Published in Metabolomics on September 02, 2016
Metabolomics Predict Therapy Response (PROLUNG) | NCT03736993
Reconciling evidence-based medicine and precision medicine in the era of big data: challenges and opportunities. Genome Med (2016) 0.83
The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine. Antioxid Redox Signal (2017) 0.79
Dynamic and temporal assessment of human dried blood spot MS/MS(ALL) shotgun lipidomics analysis. Nutr Metab (Lond) (2017) 0.77
Crossing the Boundaries of Our Current Healthcare System by Integrating Ultra-Weak Photon Emissions with Metabolomics. Front Physiol (2016) 0.75
Stability of targeted metabolite profiles of urine samples under different storage conditions. Metabolomics (2016) 0.75
Considerations when choosing a genetic model organism for metabolomics studies. Curr Opin Chem Biol (2016) 0.75
Biomarkers are used to predict quantitative metabolite concentration profiles in human red blood cells. PLoS Comput Biol (2017) 0.75
Integrated Metabolomics Assessment of Human Dried Blood Spots and Urine Strips. Metabolites (2017) 0.75
Specific Genes Associated with Adverse Events of Methylphenidate Use in the Pediatric Population: A Systematic Literature Review. J Res Pharm Pract (2017) 0.75
Environmental influences in the etiology of colorectal cancer: the premise of metabolomics. Curr Pharmacol Rep (2017) 0.75
NMR-based Stable Isotope Resolved Metabolomics in systems biochemistry. Arch Biochem Biophys (2017) 0.75
A new initiative on precision medicine. N Engl J Med (2015) 16.03
Human metabolic individuality in biomedical and pharmaceutical research. Nature (2011) 6.56
Succinate is an inflammatory signal that induces IL-1β through HIF-1α. Nature (2013) 5.44
Gut microorganisms, mammalian metabolism and personalized health care. Nat Rev Microbiol (2005) 5.35
Innovation: Metabolomics: the apogee of the omics trilogy. Nat Rev Mol Cell Biol (2012) 5.19
A community-driven global reconstruction of human metabolism. Nat Biotechnol (2013) 3.89
Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell (2015) 3.67
Metabolomics: a global biochemical approach to drug response and disease. Annu Rev Pharmacol Toxicol (2008) 3.48
Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature (2006) 3.45
An atlas of genetic influences on human blood metabolites. Nat Genet (2014) 3.21
Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proc Natl Acad Sci U S A (2009) 3.01
Randomised clinical trial: gut microbiome biomarkers are associated with clinical response to a low FODMAP diet in children with the irritable bowel syndrome. Aliment Pharmacol Ther (2015) 2.87
Expanded newborn screening for inborn errors of metabolism by electrospray ionization-tandem mass spectrometry: results, outcome, and implications. Pediatrics (2003) 2.66
Use of genome-wide association studies for drug repositioning. Nat Biotechnol (2012) 2.51
Energy balance measurement: when something is not better than nothing. Int J Obes (Lond) (2014) 2.51
Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy. Chem Soc Rev (2010) 2.50
Antibiotic use and inflammatory bowel diseases in childhood. Gut (2010) 2.48
Metabolomics reveals metabolic biomarkers of Crohn's disease. PLoS One (2009) 2.35
Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research. Metabolomics (2009) 2.21
Translational biomarker discovery in clinical metabolomics: an introductory tutorial. Metabolomics (2012) 2.18
The challenges of modeling mammalian biocomplexity. Nat Biotechnol (2004) 2.03
An invitation to the marriage of metagenomics and metabolomics. Cell (2008) 1.86
A genome-wide association study of metabolic traits in human urine. Nat Genet (2011) 1.84
Metabolomic mapping of atypical antipsychotic effects in schizophrenia. Mol Psychiatry (2007) 1.78
Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics. Clin Pharmacol Ther (2010) 1.74
Translational biomarkers of acetaminophen-induced acute liver injury. Arch Toxicol (2015) 1.49
A GC-TOF-MS study of the stability of serum and urine metabolomes during the UK Biobank sample collection and preparation protocols. Int J Epidemiol (2008) 1.40
High-throughput 1H NMR-based metabolic analysis of human serum and urine for large-scale epidemiological studies: validation study. Int J Epidemiol (2008) 1.39
Genetic variation in metabolic phenotypes: study designs and applications. Nat Rev Genet (2012) 1.38
Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics. Pharmacogenet Genomics (2012) 1.34
Xenobiotic metabolomics: major impact on the metabolome. Annu Rev Pharmacol Toxicol (2011) 1.34
Pretreatment metabotype as a predictor of response to sertraline or placebo in depressed outpatients: a proof of concept. Transl Psychiatry (2011) 1.32
Opening up the "Black Box": metabolic phenotyping and metabolome-wide association studies in epidemiology. J Clin Epidemiol (2010) 1.31
Enteric microbiome metabolites correlate with response to simvastatin treatment. PLoS One (2011) 1.31
The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans. Bioanalysis (2012) 1.29
Stable isotope-resolved metabolomics and applications for drug development. Pharmacol Ther (2011) 1.29
Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study. Metabolomics (2010) 1.29
Metabolomics of a superorganism. J Nutr (2007) 1.24
Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment. PLoS One (2012) 1.22
Defining the metabolome: size, flux, and regulation. Mol Cell (2015) 1.11
Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology. Clin Pharmacol Ther (2013) 1.11
Pharmacometabolomics reveals racial differences in response to atenolol treatment. PLoS One (2013) 1.10
Purine pathway implicated in mechanism of resistance to aspirin therapy: pharmacometabolomics-informed pharmacogenomics. Clin Pharmacol Ther (2013) 1.10
Systematic prediction of health-relevant human-microbial co-metabolism through a computational framework. Gut Microbes (2015) 1.08
Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry. Trends Analyt Chem (2014) 1.08
Use of pharmaco-metabonomics for early prediction of acetaminophen-induced hepatotoxicity in humans. Clin Pharmacol Ther (2010) 1.08
The Relationship Between Trimethylamine-N-Oxide and Prevalent Cardiovascular Disease in a Multiethnic Population Living in Canada. Can J Cardiol (2015) 1.06
Untargeted plasma metabolite profiling reveals the broad systemic consequences of xanthine oxidoreductase inactivation in mice. PLoS One (2012) 1.03
Metabolomics view on gut microbiome modulation by polyphenol-rich foods. J Proteome Res (2012) 1.03
Molecular phenotyping of a UK population: defining the human serum metabolome. Metabolomics (2014) 1.02
Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer. Elife (2014) 1.01
Dietary lignans: physiology and potential for cardiovascular disease risk reduction. Nutr Rev (2010) 1.00
Pharmacometabonomic profiling as a predictor of toxicity in patients with inoperable colorectal cancer treated with capecitabine. Clin Cancer Res (2011) 0.99
Drugs, bugs, and personalized medicine: pharmacometabonomics enters the ring. Proc Natl Acad Sci U S A (2009) 0.96
Food and drug interaction: consequences for the nutrition/health status. Ann Nutr Metab (2008) 0.94
Computational Modeling of Human Metabolism and Its Application to Systems Biomedicine. Methods Mol Biol (2016) 0.94
Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. Nat Commun (2015) 0.93
Integration of pharmacometabolomic and pharmacogenomic approaches reveals novel insights into antiplatelet therapy. Clin Pharmacol Ther (2013) 0.93
Influence of diet and nutritional status on drug metabolism. Clin Pharmacokinet (1996) 0.93
Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther (2015) 0.93
A metabolic phenotyping approach to understanding relationships between metabolic syndrome and breast tumour responses to chemotherapy. Ann Oncol (2011) 0.93
Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo. Transl Psychiatry (2013) 0.92
Pharmacometabolomics reveals that serotonin is implicated in aspirin response variability. CPT Pharmacometrics Syst Pharmacol (2014) 0.90
The development and validation of a fast and robust dried blood spot based lipid profiling method to study infant metabolism. Metabolomics (2014) 0.90
Pharmacometabonomics and personalized medicine. Ann Clin Biochem (2013) 0.89
The emergent role of metabolic phenotyping in dynamic patient stratification. Expert Opin Drug Metab Toxicol (2014) 0.89
Is diabetes mellitus-linked amino acid signature associated with β-blocker-induced impaired fasting glucose? Circ Cardiovasc Genet (2014) 0.88
Development of exposome correlation globes to map out environment-wide associations. Pac Symp Biocomput (2015) 0.88
Genetics of human metabolism: an update. Hum Mol Genet (2015) 0.87
TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics. Mol Psychiatry (2016) 0.86
Pharmacometabonomics in humans: a new tool for personalized medicine. Pharmacogenomics (2015) 0.86
Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism. Cell Rep (2015) 0.86
Pharmacometabolomics of statin response. Clin Pharmacol Ther (2013) 0.86
Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opin Drug Metab Toxicol (2012) 0.85
The changing face of newborn screening: diagnosis of inborn errors of metabolism by tandem mass spectrometry. Clin Chim Acta (2002) 0.84
Metabolomics as a tool in nutritional research. Curr Opin Lipidol (2015) 0.83
Biochemical insights from population studies with genetics and metabolomics. Arch Biochem Biophys (2015) 0.83
Innovation in metabolomics to improve personalized healthcare. Ann N Y Acad Sci (2015) 0.82
Determination of morphine and 6-acetylmorphine in blood with use of dried blood spots. Ther Drug Monit (2008) 0.82
Inborn Errors of Metabolism: Advances in Diagnosis and Therapy. JAMA Pediatr (2015) 0.80
A Pharmacometabonomic Approach To Predicting Metabolic Phenotypes and Pharmacokinetic Parameters of Atorvastatin in Healthy Volunteers. J Proteome Res (2015) 0.79
Personalized medicine in human space flight: using Omics based analyses to develop individualized countermeasures that enhance astronaut safety and performance. Metabolomics (2013) 0.79
Pharmacometabolomic Assessments of Atenolol and Hydrochlorothiazide Treatment Reveal Novel Drug Response Phenotypes. CPT Pharmacometrics Syst Pharmacol (2015) 0.79
Metabolomics to Explore Impact of Dairy Intake. Nutrients (2015) 0.78
The use of metabolomics in population-based research. Adv Nutr (2014) 0.78
Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study. J Am Heart Assoc (2015) 0.77
Lean-seafood intake decreases urinary markers of mitochondrial lipid and energy metabolism in healthy subjects: Metabolomics results from a randomized crossover intervention study. Mol Nutr Food Res (2016) 0.77
Discovery of nutritional biomarkers: future directions based on omics technologies. Int J Food Sci Nutr (2015) 0.77
Food metabolomics: from farm to human. Curr Opin Biotechnol (2015) 0.76
A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration. Hypertension (2016) 0.76
Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans. Front Pharmacol (2016) 0.76
Metabolomics by Gas Chromatography-Mass Spectrometry: Combined Targeted and Untargeted Profiling. Curr Protoc Mol Biol (2016) 0.76
Screening newborns for metabolic disorders based on targeted metabolomics using tandem mass spectrometry. Ann Pediatr Endocrinol Metab (2015) 0.75
PopPAnTe: population and pedigree association testing for quantitative data. BMC Genomics (2017) 0.75