Published in PLoS One on October 05, 2016
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev (2007) 21.13
The pathobiology of diabetic complications: a unifying mechanism. Diabetes (2005) 14.96
Role of oxidative stress in development of complications in diabetes. Diabetes (1991) 8.27
Oxidative damage and mitochondrial decay in aging. Proc Natl Acad Sci U S A (1994) 6.84
Oxidative stress as a major culprit in kidney disease in diabetes. Diabetes (2008) 4.13
Mouse models of diabetic nephropathy. J Am Soc Nephrol (2004) 3.95
A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice. Diabetes (1997) 3.83
Mouse models of diabetic nephropathy. J Am Soc Nephrol (2009) 3.74
alpha-Lipoic acid as a biological antioxidant. Free Radic Biol Med (1995) 3.58
Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney. J Biol Chem (2005) 2.98
Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy. Nat Rev Nephrol (2011) 2.92
NADPH oxidases in the kidney. Antioxid Redox Signal (2006) 2.70
Impact of genetic background on nephropathy in diabetic mice. Am J Physiol Renal Physiol (2005) 2.29
Molecular phenotyping for analyzing subtle genetic effects in mice: application to an angiotensinogen gene titration. Proc Natl Acad Sci U S A (2002) 2.08
Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim Biophys Acta (2009) 2.05
Pathogenesis, prevention, and treatment of diabetic nephropathy. Lancet (1998) 2.02
Diabetes-induced activation of nuclear transcriptional factor in the retina, and its inhibition by antioxidants. Free Radic Res (2003) 1.90
Effects of NADPH oxidase inhibitor in diabetic nephropathy. Kidney Int (2005) 1.78
1,25-Dihydroxyvitamin D3 targeting of NF-kappaB suppresses high glucose-induced MCP-1 expression in mesangial cells. Kidney Int (2007) 1.64
Endogenous production of lipoic acid is essential for mouse development. Mol Cell Biol (2005) 1.49
Nrf2-dependent induction of proteasome and Pa28αβ regulator are required for adaptation to oxidative stress. J Biol Chem (2012) 1.46
Pathogenesis of diabetic nephropathy. Exp Clin Endocrinol Diabetes (2001) 1.42
Effects of vitamin E on cardiovascular and microvascular outcomes in high-risk patients with diabetes: results of the HOPE study and MICRO-HOPE substudy. Diabetes Care (2002) 1.40
Association of monocyte chemoattractant protein-1 with renal tubular damage in diabetic nephropathy. J Diabetes Complications (2002) 1.39
Influence of genetic background on albuminuria and kidney injury in Ins2(+/C96Y) (Akita) mice. Am J Physiol Renal Physiol (2009) 1.36
Role of reactive oxygen species in the pathogenesis of diabetic nephropathy. Diabetes Res Clin Pract (2008) 1.34
Dedifferentiation of immortalized human podocytes in response to transforming growth factor-β: a model for diabetic podocytopathy. Diabetes (2011) 1.22
Expression of transforming growth factor-beta and type IV collagen in early streptozotocin-induced diabetes. Diabetes (1997) 1.21
Cytokine-induced production of monocyte chemoattractant protein-1 by cultured human mesangial cells. J Immunol (1992) 1.17
The effect of vitamin E supplementation on cardiovascular risk in diabetic individuals with different haptoglobin phenotypes. Atherosclerosis (2010) 1.08
The plasma pharmacokinetics of R-(+)-lipoic acid administered as sodium R-(+)-lipoate to healthy human subjects. Altern Med Rev (2007) 1.05
Double-blind, randomised study of the effect of combined treatment with vitamin C and E on albuminuria in Type 2 diabetic patients. Diabet Med (2001) 1.03
From lipoic acid to multi-enzyme complexes. Protein Sci (1998) 1.00
Optimizing enzymatic cycling assays: spectrophotometric determination of low levels of pyruvate and L-lactate. Anal Biochem (1996) 1.00
Lack of effect of oral vitamin C on blood pressure, oxidative stress and endothelial function in Type II diabetes. Clin Sci (Lond) (2002) 0.99
Inhibition of inflammation by pentosan polysulfate impedes the development and progression of severe diabetic nephropathy in aging C57B6 mice. Lab Invest (2011) 0.99
Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita(+/Ins2)-derived β-cells. Am J Physiol Endocrinol Metab (2013) 0.90
Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A. Biogerontology (2008) 0.89
Overexpression of catalase prevents hypertension and tubulointerstitial fibrosis and normalization of renal angiotensin-converting enzyme-2 expression in Akita mice. Am J Physiol Renal Physiol (2013) 0.87
Lipoic acid synthase (LASY): a novel role in inflammation, mitochondrial function, and insulin resistance. Diabetes (2008) 0.86
A mouse strain where basal connective tissue growth factor gene expression can be switched from low to high. PLoS One (2010) 0.83
The role of lipoic acid in the treatment of diabetic polyneuropathy. Drug Metab Rev (1997) 0.81
Reduced expression of lipoic acid synthase accelerates diabetic nephropathy. J Am Soc Nephrol (2011) 0.81
Exendin-4 attenuates renal tubular injury by decreasing oxidative stress and inflammation in streptozotocin-induced diabetic mice. Growth Factors (2016) 0.78