The Neurobiological Basis for Social Affiliation in Autism Spectrum Disorder and Schizophrenia.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27695666)

Published in Curr Behav Neurosci Rep on April 16, 2016

Authors

Amanda Crider1, Anilkumar Pillai1

Author Affiliations

1: Department of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, GA 30912.

Articles cited by this

(truncated to the top 100)

Structural variation of chromosomes in autism spectrum disorder. Am J Hum Genet (2008) 15.51

Functional impact of global rare copy number variation in autism spectrum disorders. Nature (2010) 14.66

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders. Nat Genet (2006) 11.14

Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism. Neuron (2011) 10.61

MeCP2, a key contributor to neurological disease, activates and represses transcription. Science (2008) 10.11

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet (2001) 9.82

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat Genet (2001) 8.64

Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell (2013) 8.11

Copy-number variations associated with neuropsychiatric conditions. Nature (2008) 6.78

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. Nature (2011) 5.62

Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study. Arch Gen Psychiatry (2000) 5.12

Schizophrenia: a concise overview of incidence, prevalence, and mortality. Epidemiol Rev (2008) 4.43

Sex differences in the brain: implications for explaining autism. Science (2005) 4.38

Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation. Nat Genet (2010) 3.73

A decrease of reelin expression as a putative vulnerability factor in schizophrenia. Proc Natl Acad Sci U S A (1998) 3.33

De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Proc Natl Acad Sci U S A (2010) 3.13

Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. Nature (2012) 2.99

Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons. J Neurosci (2005) 2.96

Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population. Biol Psychiatry (2005) 2.79

Plasma oxytocin levels in autistic children. Biol Psychiatry (1998) 2.77

ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease. J Neurochem (2002) 2.71

Deletion 17q12 is a recurrent copy number variant that confers high risk of autism and schizophrenia. Am J Hum Genet (2010) 2.70

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior. Nat Neurosci (2014) 2.69

Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse. J Neurosci (1998) 2.48

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication. Mol Autism (2010) 2.47

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature (2012) 2.36

Gaze behavior and affect at 6 months: predicting clinical outcomes and language development in typically developing infants and infants at risk for autism. Dev Sci (2009) 2.35

Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report. Am J Med Genet B Neuropsychiatr Genet (2005) 2.34

Autism spectrum disorders--a genetics review. Genet Med (2011) 2.29

Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2. Proc Natl Acad Sci U S A (2007) 2.27

Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1. J Neurosci (2008) 2.27

Reelin is preferentially expressed in neurons synthesizing gamma-aminobutyric acid in cortex and hippocampus of adult rats. Proc Natl Acad Sci U S A (1998) 2.18

Reelin gene alleles and susceptibility to autism spectrum disorders. Mol Psychiatry (2002) 2.05

Characterization of the Shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development. J Biol Chem (1999) 2.03

Specific genetic disorders and autism: clinical contribution towards their identification. J Autism Dev Disord (2005) 2.03

Genes controlling affiliative behavior as candidate genes for autism. Biol Psychiatry (2008) 2.00

Variation in the oxytocin receptor gene is associated with pair-bonding and social behavior. Biol Psychiatry (2011) 1.89

The genetic landscapes of autism spectrum disorders. Annu Rev Genomics Hum Genet (2013) 1.77

The Reelin signaling pathway promotes dendritic spine development in hippocampal neurons. J Neurosci (2008) 1.75

Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice. Biol Psychiatry (2005) 1.74

Toxoplasma infection and later development of schizophrenia in mothers. Am J Psychiatry (2011) 1.69

GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and Reelin proteins in cerebellum. Schizophr Res (2005) 1.67

Modeling autism by SHANK gene mutations in mice. Neuron (2013) 1.64

De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability. Mol Psychiatry (2014) 1.62

Oxytocin enhances brain function in children with autism. Proc Natl Acad Sci U S A (2013) 1.61

Sociability and motor functions in Shank1 mutant mice. Brain Res (2010) 1.60

SHANK1 Deletions in Males with Autism Spectrum Disorder. Am J Hum Genet (2012) 1.59

A sexually dimorphic hypothalamic circuit controls maternal care and oxytocin secretion. Nature (2015) 1.58

Microglial activation in young adults with autism spectrum disorder. JAMA Psychiatry (2013) 1.57

Autistic disturbances of affective contact. Acta Paedopsychiatr (1968) 1.51

MECP2 structural and 3'-UTR variants in schizophrenia, autism and other psychiatric diseases: a possible association with autism. Am J Med Genet B Neuropsychiatr Genet (2004) 1.51

Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder. Nat Genet (2003) 1.46

Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2. Neuron (2016) 1.45

Genetics of schizophrenia: new findings and challenges. Annu Rev Genomics Hum Genet (2011) 1.41

Communication impairments in mice lacking Shank1: reduced levels of ultrasonic vocalizations and scent marking behavior. PLoS One (2011) 1.40

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies. Trends Cell Biol (2011) 1.38

Schizophrenia. BMJ (2007) 1.37

Rare structural variation of synapse and neurotransmission genes in autism. Mol Psychiatry (2011) 1.36

Genetic and non-genetic vulnerability factors in schizophrenia: the basis of the "two hit hypothesis". J Psychiatr Res (2000) 1.34

Neural development, cell-cell signaling, and the "two-hit" hypothesis of schizophrenia. Schizophr Bull (2001) 1.34

Diminished plasma oxytocin in schizophrenic patients with neuroendocrine dysfunction and emotional deficits. Schizophr Res (2007) 1.32

Effects of oxytocin on recollections of maternal care and closeness. Proc Natl Acad Sci U S A (2010) 1.30

Evidence for the involvement of genetic variation in the oxytocin receptor gene (OXTR) in the etiology of autistic disorders on high-functioning level. Am J Med Genet B Neuropsychiatr Genet (2010) 1.30

Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism. Nat Commun (2014) 1.25

Anxiety, social deficits, and loneliness in youth with autism spectrum disorders. J Autism Dev Disord (2009) 1.24

The role of oxytocin in psychiatric disorders: a review of biological and therapeutic research findings. Harv Rev Psychiatry (2014) 1.18

Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia. Biol Psychiatry (1993) 1.18

Video-based quantification of body movement during social interaction indicates the severity of negative symptoms in patients with schizophrenia. Schizophr Res (2010) 1.13

Enhancement of inhibitory neurotransmission by GABAA receptors having α2,3-subunits ameliorates behavioral deficits in a mouse model of autism. Neuron (2014) 1.12

The effect of oxytocin nasal spray on social interaction deficits observed in young children with autism: a randomized clinical crossover trial. Mol Psychiatry (2015) 1.11

Altered cortical expression of GABA-related genes in schizophrenia: illness progression vs developmental disturbance. Schizophr Bull (2013) 1.09

DNA methylation of the oxytocin receptor gene predicts neural response to ambiguous social stimuli. Front Hum Neurosci (2012) 1.08

Molecular characterisation of gastrointestinal microbiota of children with autism (with and without gastrointestinal dysfunction) and their neurotypical siblings. Autism Res (2012) 1.08

Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain. Neuroscience (2011) 1.07

Alternatively activated myeloid (M2) cells enhance cognitive function in immune compromised mice. Brain Behav Immun (2010) 1.05

Immune system gene dysregulation in autism and schizophrenia. Dev Neurobiol (2012) 1.04

Estradiol for treatment-resistant schizophrenia: a large-scale randomized-controlled trial in women of child-bearing age. Mol Psychiatry (2014) 1.03

Mitigation of sociocommunicational deficits of autism through oxytocin-induced recovery of medial prefrontal activity: a randomized trial. JAMA Psychiatry (2014) 1.02

The association analysis of RELN and GRM8 genes with autistic spectrum disorder in Chinese Han population. Am J Med Genet B Neuropsychiatr Genet (2008) 1.01

Role for Reelin in neurotransmitter release. J Neurosci (2011) 1.01

An environmental analysis of genes associated with schizophrenia: hypoxia and vascular factors as interacting elements in the neurodevelopmental model. Mol Psychiatry (2012) 1.00

Vasopressin--oxytocin in cerebrospinal fluid of schizophrenic patients and normal controls. Psychoneuroendocrinology (1985) 1.00

Autism spectrum disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1. Cell Death Dis (2010) 0.99

Inflammation and the two-hit hypothesis of schizophrenia. Neurosci Biobehav Rev (2013) 0.98

Oxytocin increases eye contact during a real-time, naturalistic social interaction in males with and without autism. Transl Psychiatry (2015) 0.97

GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism. Neuropsychopharmacology (2015) 0.97

Bilirubin increases insulin sensitivity in leptin-receptor deficient and diet-induced obese mice through suppression of ER stress and chronic inflammation. Endocrinology (2014) 0.94

Early markers of autism spectrum disorders in infants and toddlers prospectively identified in the Social Attention and Communication Study. Autism (2012) 0.94

Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects. Neuron (2015) 0.94

Oxytocin administration enhances controlled social cognition in patients with schizophrenia. Psychoneuroendocrinology (2014) 0.93

A pilot six-week randomized controlled trial of oxytocin on social cognition and social skills in schizophrenia. Schizophr Res (2014) 0.93

Oxytocin in schizophrenia: a review of evidence for its therapeutic effects. Acta Neuropsychiatr (2011) 0.93

Prenatal stress induces schizophrenia-like alterations of serotonin 2A and metabotropic glutamate 2 receptors in the adult offspring: role of maternal immune system. J Neurosci (2013) 0.92

Cerebrospinal fluid oxytocin concentration in schizophrenic patients does not differ from control subjects and is not changed by neuroleptic medication. Schizophr Res (1994) 0.90

Reelin gene variants and risk of autism spectrum disorders: an integrated meta-analysis. Am J Med Genet B Neuropsychiatr Genet (2014) 0.90

Oxytocin and oxytocin receptor gene polymorphisms and risk for schizophrenia: a case-control study. World J Biol Psychiatry (2012) 0.89

Frontal Glutamate and γ-Aminobutyric Acid Levels and Their Associations With Mismatch Negativity and Digit Sequencing Task Performance in Schizophrenia. JAMA Psychiatry (2016) 0.89

Social cognition and quality of life in schizophrenia. Schizophr Res (2012) 0.88

Prior exposure To oxytocin mimics the effects Of social contact and facilitates sexual behaviour In females. J Neuroendocrinol (1999) 0.87

Social competence versus negative symptoms as predictors of real world social functioning in schizophrenia. Schizophr Res (2014) 0.87