Promoter methylation and downregulated expression of the TBX15 gene in ovarian carcinoma.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27698863)

Published in Oncol Lett on August 16, 2016

Authors

Gaia Gozzi1, Sonia T Chelbi2, Paola Manni3, Loredana Alberti4, Sergio Fonda3, Sara Saponaro1, Luca Fabbiani5, Francesco Rivasi5, Jean Benhattar6, Lorena Losi3

Author Affiliations

1: Pathological Anatomy Unit, Department of Life Sciences, University of Modena and Reggio Emilia, I-41124 Modena, Italy; University Institute of Pathology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
2: University Institute of Pathology, Lausanne University Hospital, 1011 Lausanne, Switzerland; Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland.
3: Pathological Anatomy Unit, Department of Life Sciences, University of Modena and Reggio Emilia, I-41124 Modena, Italy.
4: University Institute of Pathology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
5: Department of Diagnostic Medicine, Clinic and Public Health, University of Modena and Reggio Emilia, I-41124 Modena, Italy.
6: University Institute of Pathology, Lausanne University Hospital, 1011 Lausanne, Switzerland; Biopath Lab, Medical Biology and Pathology, 1006 Lausanne, Switzerland.

Articles cited by this

The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell (2008) 46.08

The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory. Am J Surg Pathol (2010) 7.27

BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing. Bioinformatics (2005) 5.95

Grading ovarian serous carcinoma using a two-tier system. Am J Surg Pathol (2004) 3.49

Staging classification for cancer of the ovary, fallopian tube, and peritoneum. Int J Gynaecol Obstet (2013) 2.82

T-box genes in early embryogenesis. Dev Dyn (2004) 2.45

Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer. J Mammary Gland Biol Neoplasia (2010) 2.38

Histopathologic grading of ovarian carcinoma: a review and proposal. Int J Gynecol Pathol (2000) 1.83

The 'Marx' of Groucho on development and disease. Trends Cell Biol (2007) 1.73

T-bet, a T-cell-associated transcription factor, is expressed in a subset of B-cell lymphoproliferative disorders. Am J Clin Pathol (2004) 1.70

T-bet, a T cell-associated transcription factor, is expressed in Hodgkin's lymphoma. Hum Pathol (2005) 1.52

Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta. Genes Dev (1994) 1.46

Evolution of intratumoral genetic heterogeneity during colorectal cancer progression. Carcinogenesis (2005) 1.45

Intertumor and intratumor NY-ESO-1 expression heterogeneity is associated with promoter-specific and global DNA methylation status in ovarian cancer. Clin Cancer Res (2008) 1.32

The role of Tbx2 and Tbx3 in mammary development and tumorigenesis. J Mammary Gland Biol Neoplasia (2004) 1.31

Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors. J Biol Chem (2007) 1.31

Ovarian surface epithelium as a source of ovarian cancers: unwarranted speculation or evidence-based hypothesis? Gynecol Oncol (2013) 1.29

Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays. PLoS One (2009) 1.28

Expression of the Brachyury gene during mesoderm development in differentiating embryonal carcinoma cell cultures. Development (1994) 1.17

BRACHYURY confers cancer stem cell characteristics on colorectal cancer cells. Int J Cancer (2011) 1.08

T-box transcription factor Brachyury expression is correlated with epithelial-mesenchymal transition and lymph node metastasis in oral squamous cell carcinoma. Int J Oncol (2012) 1.02

Tbx3 expression is related to apoptosis and cell proliferation in rat bladder both hyperplastic epithelial cells and carcinoma cells. Cancer Lett (2005) 1.00

Correlation of ERG expression and DNA methylation biomarkers with adverse clinicopathologic features of prostate cancer. Clin Cancer Res (2012) 0.98

Regulation of organogenesis and stem cell properties by T-box transcription factors. Cell Mol Life Sci (2013) 0.88

Epigenetic biomarkers in epithelial ovarian cancer. Cancer Lett (2012) 0.87

Clonal intratumor heterogeneity of promoter hypermethylation in breast cancer by MS-MLPA. Mod Pathol (2013) 0.87

Combination of promoter hypomethylation and PDX1 overexpression leads to TBX15 decrease in vascular IUGR placentas. Epigenetics (2011) 0.86