Published in J Invest Dermatol on September 01, 1989
Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase. EMBO J (2003) 1.31
Erythropoietic and hepatic porphyrias. J Inherit Metab Dis (2000) 1.00
Angiosarcoma, porphyria cutanea tarda, and probable chloracne in a worker exposed to waste oil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Br J Ind Med (1993) 0.76
Incidence of hereditary porphyria cutanea tarda (PCT) in a sample of the Italian population. Arch Dermatol Res (1992) 0.75
Diagnosis of pseudomembranous colitis. Br Med J (1978) 5.96
Effects by heme, insulin, and serum albumin on heme and protein synthesis in chick embryo liver cells cultured in a chemically defined medium, and a spectrofluorometric assay for porphyrin composition. J Biol Chem (1975) 2.47
Cobalt induction of hepatic heme oxygenase; with evidence that cytochrome P-450 is not essential for this enzyme activity. Proc Natl Acad Sci U S A (1974) 2.41
Sequential induction of heme pathway enzymes during erythroid differentiation of mouse Friend leukemia virus-infected cells. J Exp Med (1976) 2.36
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1. EMBO J (2001) 2.32
Suppression of bilirubin production in the Crigler-Najjar type I syndrome: studies with the heme oxygenase inhibitor tin-mesoporphyrin. Pediatrics (1992) 2.14
Cobalt stimulation of heme degradation in the liver. Dissociation of microsomal oxidation of heme from cytochrome P-450. J Biol Chem (1975) 2.05
Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation. Proc Natl Acad Sci U S A (1981) 2.04
Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia. Nat Genet (1998) 1.98
Plasma membranes of the rat liver. Isolation and enzymatic characterization of a fraction rich in bile canaliculi. J Cell Biol (1969) 1.95
Steroid induction of porphyrin synthesis in liver cell culture. I. Structural basis and possible physiological role in the control of heme formation. J Biol Chem (1967) 1.93
Influence of dietary protein and carbohydrate on antipyrine and theophylline metabolism in man. Clin Pharmacol Ther (1976) 1.87
Metals as regulators of heme metabolism. Science (1977) 1.86
Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene. Proc Natl Acad Sci U S A (1994) 1.85
Studies on the mechanism of induction of haem oxygenase by cobalt and other metal ions. Biochem J (1976) 1.84
Induction of aminolevulinate synthase and porphyrins in cultured liver cells maintained in chemically defined medium. Permissive effects of hormones on induction process. J Biol Chem (1977) 1.83
Purification and properties of bovine spleen heme oxygenase. Amino acid composition and sites of action of inhibitors of heme oxidation. J Biol Chem (1982) 1.83
Induction of -aminolevulinic acid synthetase in chick embryo liver cells in cluture. Proc Natl Acad Sci U S A (1970) 1.77
Assays for porphyrins, delta-aminolevulinic-acid dehydratase, and porphyrinogen synthetase in microliter samples of whole blood: applications to metabolic defects involving the heme pathway. Proc Natl Acad Sci U S A (1972) 1.77
Steroid induction of porphyrin synthesis in liver cell culture. II. The effects of heme, uridine diphosphate glucuronic acid, and inhibitors of nucleic acid and protein synthesis on the induction process. J Biol Chem (1968) 1.76
Circulating endothelial cells are elevated in patients with type 2 diabetes mellitus independently of HbA(1)c. Diabetologia (2005) 1.69
Prevention of cyclical attacks of acute intermittent porphyria with a long-acting agonist of luteinizing hormone-releasing hormone. N Engl J Med (1984) 1.68
The influence of pregnancy and oral contraceptive steroids on the concentration of plasma proteins. Studies with a quantitative immunodiffusion method. Am J Obstet Gynecol (1970) 1.65
Porphyria cutanea tarda. Clinical features and laboratory findings in 40 patients. Am J Med (1979) 1.65
A zebrafish model for hepatoerythropoietic porphyria. Nat Genet (1998) 1.62
Deficiency of acylpeptide hydrolase in small-cell lung carcinoma cell lines. J Lab Clin Med (1992) 1.58
Porphyria cutanea tarda associated with the acquired immune deficiency syndrome. Am J Hematol (1987) 1.57
Studies in lead poisoning. I. Microanalysis of erythrocyte protoporphyrin levels by spectrophotometry in the detection of chronic lead intoxication in the subclinical range. Biochem Med (1973) 1.53
Lead binding to delta-aminolevulinic acid dehydratase (ALAD) in human erythrocytes. Pharmacol Toxicol (1997) 1.50
Purification and properties of uroporphyrinogen decarboxylase from human erythrocytes. A single enzyme catalyzing the four sequential decarboxylations of uroporphyrinogens I and III. J Biol Chem (1983) 1.50
Delta-aminolevulinic acid dehydratase assay. Enzyme (1982) 1.49
Polychlorinated biphenyls: a new type of inducer of cytochrome P-448 in the liver. Proc Natl Acad Sci U S A (1973) 1.48
A microassay for uroporphyrinogen I synthase, one of three abnormal enzyme activities in acute intermittent porphyria, and its application to the study of the genetics of this disease. Proc Natl Acad Sci U S A (1974) 1.48
Human heme oxygenase-1 gene transfer lowers blood pressure and promotes growth in spontaneously hypertensive rats. Hypertension (2001) 1.48
Interactions between nutritional factors and drug biotransformations in man. Proc Natl Acad Sci U S A (1976) 1.47
Control of hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns using an inhibitor of bilirubin production, Sn-mesoporphyrin. Pediatrics (1998) 1.44
Operative choledochoscopy. Br J Surg (1979) 1.43
Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity. Proc Natl Acad Sci U S A (1995) 1.41
Stimulation of hemoglobin synthesis in chick blastoderms by certain 5beta androstane and 5beta pregnane steroids. Proc Natl Acad Sci U S A (1967) 1.41
Steroid control of porphyrin and heme biosynthesis: a new biological function of steroid hormone metabolites. Proc Natl Acad Sci U S A (1967) 1.41
Erythropoietic protoporphyria. 10 years experience. Am J Med (1976) 1.39
Induction of aryl hydrocarbon hydroxylase in human skin. Drug Metab Dispos (1974) 1.39
Heme biosynthesis and drug metabolism in mice with hereditary hemolytic anemia. Heme oxygenase induction as an adaptive response for maintaining cytochrome P-450 in chronic hemolysis. J Biol Chem (1979) 1.39
Stimulatory effect of brussels sprouts and cabbage on human drug metabolism. Clin Pharmacol Ther (1979) 1.38
Alterations in drug metabolism in workers exposed to polychlorinated biphenyls. Clin Pharmacol Ther (1977) 1.38
Heme oxygenase-1: a novel therapeutic target in oxidative tissue injuries. Curr Med Chem (2004) 1.36
Chemoprevention of neonatal jaundice: potency of tin-protoporphyrin in an animal model. Science (1982) 1.36
Lead and methyl mercury: effects of acute exposure on cytochrome P-450 and the mixed function oxidase system in the liver. J Exp Med (1972) 1.35
Studies of the influence of chloro-substituent sites and conformational energy in polychlorinated biphenyls on uroporphyrin formation in chick-embryo liver cell cultures. Biochem J (1986) 1.35
Biologic actions of some natural steroids on the liver. N Engl J Med (1968) 1.34
Dual control mechanism for heme oxygenase: tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liver. Proc Natl Acad Sci U S A (1987) 1.31
Erythropoietic protoporphyria: lipid peroxidation and red cell membrane damage associated with photohemolysis. J Clin Invest (1972) 1.27
Tin: a potent inducer of heme oxygenase in kidney. Science (1976) 1.27
Control of heme oxygenase and plasma levels of bilirubin by a synthetic heme analogue, tin-protoporphyrin. Hepatology (1984) 1.26
On the genetic activity of benzimidazole and thiophanate fungicides on diploid Aspergillus nidulans. Mutat Res (1974) 1.25
Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7. Blood (1993) 1.25
Effect of lead and genetic factors on heme biosynthesis in the human red cell. Ann N Y Acad Sci (1975) 1.24
Tissue distribution and disposition of tin-protoporphyrin, a potent competitive inhibitor of heme oxygenase. J Pharmacol Exp Ther (1984) 1.24
Contingency detection and the contingent organization of behavior in interactions: implications for socioemotional development in infancy. Psychol Bull (1996) 1.24
Control of heme metabolism with synthetic metalloporphyrins. J Clin Invest (1986) 1.23
Hereditary tyrosinemia and the heme biosynthetic pathway. Profound inhibition of delta-aminolevulinic acid dehydratase activity by succinylacetone. J Clin Invest (1983) 1.22
Heme biosynthesis in bacterium-protozoon symbioses: enzymic defects in host hemoflagellates and complemental role of their intracellular symbiotes. Proc Natl Acad Sci U S A (1975) 1.22
Biochemical studies of a patient with hereditary hepatorenal tyrosinemia: evidence of glutathione deficiency. Pediatr Res (1984) 1.20
Beta-carotene as a photoprotective agent in erythropoietic protoporphyria. N Engl J Med (1970) 1.19
Solubilization and partial purification of heme oxygenase from rat liver. J Biol Chem (1977) 1.19
Studies in lead poisoning. II. Correlation between the ratio of activated to inactivated delta-aminolevulinic acid dehydratase of whole blood and the blood lead level. Biochem Med (1973) 1.19
Prematurely evoked synthesis and induction of delta-aminolevulinate synthetase in neonatal liver. Evidence for metal ion repression of enzyme formation. J Biol Chem (1978) 1.19
Cobalt inhibition of synthesis and induction of delta-aminolevulinate synthase in liver. Proc Natl Acad Sci U S A (1976) 1.18
Regulation of heme pathway enzymes and cellular glutathione content by metals that do not chelate with tetrapyrroles: blockade of metal effects by thiols. Proc Natl Acad Sci U S A (1977) 1.18
Tumor promoter-mediated inhibition of cell differentiation: suppression of the expression of erythroid functions in murine erythroleukemia cells. Proc Natl Acad Sci U S A (1979) 1.18
Stimulation of mammalian erythropoiesis by 5beta-H steroid metabolites. Proc Natl Acad Sci U S A (1970) 1.17
Hormones and the liver. The effect of estrogens, progestins, and pregnancy on hepatic function. Am J Obstet Gynecol (1969) 1.16
Regulation of NF-E2 activity in erythroleukemia cell differentiation. J Biol Chem (1998) 1.15
Tin-protoporphyrin suppression of hyperbilirubinemia in mutant mice with severe hemolytic anemia. Blood (1983) 1.15
Effects of polychlorinated biphenyl compounds, 2,3,7,8-tetrachlorodibenzo-p-dioxin, phenobarbital and iron on hepatic uroporphyrinogen decarboxylase. Implications for the pathogenesis of porphyria. Biochem J (1983) 1.15
Studies in porphyria. IV. Expression of the gene defect of acute intermittent porphyria in cultured human skin fibroblasts and amniotic cells: prenatal diagnosis of the porphyric trait. J Exp Med (1975) 1.14
Reduction of the C2 and C4 vinyl groups of Sn-protoporphyrin to form Sn-mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolism. Arch Biochem Biophys (1987) 1.14
Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload. EMBO J (1999) 1.14
Molecular aspects of the inherited porphyrias. J Intern Med (2000) 1.13
Additive effect of erythropoietin and heme on murine hematopoietic recovery after azidothymidine treatment. Blood (1993) 1.13
Hyperbeta-lipoproteinemia in acute intermittent porphyria; preliminary report. N Engl J Med (1970) 1.12
Drug metabolism in normal children, lead-poisoned children, and normal adults. Clin Pharmacol Ther (1975) 1.12
Study of the developmental pattern of heme catabolism in liver and the effects of cobalt on cytochrome P-450 and the rate of heme oxidation during the neonatal period. J Exp Med (1975) 1.12