59
Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511. Nat Biotechnol (2010) 3.70
Structural basis for FGF receptor dimerization and activation. Cell (1999) 3.19
Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers. Stem Cells (2005) 3.05
Lab-specific gene expression signatures in pluripotent stem cells. Cell Stem Cell (2010) 2.95
Feeder layer- and serum-free culture of human embryonic stem cells. Biol Reprod (2003) 2.89
Basic fibroblast growth factor support of human embryonic stem cell self-renewal. Stem Cells (2005) 2.78
Lack of immune response to differentiated cells derived from syngeneic induced pluripotent stem cells. Cell Stem Cell (2013) 2.45
Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells. Stem Cells (2006) 2.37
An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells. Stem Cells (2013) 2.18
FGF2 sustains NANOG and switches the outcome of BMP4-induced human embryonic stem cell differentiation. Cell Stem Cell (2011) 2.11
Defined culture conditions of human embryonic stem cells. Proc Natl Acad Sci U S A (2006) 2.09
MEK/ERK signaling contributes to the maintenance of human embryonic stem cell self-renewal. Differentiation (2007) 1.83
A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells. Sci Rep (2014) 1.81
Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment. Nat Commun (2014) 1.56
A complex role for FGF-2 in self-renewal, survival, and adhesion of human embryonic stem cells. Stem Cells (2009) 1.46
Generation of integration-free human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression. Nat Protoc (2012) 1.32
Secreted proteoglycans directly mediate human embryonic stem cell-basic fibroblast growth factor 2 interactions critical for proliferation. Stem Cells (2008) 1.01
Significant variations in differentiation properties between independent mouse ES cell lines cultured under defined conditions. Exp Cell Res (2004) 0.97
Monolayer culturing and cloning of human pluripotent stem cells on laminin-521-based matrices under xeno-free and chemically defined conditions. Nat Protoc (2014) 0.90
Differentiation of human embryonic stem cells in adherent and in chemically defined culture conditions. Curr Protoc Stem Cell Biol (2008) 0.90
Sustained levels of FGF2 maintain undifferentiated stem cell cultures with biweekly feeding. PLoS One (2013) 0.85
Scalable passaging of adherent human pluripotent stem cells. PLoS One (2014) 0.82
cGMP-Manufactured Human Induced Pluripotent Stem Cells Are Available for Pre-clinical and Clinical Applications. Stem Cell Reports (2015) 0.81