| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay.
|
Radiat Res
|
1990
|
4.60
|
|
2
|
Intermittent blood flow in a murine tumor: radiobiological effects.
|
Cancer Res
|
1987
|
2.85
|
|
3
|
Radiation response of multicell spheroids--an in vitro tumour model.
|
Curr Top Radiat Res Q
|
1976
|
2.73
|
|
4
|
Acute hypoxia in tumors: implications for modifiers of radiation effects.
|
Int J Radiat Oncol Biol Phys
|
1986
|
1.84
|
|
5
|
Effects of intercellular contact on repair of radiation damage.
|
Exp Cell Res
|
1972
|
1.76
|
|
6
|
Use of Hoechst 33342 for cell selection from multicell systems.
|
J Histochem Cytochem
|
1982
|
1.72
|
|
7
|
The use of fluorescent probes to identify regions of transient perfusion in murine tumors.
|
Int J Radiat Oncol Biol Phys
|
1989
|
1.71
|
|
8
|
Cell selection from a murine tumour using the fluorescent probe Hoechst 33342.
|
Br J Cancer
|
1985
|
1.57
|
|
9
|
Cytotoxicity, Mutagenicity and DNA damage by Hoechst 33342.
|
J Histochem Cytochem
|
1982
|
1.56
|
|
10
|
Pharmacokinetics, binding and distribution of Hoechst 33342 in spheroids and murine tumours.
|
Br J Cancer
|
1985
|
1.47
|
|
11
|
The effects of nitrobenzene derivatives on oxygen utilization and radiation response of an in vitro tumor model.
|
Radiat Res
|
1976
|
1.45
|
|
12
|
Drug and radiation resistance in spheroids: cell contact and kinetics.
|
Cancer Metastasis Rev
|
1994
|
1.42
|
|
13
|
Factors influencing DNA migration from individual cells subjected to gel electrophoresis.
|
Exp Cell Res
|
1992
|
1.30
|
|
14
|
Flow cytometry studies of intracellular adriamycin in multicell spheroids in vitro.
|
Cancer Res
|
1981
|
1.29
|
|
15
|
Gel electrophoresis of individual cells to quantify hypoxic fraction in human breast cancers.
|
Cancer Res
|
1993
|
1.25
|
|
16
|
Flow cytometry studies of intracellular adriamycin in single cells in vitro.
|
Cancer Res
|
1981
|
1.22
|
|
17
|
Comparison between pimonidazole binding, oxygen electrode measurements, and expression of endogenous hypoxia markers in cancer of the uterine cervix.
|
Cytometry B Clin Cytom
|
2006
|
1.20
|
|
18
|
Characterization of radiolabeled fluoromisonidazole as a probe for hypoxic cells.
|
Radiat Res
|
1987
|
1.18
|
|
19
|
Effects of sensitizers on cell respiration: 1. Factors influencing the effects of hypoxic cell radiosensitizers on oxygen utilization of tumour and cultured mammalian cells.
|
Br J Cancer Suppl
|
1978
|
1.16
|
|
20
|
Variable radiobiological responses of spheroids.
|
Radiat Res
|
1980
|
1.10
|
|
21
|
Chemosensitivity testing in V79 spheroids: drug delivery and cellular microenvironment.
|
J Natl Cancer Inst
|
1986
|
1.10
|
|
22
|
Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells.
|
J Natl Cancer Inst
|
1990
|
1.09
|
|
23
|
Growth and cellular characteristics of multicell spheroids.
|
Recent Results Cancer Res
|
1984
|
1.07
|
|
24
|
Detection of hypoxic cells in a murine tumor with the use of the comet assay.
|
J Natl Cancer Inst
|
1992
|
1.05
|
|
25
|
Fluorescent nitroheterocycles for identifying hypoxic cells.
|
Cancer Res
|
1983
|
1.04
|
|
26
|
Intermittent blood flow in the KHT sarcoma--flow cytometry studies using Hoechst 33342.
|
Br J Cancer
|
1990
|
1.04
|
|
27
|
Effects of sensitizers on cell respiration: III. The effects of hypoxic cell radiosensitizers on oxidative metabolism and the radiation response of an in vitro tumour model.
|
Br J Cancer Suppl
|
1978
|
1.03
|
|
28
|
Hypoxic cells in an in vitro tumour model.
|
Int J Radiat Biol Relat Stud Phys Chem Med
|
1973
|
1.02
|
|
29
|
Cell killing, radiosensitization and cell cycle redistribution induced by chronic hypoxia.
|
Int J Radiat Oncol Biol Phys
|
1984
|
1.01
|
|
30
|
Effects of hyperthermia on the cycling, noncycling, and hypoxic cells of irradiated and unirradiated multicell spheroids.
|
Radiat Res
|
1978
|
0.99
|
|
31
|
Measurements of relative biological effectiveness of the 70 MeV proton beam at TRIUMF using Chinese hamster V79 cells and the high-precision cell sorter assay.
|
Radiat Res
|
1996
|
0.98
|
|
32
|
Activation of radiosensitizers by hypoxic cells.
|
Br J Cancer Suppl
|
1978
|
0.98
|
|
33
|
Use of a cell sorter for assays of cell clonogenicity.
|
Cancer Res
|
1986
|
0.97
|
|
34
|
Analysis of DNA damage in individual cells.
|
Methods Cell Biol
|
2001
|
0.97
|
|
35
|
Radioprotection by WR-2721 in vitro at low oxygen tensions: implications for its mechanisms of action.
|
Br J Cancer
|
1983
|
0.96
|
|
36
|
Hypoxic fractions measured in murine tumors and normal tissues using the comet assay.
|
Int J Radiat Oncol Biol Phys
|
1994
|
0.95
|
|
37
|
Radiosensitization of hypoxic cells of an in vitro tumor model by respiratory inhibitors.
|
Radiat Res
|
1977
|
0.94
|
|
38
|
Isolation of cell subpopulations from in vitro tumor models according to sedimentation velocity.
|
Cancer Res
|
1975
|
0.94
|
|
39
|
Comparison between the comet assay and pimonidazole binding for measuring tumour hypoxia.
|
Br J Cancer
|
2000
|
0.93
|
|
40
|
The comet assay in clinical practice.
|
Acta Oncol
|
1999
|
0.93
|
|
41
|
Letter: Modification of the radiation response of an in vitro tumour model by control of cellular respiration.
|
Int J Radiat Biol Relat Stud Phys Chem Med
|
1974
|
0.92
|
|
42
|
Characterization of a carbocyanine derivative as a fluorescent penetration probe.
|
Cytometry
|
1987
|
0.92
|
|
43
|
Oxygen enhancement ratio in V79 spheroids.
|
Radiat Res
|
1983
|
0.90
|
|
44
|
The radiosensitizing and toxic effects of RSU-1069 on hypoxic cells in a murine tumor.
|
Int J Radiat Oncol Biol Phys
|
1986
|
0.90
|
|
45
|
Adriamycin: a possible indirect radiosensitizer of hypoxic tumor cells.
|
Radiology
|
1976
|
0.87
|
|
46
|
Growth and radiation survival characteristics of V79-171b Chinese hamster cells: a possible influence of intercellular contact.
|
Radiat Res
|
1973
|
0.86
|
|
47
|
Interaction of etoposide and cisplatin in an in vitro tumor model.
|
Cancer Treat Rep
|
1987
|
0.86
|
|
48
|
Evidence for intermittent radiobiological hypoxia in experimental tumour systems.
|
Biomed Biochim Acta
|
1989
|
0.86
|
|
49
|
Cell cycle kinetics in an in vitro tumor model.
|
Cell Tissue Kinet
|
1976
|
0.85
|
|
50
|
Apoptosis: an indicator of radiosensitivity in vitro?
|
Int J Radiat Biol
|
1997
|
0.85
|
|
51
|
Cure, regression and cell survival: a comparison of common radiobiological endpoints using an in vitro tumour model.
|
Br J Radiol
|
1975
|
0.84
|
|
52
|
Repair and reoxygenation following irradiation of an in vitro tumor model.
|
Int J Radiat Oncol Biol Phys
|
1977
|
0.83
|
|
53
|
Detection of subpopulations resistant to DNA-damaging agents in spheroids and murine tumours.
|
Mutat Res
|
1997
|
0.83
|
|
54
|
Radiation-induced DNA damage in V79 spheroids and monolayers.
|
Radiat Res
|
1979
|
0.83
|
|
55
|
Cell contact as a possible contribution to radiation resistance of some tumours.
|
Br J Radiol
|
1972
|
0.83
|
|
56
|
Dependence of the radiation response of an in vitro tumor model on cell cycle effects.
|
Cancer Res
|
1973
|
0.82
|
|
57
|
Cell kinetics and repopulation mechanisms during multifraction irradiation of spheroids.
|
Radiother Oncol
|
1998
|
0.82
|
|
58
|
Irradiation of multi-cell spheroids with fast neutrons versus X-rays: a qualitative difference in sub-lethal damage repair capacity or kinetics.
|
Int J Radiat Biol Relat Stud Phys Chem Med
|
1976
|
0.82
|
|
59
|
Effect of intercellular contact on DNA conformation, radiation-induced DNA damage, and mutation in Chinese hamster V79 cells.
|
Radiat Res
|
1985
|
0.81
|
|
60
|
The comet assay: a new method to examine heterogeneity associated with solid tumors.
|
Nat Med
|
1998
|
0.81
|
|
61
|
Calibration of flow cytometry detector systems.
|
Cytometry
|
1981
|
0.81
|
|
62
|
Cytotoxicity of RSU 1069 in spheroids and murine tumors.
|
Int J Radiat Oncol Biol Phys
|
1987
|
0.80
|
|
63
|
Radiosensitization by nifuroxime of the hypoxic cells in an in vitro tumour model.
|
Int J Radiat Biol Relat Stud Phys Chem Med
|
1972
|
0.80
|
|
64
|
The response of hypoxic cells in SCCVII murine tumors to treatment with cisplatin and x rays.
|
Int J Radiat Oncol Biol Phys
|
1991
|
0.80
|
|
65
|
DNA conformation of Chinese hamster V79 cells and sensitivity to ionizing radiation.
|
Radiat Res
|
1986
|
0.80
|
|
66
|
Comparison between the binding of [3H]misonidazole and AF-2 in Chinese hamster V79 spheroids.
|
Radiat Res
|
1986
|
0.80
|
|
67
|
The enhanced radiation response of in vitro tumor models to insulin.
|
Int J Radiat Oncol Biol Phys
|
1979
|
0.80
|
|
68
|
Use of the comet assay for assessment of drug resistance and its modulation in vivo.
|
Br J Cancer
|
1998
|
0.80
|
|
69
|
Roles of thiols in cellular radiosensitivity.
|
Int J Radiat Oncol Biol Phys
|
1984
|
0.80
|
|
70
|
Development of apoptosis and polyploidy in human lymphoblast cells as a function of position in the cell cycle at the time of irradiation.
|
Radiat Res
|
1996
|
0.79
|
|
71
|
Development of tetraploidy in V79 spheroids.
|
In Vitro
|
1982
|
0.78
|
|
72
|
Etoposide sensitivity and topoisomerase II activity in Chinese hamster V79 monolayers and small spheroids.
|
Int J Radiat Biol
|
1991
|
0.78
|
|
73
|
The radiation response of asynchronous cells at low dose: evidence of substructure.
|
Radiat Res
|
1991
|
0.78
|
|
74
|
Substructure in the radiation survival response at low dose in cells of human tumor cell lines.
|
Radiat Res
|
1996
|
0.78
|
|
75
|
The enhanced radiation response of an in vitro tumour model by cyanide released from hydrolysed amygdalin.
|
Int J Radiat Biol Relat Stud Phys Chem Med
|
1978
|
0.77
|
|
76
|
Repopulation characteristics and cell kinetic parameters resulting from multi-fraction irradiation of xenograft tumors in SCID mice.
|
Int J Radiat Oncol Biol Phys
|
1999
|
0.77
|
|
77
|
Potentiation of radiation lethality by hyperthermia in a tumor model: effects of sequence, degree, and duration of heating.
|
Int J Radiat Oncol Biol Phys
|
1978
|
0.77
|
|
78
|
Misonidazole binding in SCCVII tumors in relation to the tumor blood supply.
|
Int J Radiat Oncol Biol Phys
|
1989
|
0.77
|
|
79
|
Potentiation of CCNU toxicity by AF-2 in V79 spheroids: implications for mechanisms of chemosensitization.
|
Int J Radiat Oncol Biol Phys
|
1986
|
0.77
|
|
80
|
DNA strand breakage in Chinese hamster V79 cells caused by low levels of incorporated [3H] and [14C]thymidine.
|
Int J Radiat Biol Relat Stud Phys Chem Med
|
1987
|
0.77
|
|
81
|
Cellular oxygen utilization and radiation response of V-79 spheroids.
|
Adv Exp Med Biol
|
1983
|
0.76
|
|
82
|
Radiation-resistant tumor cells may be more sensitive in vitro.
|
Cancer Res
|
1972
|
0.76
|
|
83
|
Penetration of AF-2 and 4NQO into multicell spheroids.
|
Environ Mutagen
|
1983
|
0.76
|
|
84
|
Effects of lucanthone on Chinese hamster V-79 cells. I. Interaction with radiation in monolayers and spheroids.
|
Int J Radiat Oncol Biol Phys
|
1980
|
0.76
|
|
85
|
Repair during multifraction exposures: spheroids versus monolayers.
|
Br J Cancer Suppl
|
1984
|
0.76
|
|
86
|
The biological activity of cisplatin and dibromodulcitol in combination therapy.
|
Br J Cancer
|
1995
|
0.75
|
|
87
|
Drug-induced alterations in tumour perfusion yield increases in tumour cell radiosensitivity.
|
Br J Cancer
|
2001
|
0.75
|
|
88
|
Effects of sensitizers on cell respiration: II. The effects of hypoxic cell sensitizers on oxygen utilization in cellular and chemical models.
|
Br J Cancer Suppl
|
1978
|
0.75
|
|
89
|
Nitropyrrole radiosensitizers: structure function relationships.
|
Br J Cancer Suppl
|
1978
|
0.75
|
|
90
|
Fast neutron effects on multicell spheroids.
|
Br J Radiol
|
1977
|
0.75
|
|
91
|
Effects of lucanthone on Chinese hamster V-79 cells. II. Damage to DNA.
|
Int J Radiat Oncol Biol Phys
|
1980
|
0.75
|
|
92
|
Characterization of the uptake and toxicity of a fluorescent thiol reagent.
|
Cytometry
|
1983
|
0.75
|
|
93
|
Survival at low dose in asynchronous and partially synchronized Chinese hamster V79-171 cells.
|
Radiat Res
|
1993
|
0.75
|
|
94
|
Low dose-rate irradiation of multicell spheroids.
|
Int J Radiat Oncol Biol Phys
|
1979
|
0.75
|
|
95
|
Combination adriamycin/misonidazole toxicity in V79 spheroids.
|
Int J Radiat Oncol Biol Phys
|
1982
|
0.75
|
|
96
|
Radiosensitization of hypoxic cells at low doses.
|
Int J Radiat Oncol Biol Phys
|
1986
|
0.75
|
|
97
|
Cell kinetics and repopulation parameters of irradiated xenograft tumours in SCID mice: comparison of two dose-fractionation regimens.
|
Eur J Cancer
|
1999
|
0.75
|
|
98
|
Flow cytometry techniques for studying cellular thiols.
|
Radiat Res
|
1983
|
0.75
|
|
99
|
Respiration-induced oxygen gradients in cultured mammalian cells.
|
Int J Radiat Biol
|
1990
|
0.75
|
|
100
|
Effects of injection volume on the tissue dose, dose rate, and therapeutic potential intraperitoneal 32p.
|
Radiology
|
1981
|
0.75
|
|
101
|
On the mechanism for enhancement of tumor radiation to hyperbaric oxygen in sodium pentobarbital anesthetized rodents.
|
Adv Exp Med Biol
|
1984
|
0.75
|
|
102
|
The oxygen enhancement ratio for high energy neutrons.
|
Br J Radiol
|
1980
|
0.75
|
|
103
|
Radiation studies with spheroids.
|
Recent Results Cancer Res
|
1984
|
0.75
|
|
104
|
Repair, redistribution and repopulation in V79 spheroids during multifraction irradiation.
|
Cell Prolif
|
1994
|
0.75
|