1,25-Dihydroxyvitamin D3 targeting of NF-kappaB suppresses high glucose-induced MCP-1 expression in mesangial cells.

PubWeight™: 1.64‹?› | Rank: Top 3%

🔗 View Article (PMID 17507908)

Published in Kidney Int on May 16, 2007

Authors

Z Zhang1, W Yuan, L Sun, F L Szeto, K E Wong, X Li, J Kong, Y C Li

Author Affiliations

1: Department of Medicine and Committee on Molecular Metabolism and Nutrition, Division of Biological Sciences, The University of Chicago, Chicago, Illinois 60637, USA.

Articles citing this

Activated vitamin D attenuates left ventricular abnormalities induced by dietary sodium in Dahl salt-sensitive animals. Proc Natl Acad Sci U S A (2007) 2.25

Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: blockade of compensatory renin increase. Proc Natl Acad Sci U S A (2008) 2.06

Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kappaB signaling. J Am Soc Nephrol (2008) 1.84

The world pandemic of vitamin D deficiency could possibly be explained by cellular inflammatory response activity induced by the renin-angiotensin system. Am J Physiol Cell Physiol (2013) 1.56

Possible renoprotection by vitamin D in chronic renal disease: beyond mineral metabolism. Nat Rev Nephrol (2009) 1.51

Vitamin D receptor attenuates renal fibrosis by suppressing the renin-angiotensin system. J Am Soc Nephrol (2010) 1.50

Monocyte Chemoattractant Protein 1 (MCP-1) in obesity and diabetes. Cytokine (2012) 1.38

Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation. Kidney Int (2008) 1.36

1,25-Dihydroxyvitamin D3 suppresses high glucose-induced angiotensinogen expression in kidney cells by blocking the NF-{kappa}B pathway. Am J Physiol Renal Physiol (2009) 1.31

1,25-Dihydroxyvitamin D promotes negative feedback regulation of TLR signaling via targeting microRNA-155-SOCS1 in macrophages. J Immunol (2013) 1.24

Vitamin D and chronic kidney disease. Ethn Dis (2009) 1.20

A nonclassical vitamin D receptor pathway suppresses renal fibrosis. J Clin Invest (2013) 1.16

Long-term therapeutic effect of vitamin D analog doxercalciferol on diabetic nephropathy: strong synergism with AT1 receptor antagonist. Am J Physiol Renal Physiol (2009) 1.13

1,25-Dihydroxyvitamin D3 inhibits the cytokine-induced secretion of MCP-1 and reduces monocyte recruitment by human preadipocytes. Int J Obes (Lond) (2012) 1.13

Fenofibrate attenuates tubulointerstitial fibrosis and inflammation through suppression of nuclear factor-κB and transforming growth factor-β1/Smad3 in diabetic nephropathy. Exp Biol Med (Maywood) (2010) 1.08

1,25-Dihydroxyvitamin D₃ suppresses inflammation-induced expression of plasminogen activator inhibitor-1 by blocking nuclear factor-κB activation. Arch Biochem Biophys (2010) 1.02

Vitamin D receptor inhibits nuclear factor κB activation by interacting with IκB kinase β protein. J Biol Chem (2013) 1.02

Oral supplementation with cholecalciferol 800 IU ameliorates albuminuria in Chinese type 2 diabetic patients with nephropathy. PLoS One (2012) 1.02

Vitamin D status and its association with morbidity including wasting and opportunistic illnesses in HIV-infected women in Tanzania. AIDS Patient Care STDS (2011) 1.01

25 (OH) vitamin D levels and renal disease progression in patients with type 2 diabetic nephropathy and blockade of the renin-angiotensin system. Clin J Am Soc Nephrol (2013) 1.01

Pathophysiological role and therapeutic implications of inflammation in diabetic nephropathy. World J Diabetes (2012) 1.00

Vitamin D: roles in renal and cardiovascular protection. Curr Opin Nephrol Hypertens (2012) 0.99

Differential effects of 1α,25-dihydroxycholecalciferol on MCP-1 and adiponectin production in human white adipocytes. Eur J Nutr (2011) 0.95

Effects of high-dose cholecalciferol on serum markers of inflammation and immunity in patients with early chronic kidney disease. Eur J Clin Nutr (2013) 0.95

Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism. Am J Physiol Renal Physiol (2011) 0.92

Inflammation in diabetic kidney disease. World J Diabetes (2014) 0.91

Nuclear NF-κB p65 in peripheral blood mononuclear cells correlates with urinary MCP-1, RANTES and the severity of type 2 diabetic nephropathy. PLoS One (2014) 0.88

1,25-Dihydroxyvitamin D Protects Intestinal Epithelial Barrier by Regulating the Myosin Light Chain Kinase Signaling Pathway. Inflamm Bowel Dis (2015) 0.87

Nuclear hormone receptors in diabetic nephropathy. Nat Rev Nephrol (2010) 0.86

n-3 Fatty acids block TNF-α-stimulated MCP-1 expression in rat mesangial cells. Am J Physiol Renal Physiol (2011) 0.86

MicroRNA-mediated mechanism of vitamin D regulation of innate immune response. J Steroid Biochem Mol Biol (2013) 0.85

Evidence that abnormally large seasonal declines in vitamin D status may trigger SLE flare in non-African Americans. Lupus (2012) 0.85

VDR attenuates acute lung injury by blocking Ang-2-Tie-2 pathway and renin-angiotensin system. Mol Endocrinol (2013) 0.85

Lower levels of 25-hydroxyvitamin D3 are associated with a higher prevalence of microvascular complications in patients with type 2 diabetes. BMJ Open Diabetes Res Care (2015) 0.85

Nuclear receptors in renal disease. Biochim Biophys Acta (2011) 0.84

22-Oxacalcitriol prevents progression of peritoneal fibrosis in a mouse model. Perit Dial Int (2012) 0.82

Association of vitamin D and vitamin D receptor gene polymorphisms with chronic inflammation, insulin resistance and metabolic syndrome components in type 2 diabetic Egyptian patients. Meta Gene (2014) 0.81

Niacin Suppresses Progression of Atherosclerosis by Inhibiting Vascular Inflammation and Apoptosis of Vascular Smooth Muscle Cells. Med Sci Monit (2015) 0.79

Cobalt chloride attenuates oxidative stress and inflammation through NF-κB inhibition in human renal proximal tubular epithelial cells. J Korean Med Sci (2014) 0.78

Vitamin D levels and microvascular complications in type 2 diabetes. Indian J Endocrinol Metab (2014) 0.77

Diabetic Kidney Disease: Pathophysiology and Therapeutic Targets. J Diabetes Res (2015) 0.77

Nuclear hormone receptors in podocytes. Cell Biosci (2012) 0.77

Inflammation, vitamin D and dendritic cell precursors in chronic kidney disease. Clin Exp Immunol (2016) 0.75

Influence of Different Levels of Lipoic Acid Synthase Gene Expression on Diabetic Nephropathy. PLoS One (2016) 0.75

Effect of paricalcitol and enalapril on renal inflammation/oxidative stress in atherosclerosis. World J Biol Chem (2015) 0.75

Analysis of Adequacy of 25-Hydroxi vitamin D3 Supplementation in Patients on Hemodialysis and Parathormone, Calcium and Phosphorus Level in the Blood of These Patients. Mater Sociomed (2015) 0.75

Vitamin D3 ameliorates podocyte injury through the nephrin signalling pathway. J Cell Mol Med (2017) 0.75

ISN Forefronts Symposium 2015: Nuclear Receptors and Diabetic Nephropathy. KI Rep (2016) 0.75

Calcitriol Ameliorates AngiotensinII-Induced Renal Injury Partly via Upregulating A20. Inflammation (2017) 0.75

Articles by these authors

Involvement of chemokine receptors in breast cancer metastasis. Nature (2001) 26.07

Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science (2000) 16.04

Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda. Lancet (2001) 13.32

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science (1995) 13.15

Elastography: a quantitative method for imaging the elasticity of biological tissues. Ultrason Imaging (1991) 11.44

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet (2000) 8.33

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell (1996) 8.25

Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis. Nature (2000) 7.37

Sequence complexity of disordered protein. Proteins (2001) 6.97

Statistical tests for detection of misspecified relationships by use of genome-screen data. Am J Hum Genet (2000) 6.96

Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell (2000) 6.81

Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol (2001) 5.17

Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. Circ Res (2001) 5.08

Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20. Cell (2001) 4.92

Molecular cloning and functional analysis of a novel macrolide-resistance determinant, mefA, from Streptococcus pyogenes. Mol Microbiol (1996) 4.86

Podocyte loss and progressive glomerular injury in type II diabetes. J Clin Invest (1997) 4.83

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science (1997) 4.70

Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma. Eur Respir J (2009) 4.54

Graphene as a subnanometre trans-electrode membrane. Nature (2010) 4.45

mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae. Antimicrob Agents Chemother (1997) 4.38

SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling. Mol Cell Biol (2000) 4.30

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome. Cell (1993) 4.30

Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip'. J Gen Virol (2001) 4.25

SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res (1999) 4.23

Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes. Am J Physiol (1995) 4.15

GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid. Nature (1998) 4.09

Clonal and antigenic analysis of serogroup A Neisseria meningitidis with particular reference to epidemiological features of epidemic meningitis in the People's Republic of China. Infect Immun (1992) 4.02

Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity (1996) 3.91

Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis). Cytometry (1997) 3.90

Transmissibility of Pseudomonas cepacia infection in clinic patients and lung-transplant recipients with cystic fibrosis. N Engl J Med (1994) 3.89

Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo. Gene Ther (2003) 3.85

Mutations altering the moloney murine leukemia virus p12 Gag protein affect virion production and early events of the virus life cycle. EMBO J (1999) 3.67

Structural basis for DNA bending by the architectural transcription factor LEF-1. Nature (1995) 3.58

Interaction of NPR1 with basic leucine zipper protein transcription factors that bind sequences required for salicylic acid induction of the PR-1 gene. Proc Natl Acad Sci U S A (1999) 3.56

CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri. EMBO Rep (2001) 3.55

A Myb-related transcription factor is involved in the phytochrome regulation of an Arabidopsis Lhcb gene. Plant Cell (1997) 3.54

Ordered restriction maps of Saccharomyces cerevisiae chromosomes constructed by optical mapping. Science (1993) 3.54

Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine. J Virol (1992) 3.46

Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure. Circ Res (1999) 3.35

Non-Alu family interspersed repeats in human DNA and their transcriptional activity. Nucleic Acids Res (1984) 3.30

Conversion of diploidy to haploidy. Nature (2000) 3.28

Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling. Science (2001) 3.23

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene (1999) 3.23

Incidence of open-angle glaucoma: the Barbados Eye Studies. The Barbados Eye Studies Group. Arch Ophthalmol (2001) 3.20

Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains. Proc Natl Acad Sci U S A (1996) 3.17

Hypertrophic gastropathy in Helicobacter felis-infected wild-type C57BL/6 mice and p53 hemizygous transgenic mice. Gastroenterology (1996) 3.15

Age-related changes in the collagen network and toughness of bone. Bone (2002) 3.13

Regulated chromosomal DNA replication in the absence of a nucleus. Mol Cell (1998) 3.11

Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites. Eur J Neurosci (1999) 3.10

Chronic proliferative hepatitis in A/JCr mice associated with persistent Helicobacter hepaticus infection: a model of helicobacter-induced carcinogenesis. Infect Immun (1996) 3.09

Renoprotective role of the vitamin D receptor in diabetic nephropathy. Kidney Int (2007) 3.06

Familial risk in testicular cancer as a clue to a heritable and environmental aetiology. Br J Cancer (2004) 2.97

A randomized, controlled effectiveness trial of an AIDS prevention program for low-income African-American youths. Arch Pediatr Adolesc Med (1996) 2.95

Effectiveness of laser therapy and topical desensitising agents in treating dentine hypersensitivity: a systematic review. J Oral Rehabil (2011) 2.91

Antigens displayed on murine B lymphocyte precursors. J Immunol (1981) 2.91

Dedifferentiation of epidermal cells to stem cells in vivo. Lancet (2001) 2.90

Multiple independent loci within the human cytomegalovirus unique short region down-regulate expression of major histocompatibility complex class I heavy chains. J Virol (1995) 2.87

Dendrimer-encapsulated metal nanoparticles: synthesis, characterization, and applications to catalysis. Acc Chem Res (2001) 2.85

Expression of Light-Harvesting Chlorophyll a/b-Protein Genes Is Phytochrome-Regulated in Etiolated Arabidopsis thaliana Seedlings. Plant Physiol (1988) 2.85

Interfacial catalysis: the mechanism of phospholipase A2. Science (1990) 2.84

A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis. Cell (1993) 2.80

An extreme distortion of the Van Allen belt arising from the 'Hallowe'en' solar storm in 2003. Nature (2004) 2.76

Positional cloning of the mouse saccharin preference (Sac) locus. Chem Senses (2001) 2.75

Dentinogenesis imperfecta 1 with or without progressive hearing loss is associated with distinct mutations in DSPP. Nat Genet (2001) 2.75

Determination of the MRI contrast agent concentration time course in vivo following bolus injection: effect of equilibrium transcytolemmal water exchange. Magn Reson Med (2000) 2.75

Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo. J Exp Med (1997) 2.71

Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation. EMBO J (1997) 2.71

PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor. Nat Cell Biol (2001) 2.70

Diffusion tensor imaging of acute mild traumatic brain injury in adolescents. Neurology (2008) 2.67

Adhesion formation after previous caesarean section-a meta-analysis and systematic review. BJOG (2010) 2.66

Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group. Neurology (2000) 2.64

Catalytic subunit of DNA-dependent protein kinase: impact on lymphocyte development and tumorigenesis. Proc Natl Acad Sci U S A (1999) 2.58

Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR. Genomics (1992) 2.55

Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J Exp Med (1995) 2.52

Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells. Cell Death Differ (2007) 2.51

Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. Nature (1999) 2.50

TATA element recognition by the TATA box-binding protein has been conserved throughout evolution. Genes Dev (1999) 2.50

Computed tomography imaging features and classification of isolated dissection of the superior mesenteric artery. Eur J Vasc Endovasc Surg (2013) 2.50

Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor. J Exp Med (1993) 2.49

Development of a culturally, theoretically and developmentally based survey instrument for assessing risk behaviors among African-American early adolescents living in urban low-income neighborhoods. AIDS Educ Prev (1995) 2.48

Persistent hepatitis and enterocolitis in germfree mice infected with Helicobacter hepaticus. Infect Immun (1996) 2.47

The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II. Mol Cell (2001) 2.45

IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family. J Biol Chem (1999) 2.43

Characterization of the two small subunits of Saccharomyces cerevisiae DNA polymerase delta. J Biol Chem (1998) 2.42

Generation of broad-spectrum disease resistance by overexpression of an essential regulatory gene in systemic acquired resistance. Proc Natl Acad Sci U S A (1998) 2.40

SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Cancer Res (2000) 2.39

High-level production of uniformly ¹⁵N- and ¹³C-enriched fusion proteins in Escherichia coli. J Biomol NMR (1996) 2.38

Effectiveness of the 40 adolescent AIDS-risk reduction interventions: a quantitative review. J Adolesc Health (1997) 2.37

Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons. Cell (1999) 2.35

MHC class I-related neonatal Fc receptor for IgG is functionally expressed in monocytes, intestinal macrophages, and dendritic cells. J Immunol (2001) 2.33

Incidence trends and risk factors of carcinoid tumors: a nationwide epidemiologic study from Sweden. Cancer (2001) 2.32

Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1. Oncogene (2008) 2.31

LAI inversion algorithm based on directional reflectance kernels. J Environ Manage (2006) 2.31

High-throughput isolation of Caenorhabditis elegans deletion mutants. Genome Res (1999) 2.29

Comparison of deoxyoligonucleotide and tRNA(Lys-3) as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/template-switching reaction. J Biol Chem (1994) 2.28

Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. J Exp Med (1995) 2.24

Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin. J Biol Chem (1999) 2.23

Equilibrium transcytolemmal water-exchange kinetics in skeletal muscle in vivo. Magn Reson Med (1999) 2.21