High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD - results from the ECLIPSE study.

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Published in Respir Res on October 04, 2016

Authors

Jannie M B Sand1,2, Diana J Leeming3, Inger Byrjalsen3, Asger R Bihlet3, Peter Lange4,5, Ruth Tal-Singer6, Bruce E Miller6, Morten A Karsdal3, Jørgen Vestbo7

Author Affiliations

1: Nordic Bioscience, Herlev, Denmark. jsa@nordicbioscience.com.
2: Section of Social Medicine, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark. jsa@nordicbioscience.com.
3: Nordic Bioscience, Herlev, Denmark.
4: Section of Social Medicine, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark.
5: Section of Respiratory Medicine, Hvidovre Hospital, Hvidovre, Denmark.
6: Respiratory Therapy Area Unit, GSK Research and Development, King of Prussia, PA, USA.
7: Centre for Respiratory Medicine and Allergy, Manchester Academic Science Centre, The University of Manchester and University Hospital South Manchester NHS Foundation Trust, Manchester, UK.

Associated clinical trials:

Evaluation of COPD (Chronic Obstructive Pulmonary Disease) to Longitudinally Identify Predictive Surrogate Endpoints (ECLIPSE) | NCT00292552

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