Published in J Biol Chem on June 21, 2007
TBX15 mutations cause craniofacial dysmorphism, hypoplasia of scapula and pelvis, and short stature in Cousin syndrome. Am J Hum Genet (2008) 1.68
Vascular smooth muscle progenitor cells: building and repairing blood vessels. Circ Res (2011) 1.46
Mesodermal developmental gene Tbx15 impairs adipocyte differentiation and mitochondrial respiration. Proc Natl Acad Sci U S A (2011) 1.14
Teasing out T-box targets in early mesoderm. Curr Opin Genet Dev (2008) 1.13
Tbx18 targets dermal condensates for labeling, isolation, and gene ablation during embryonic hair follicle formation. J Invest Dermatol (2012) 1.13
Ash2l interacts with Tbx1 and is required during early embryogenesis. Exp Biol Med (Maywood) (2010) 1.06
Intrinsic sex differences in the early growth hormone responsiveness of sex-specific genes in mouse liver. Mol Endocrinol (2010) 1.05
Transcriptional suppression of connexin43 by TBX18 undermines cell-cell electrical coupling in postnatal cardiomyocytes. J Biol Chem (2011) 1.04
Expression of the oscillating gene her1 is directly regulated by Hairy/Enhancer of Split, T-box, and Suppressor of Hairless proteins in the zebrafish segmentation clock. Dev Dyn (2009) 0.96
Expression of somite segmentation genes in amphioxus: a clock without a wavefront? Dev Genes Evol (2008) 0.93
De novo TBR1 mutations in sporadic autism disrupt protein functions. Nat Commun (2014) 0.92
Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton. Dev Biol (2009) 0.92
Tbx18 regulates development of the epicardium and coronary vessels. Dev Biol (2013) 0.87
Function of the C. elegans T-box factor TBX-2 depends on SUMOylation. Cell Mol Life Sci (2013) 0.84
Mutations in TBX18 Cause Dominant Urinary Tract Malformations via Transcriptional Dysregulation of Ureter Development. Am J Hum Genet (2015) 0.83
Mammalian TBX1 preferentially binds and regulates downstream targets via a tandem T-site repeat. PLoS One (2014) 0.82
Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity. PLoS One (2011) 0.81
A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression. J Proteome Res (2013) 0.81
From dynamic expression patterns to boundary formation in the presomitic mesoderm. PLoS Comput Biol (2012) 0.81
Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism. Nat Commun (2015) 0.80
Novel mutations in the transcriptional activator domain of the human TBX20 in patients with atrial septal defect. Biomed Res Int (2015) 0.79
Human breast progenitor cell numbers are regulated by WNT and TBX3. PLoS One (2014) 0.78
The Caenorhabditis elegans T-box factor MLS-1 requires Groucho co-repressor interaction for uterine muscle specification. PLoS Genet (2011) 0.78
In vitro site selection of a consensus binding site for the Drosophila melanogaster Tbx20 homolog midline. PLoS One (2012) 0.77
Prediction of functional engrailed homology-1 protein motif from sequence. Bioinformation (2009) 0.76
Ezh2 restricts the smooth muscle lineage during mouse lung mesothelial development. Development (2016) 0.76
Teed off: cardiac conduction system development requires T-box transcription factors. Circ Res (2008) 0.75
Lack of Genetic Interaction between Tbx18 and Tbx2/Tbx20 in Mouse Epicardial Development. PLoS One (2016) 0.75
Transcriptional Control of Cell Lineage Development in Epicardium-Derived Cells. J Dev Biol (2013) 0.75
Promoter methylation and downregulated expression of the TBX15 gene in ovarian carcinoma. Oncol Lett (2016) 0.75
Function of the C. elegans T-box factor TBX-2 depends on interaction with the UNC-37/Groucho corepressor. Dev Biol (2016) 0.75
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature (2008) 10.73
The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nat Genet (2006) 5.36
Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible. Nat Genet (2006) 5.29
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. Nat Genet (2003) 5.24
Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry. Nat Genet (2002) 4.64
Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis. Nat Genet (2003) 4.14
Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1. J Biol Chem (2003) 3.68
Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin. Nat Genet (2005) 3.55
Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Development (2003) 3.08
Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia. Am J Hum Genet (2008) 2.74
Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development (2007) 2.70
Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation. Hum Mol Genet (2004) 2.63
Tbx18 and the fate of epicardial progenitors. Nature (2009) 2.42
Semaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1. Dev Cell (2011) 2.23
COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J Clin Invest (2011) 2.21
Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. J Exp Med (2008) 2.17
CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs. Nat Genet (2010) 2.12
Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects. Am J Hum Genet (2009) 2.10
Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells. Dev Cell (2012) 2.06
Okihiro syndrome is caused by SALL4 mutations. Hum Mol Genet (2002) 2.06
The Tbx2+ primary myocardium of the atrioventricular canal forms the atrioventricular node and the base of the left ventricle. Circ Res (2009) 2.02
Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3. Circ Res (2008) 1.90
AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis. Nat Genet (2010) 1.89
Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay. Development (2005) 1.85
Tbx3 promotes liver bud expansion during mouse development by suppression of cholangiocyte differentiation. Hepatology (2009) 1.80
Cystin localizes to primary cilia via membrane microdomains and a targeting motif. J Am Soc Nephrol (2009) 1.79
Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction. Nat Cell Biol (2008) 1.76
WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos. Genes Dev (2004) 1.74
Formation of the venous pole of the heart from an Nkx2-5-negative precursor population requires Tbx18. Circ Res (2006) 1.70
TBX15 mutations cause craniofacial dysmorphism, hypoplasia of scapula and pelvis, and short stature in Cousin syndrome. Am J Hum Genet (2008) 1.68
Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies. Cell Stem Cell (2011) 1.67
Tbx18 regulates the development of the ureteral mesenchyme. J Clin Invest (2006) 1.63
Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2. Development (2005) 1.61
Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos. Blood (2012) 1.56
The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev (2004) 1.46
Development of the pacemaker tissues of the heart. Circ Res (2010) 1.46
Epicardial function of canonical Wnt-, Hedgehog-, Fgfr1/2-, and Pdgfra-signalling. Cardiovasc Res (2013) 1.45
Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis. Dev Biol (2007) 1.40
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo. J Cell Biol (2007) 1.39
The T-box transcription factor Tbx15 is required for skeletal development. Mech Dev (2005) 1.35
Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res (2011) 1.34
Mechanisms of T-box gene function in the developing heart. Cardiovasc Res (2011) 1.33
Transcriptional oscillation of lunatic fringe is essential for somitogenesis. Genes Dev (2003) 1.29
Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects. Dev Biol (2008) 1.29
An interacting network of T-box genes directs gene expression and fate in the zebrafish mesoderm. Proc Natl Acad Sci U S A (2003) 1.28
Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5. J Biol Chem (2006) 1.27
Developmental origin, growth, and three-dimensional architecture of the atrioventricular conduction axis of the mouse heart. Circ Res (2010) 1.24
TBX22 missense mutations found in patients with X-linked cleft palate affect DNA binding, sumoylation, and transcriptional repression. Am J Hum Genet (2007) 1.23
Tbx20 interacts with smads to confine tbx2 expression to the atrioventricular canal. Circ Res (2009) 1.21
Wt1 and epicardial fate mapping. Circ Res (2012) 1.19
Cardiac conduction is required to preserve cardiac chamber morphology. Proc Natl Acad Sci U S A (2010) 1.17
The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation. Genes Dev (2004) 1.17
Expression of Msgn1 in the presomitic mesoderm is controlled by synergism of WNT signalling and Tbx6. EMBO Rep (2007) 1.17
The prepattern transcription factor Irx3 directs nephron segment identity. Genes Dev (2007) 1.16
Analysis of TBX18 expression in chick embryos. Dev Genes Evol (2004) 1.13
Deafness in mice lacking the T-box transcription factor Tbx18 in otic fibrocytes. Development (2008) 1.13
WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn (2008) 1.11
Imprinted gene dosage is critical for the transition to independent life. Cell Metab (2012) 1.10
Sox9 is required for notochord maintenance in mice. Dev Biol (2006) 1.09
Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart. Dev Biol (2006) 1.08
Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients. Am J Respir Cell Mol Biol (2005) 1.08
Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation. Genes Dev (2008) 1.06
Specification of vertebral identity is coupled to Notch signalling and the segmentation clock. Development (2004) 1.05
Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis. J Comp Neurol (2006) 1.05
Distinct enhancers at the Pax3 locus can function redundantly to regulate neural tube and neural crest expressions. Dev Biol (2010) 1.03
Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons. Dev Biol (2006) 1.00
Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme. Hum Mol Genet (2010) 0.99
Wt1 and retinoic acid signaling in the subcoelomic mesenchyme control the development of the pleuropericardial membranes and the sinus horns. Circ Res (2010) 0.97
The sinus venosus progenitors separate and diversify from the first and second heart fields early in development. Cardiovasc Res (2010) 0.96
Carboxypeptidase Z (CPZ) modulates Wnt signaling and regulates the development of skeletal elements in the chicken. Development (2003) 0.96
Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse. Dev Biol (2009) 0.95
Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development. Mol Cell Biol (2010) 0.95
Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation. Cell Mol Life Sci (2011) 0.95
Partial absence of pleuropericardial membranes in Tbx18- and Wt1-deficient mice. PLoS One (2012) 0.95
Semaphorin 3d signaling defects are associated with anomalous pulmonary venous connections. Nat Med (2013) 0.94
Gene expression analysis identifies novel genes participating in early murine liver development and adult liver regeneration. Differentiation (2006) 0.94
Serum-free differentiation of murine embryonic stem cells into alveolar type II epithelial cells. Cloning Stem Cells (2008) 0.94
Wnt6 is expressed in granulomatous lesions of Mycobacterium tuberculosis-infected mice and is involved in macrophage differentiation and proliferation. J Immunol (2013) 0.93
Mutations in ACY1, the gene encoding aminoacylase 1, cause a novel inborn error of metabolism. Am J Hum Genet (2006) 0.92
Comparative analysis of Neph gene expression in mouse and chicken development. Histochem Cell Biol (2011) 0.91
Slit-roundabout signaling regulates the development of the cardiac systemic venous return and pericardium. Circ Res (2012) 0.91
Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet (2013) 0.91
Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes. Mech Dev (2002) 0.89
Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1. Development (2012) 0.89
Inhibition of Sox2-dependent activation of Shh in the ventral diencephalon by Tbx3 is required for formation of the neurohypophysis. Development (2013) 0.89
Amino acid polymorphisms altering the glycosylation of IL-2 do not protect from type 1 diabetes in the NOD mouse. Proc Natl Acad Sci U S A (2009) 0.88
T-box protein Tbx18 interacts with the paired box protein Pax3 in the development of the paraxial mesoderm. J Biol Chem (2008) 0.88
Tbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1. PLoS Genet (2013) 0.86