Published in Circulation on September 01, 1989
Endothelium-mediated coronary blood flow modulation in humans. Effects of age, atherosclerosis, hypercholesterolemia, and hypertension. J Clin Invest (1993) 1.73
Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis. J Clin Invest (1995) 1.69
St Cyres lecture. Endothelium in control. Br Heart J (1991) 1.43
Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart. Proc Natl Acad Sci U S A (1994) 1.29
L-arginine normalizes endothelial function in cerebral vessels from hypercholesterolemic rabbits. J Clin Invest (1991) 1.15
Contribution of sympathetic activation to coronary vasodilatation during the cold pressor test in healthy men: effect of ageing. J Physiol (2013) 1.08
Microvascular coronary dysfunction in women: pathophysiology, diagnosis, and management. Curr Probl Cardiol (2011) 1.08
Role of PET in the evaluation and understanding of coronary physiology. J Nucl Cardiol (2007) 1.02
Nitric Oxide as a Unique Bioactive Signaling Messenger in Physiology and Pathophysiology. J Biomed Biotechnol (2004) 0.98
PET-measured heterogeneity in longitudinal myocardial blood flow in response to sympathetic and pharmacologic stress as a non-invasive probe of epicardial vasomotor dysfunction. Eur J Nucl Med Mol Imaging (2006) 0.94
Coronary flow reserve is supranormal in endurance athletes: an adenosine transthoracic echocardiographic study. Heart (2000) 0.90
Nitric oxide function in atherosclerosis. Mediators Inflamm (1997) 0.87
Flow associated or flow mediated dilatation? More than just semantics. Heart (1997) 0.87
Diagnostic value of PET-measured heterogeneity in myocardial blood flows during cold pressor testing for the identification of coronary vasomotor dysfunction. J Nucl Cardiol (2007) 0.86
Angina, "normal" coronary angiography, and vascular dysfunction: risk assessment strategies. PLoS Med (2007) 0.85
Resistive vessel function in coronary artery disease. Heart (1996) 0.81
Approaches for non-invasive assessment of endothelial function: focus on peripheral arterial tonometry. Neth Heart J (2013) 0.80
Endothelium dependent and independent responses in coronary artery disease measured at angioplasty. Br Heart J (1993) 0.75
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Assessment of endothelium-mediated vasodilation of the peripheral circulation by transcutaneous ultrasonography and venous occlusion plethysmography. Heart Vessels (1999) 0.75
Regulation of myocardial oxygen delivery. Intensive Care Med (1990) 0.75
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Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature (1999) 13.73
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Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med (1997) 6.17
Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation (2000) 6.13
Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation (2001) 5.87
A comparison of surgical and medical therapy for atrial septal defect in adults. N Engl J Med (1995) 4.99
HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway. J Clin Invest (2001) 4.11
Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circ Res (2001) 3.89
Association between thrombolytic treatment and the prognosis of hemodynamically stable patients with major pulmonary embolism: results of a multicenter registry. Circulation (1997) 3.58
Right ventricular infarction as an independent predictor of prognosis after acute inferior myocardial infarction. N Engl J Med (1993) 3.53
Nickel and molybdenum contact allergies in patients with coronary in-stent restenosis. Lancet (2000) 3.31
Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial. Lancet (2002) 3.18
Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCARE-AMI): mechanistic insights from serial contrast-enhanced magnetic resonance imaging. Circulation (2003) 2.97
Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease. Circulation (2001) 2.95
Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2+)-ATPase in failing and nonfailing human myocardium. Circ Res (1994) 2.82
Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases. J Exp Med (1997) 2.76
Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis. Circ Res (1998) 2.70
Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine. Lancet (1992) 2.66
Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis. Circulation (1991) 2.61
Alterations of skeletal muscle in chronic heart failure. Circulation (1992) 2.58
Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers : evidence for a dysfunctional nitric oxide synthase. Circ Res (2000) 2.52
Relationship between Na+-Ca2+-exchanger protein levels and diastolic function of failing human myocardium. Circulation (1999) 2.45
Platelet glycoprotein IIIa polymorphisms and risk of coronary stent thrombosis. Lancet (1997) 2.36
Alterations of sarcoplasmic reticulum proteins in failing human dilated cardiomyopathy. Circulation (1995) 2.27
Elevated C-reactive protein levels and impaired endothelial vasoreactivity in patients with coronary artery disease. Circulation (2000) 2.18
Quantitative assessment of coronary vasoreactivity in humans in vivo. Importance of baseline vasomotor tone in atherosclerosis. Circulation (1995) 2.16
Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway. Mol Cell Biol (2000) 2.07
Patent foramen ovale is an important predictor of adverse outcome in patients with major pulmonary embolism. Circulation (1998) 2.06
Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system. Circulation (1999) 2.05
Gene expression of the cardiac Na(+)-Ca2+ exchanger in end-stage human heart failure. Circ Res (1994) 2.04
Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway. J Exp Med (1999) 1.99
Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells. Mol Cell Biol (2001) 1.98
Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration. FEBS Lett (2000) 1.97
Akt takes center stage in angiogenesis signaling. Circ Res (2000) 1.96
Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy. Circulation (1995) 1.86
Nitric oxide inhibits caspase-3 by S-nitrosation in vivo. J Biol Chem (1999) 1.78
Coronary vasomotion in response to sympathetic stimulation in humans: importance of the functional integrity of the endothelium. J Am Coll Cardiol (1989) 1.75
Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus. Diabetologia (2000) 1.74
Endothelium-mediated coronary blood flow modulation in humans. Effects of age, atherosclerosis, hypercholesterolemia, and hypertension. J Clin Invest (1993) 1.73
Endothelial cell apoptosis in angiogenesis and vessel regression. Circ Res (2000) 1.73
Prognostic significance of right ventricular afterload stress detected by echocardiography in patients with clinically suspected pulmonary embolism. Heart (1997) 1.72
Nitric oxide-an endothelial cell survival factor. Cell Death Differ (1999) 1.70
PTCA registry of German community hospitals. Arbeitsgemeinschaft Leitender Kardiologischer Krankenhausärzte (ALKK) Study Group. Eur Heart J (1997) 1.69
Endothelial function in chronic congestive heart failure. Am J Cardiol (1992) 1.69
Antioxidant vitamin C improves endothelial dysfunction in chronic smokers. Circulation (1996) 1.67
Significance of ventricular arrhythmias in idiopathic dilated cardiomyopathy. Am J Cardiol (1984) 1.62
Endothelial dysfunction of the coronary microvasculature is associated with coronary blood flow regulation in patients with early atherosclerosis. Circulation (1991) 1.61
Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction. Circ Res (2000) 1.60
Shear stress inhibits apoptosis of human endothelial cells. FEBS Lett (1996) 1.58
Diminished post-rest potentiation of contractile force in human dilated cardiomyopathy. Functional evidence for alterations in intracellular Ca2+ handling. J Clin Invest (1996) 1.56
Influence of the force-frequency relationship on haemodynamics and left ventricular function in patients with non-failing hearts and in patients with dilated cardiomyopathy. Eur Heart J (1994) 1.54
Allele-specific regulation of matrix metalloproteinase-12 gene activity is associated with coronary artery luminal dimensions in diabetic patients with manifest coronary artery disease. Circ Res (2000) 1.52
Coronary angioplasty in octogenarians. Quality of life and costs. Eur Heart J (1999) 1.50
Prevalence, circumstances, mechanisms, and risk stratification of sudden cardiac death in unipolar single-chamber ventricular pacing. Circulation (1992) 1.50
Insulin-mediated stimulation of protein kinase Akt: A potent survival signaling cascade for endothelial cells. Arterioscler Thromb Vasc Biol (2000) 1.50
Effect of statin therapy on restenosis after coronary stent implantation. Am J Cardiol (2000) 1.50
Holt-Oram syndrome. Circulation (1999) 1.49
Calcium handling proteins in the failing human heart. Basic Res Cardiol (1997) 1.48
Ubiquitin-mediated degradation of the proapoptotic active form of bid. A functional consequence on apoptosis induction. J Biol Chem (2000) 1.45
Nitric oxide inhibits dystrophin proteolysis by coxsackieviral protease 2A through S-nitrosylation: A protective mechanism against enteroviral cardiomyopathy. Circulation (2000) 1.44
Aging enhances the sensitivity of endothelial cells toward apoptotic stimuli: important role of nitric oxide. Circ Res (2001) 1.44
Interventional cardiology in Europe 1994. Working Group Coronary Circulation of the European Society of Cardiology. Eur Heart J (1998) 1.44
Chiari's network: normal anatomic variant or risk factor for arterial embolic events? J Am Coll Cardiol (1995) 1.43
Reduced plasma L-arginine in hypercholesterolaemia. Lancet (1992) 1.42
Membrane-covered stents: a new treatment strategy for saphenous vein graft lesions. Catheter Cardiovasc Interv (2001) 1.42
Statin therapy is associated with reduced restenosis rates after coronary stent implantation in carriers of the Pl(A2)allele of the platelet glycoprotein IIIa gene. Eur Heart J (2001) 1.42
Antibodies to chlamydial lipopolysaccharides in unstable angina pectoris. Am J Cardiol (2001) 1.42
Vitamin C improves endothelial function of epicardial coronary arteries in patients with hypercholesterolaemia or essential hypertension--assessed by cold pressor testing. Eur Heart J (1999) 1.42
Deformation of coronary stents by cardiopulmonary resuscitation. J Invasive Cardiol (1999) 1.41
Angiotensin II induces apoptosis of human endothelial cells. Protective effect of nitric oxide. Circ Res (1997) 1.41
Scoring system for nosocomial pneumonia in ICUs. Intensive Care Med (1996) 1.41
Continuous arteriovenous haemoperfusion (CAVHP) for treatment of paraquat poisoning. Nephrol Dial Transplant (1992) 1.41
Long-term antiarrhythmic therapy with flecainide. Am J Cardiol (1984) 1.39
Protection of side-branches in coronary lesions with a new stent design. Cathet Cardiovasc Diagn (1998) 1.39
Prevalence of circadian variations and spontaneous variability of cardiac disorders and ECG changes suggestive of myocardial ischemia in systemic arterial hypertension. Circulation (1992) 1.39
[Diagnostic value of various echo- and Doppler echocardiography methods in quantifying mitral valve stenosis]. Z Kardiol (1996) 1.39
[The effect of a lower stimulation frequency on the AV synchronicity of VDD pacemakers]. Dtsch Med Wochenschr (1997) 1.38
[A 73-year-old patient with hypertensive crisis. Was the use of calcium antagonist nifedipine justified?]. Internist (Berl) (1999) 1.38
[Angina pectoris in normal coronary arteries (microvascular angina/syndrome X)]. Dtsch Med Wochenschr (1997) 1.38
Interventional cardiology in Europe 1995. Working Group Coronary Circulation of the European Society of Cardiology. Eur Heart J (1999) 1.36
Apoptosis of endothelial cells. Contribution to the pathophysiology of atherosclerosis? Eur Cytokine Netw (1998) 1.35
Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients. Circulation (1997) 1.34
Nitric oxide and apoptosis: another paradigm for the double-edged role of nitric oxide. Nitric Oxide (1997) 1.33
Upregulation of superoxide dismutase and nitric oxide synthase mediates the apoptosis-suppressive effects of shear stress on endothelial cells. Arterioscler Thromb Vasc Biol (1999) 1.31
Oxidized low-density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32-like proteases. A mechanistic clue to the 'response to injury' hypothesis. Circulation (1997) 1.31
Nitric oxide activates telomerase and delays endothelial cell senescence. Circ Res (2000) 1.29
Cardiovascular risk factors in primary care: methods and baseline prevalence rates--the DETECT program. Curr Med Res Opin (2005) 1.29
Improved morphologic characterization of atrial septal aneurysm by transesophageal echocardiography: relation to cerebrovascular events. J Am Coll Cardiol (1990) 1.29
"Real life" use of sirolimus-eluting coronary stents in Germany. Results from the prospective multi-centre German Cypher Registry. Z Kardiol (2004) 1.28
Allele-specific regulation of matrix metalloproteinase-7 promoter activity is associated with coronary artery luminal dimensions among hypercholesterolemic patients. Arterioscler Thromb Vasc Biol (2001) 1.28
Effects of long-term nitroglycerin treatment on endothelial nitric oxide synthase (NOS III) gene expression, NOS III-mediated superoxide production, and vascular NO bioavailability. Circ Res (2000) 1.27
Impact of long-term ECG recording on the detection of paroxysmal atrial fibrillation in patients after an acute ischemic stroke. Pacing Clin Electrophysiol (1999) 1.26
Shear stress inhibits H2O2-induced apoptosis of human endothelial cells by modulation of the glutathione redox cycle and nitric oxide synthase. Arterioscler Thromb Vasc Biol (1997) 1.26
Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: evidence for an involvement of protein kinase C. Kidney Int (1999) 1.25