PD-L1 is upregulated by EBV-driven LMP1 through NF-κB pathway and correlates with poor prognosis in natural killer/T-cell lymphoma.

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Published in J Hematol Oncol on October 13, 2016

Authors

Xi-Wen Bi1,2, Hua Wang1,3, Wen-Wen Zhang1,4, Jing-Hua Wang1,3, Wen-Jian Liu1,3, Zhong-Jun Xia1,3, Hui-Qiang Huang1,2, Wen-Qi Jiang1,2, Yu-Jing Zhang1,4, Liang Wang5,6

Author Affiliations

1: Department of Hematologic Oncology, State Key Laboratory of Oncology in South China/Cancer Center, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510060, People's Republic of China.
2: Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, People's Republic of China.
3: Department of Hematologic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, People's Republic of China.
4: Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, People's Republic of China.
5: Department of Hematologic Oncology, State Key Laboratory of Oncology in South China/Cancer Center, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510060, People's Republic of China. wangliang@sysucc.org.cn.
6: Department of Hematologic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, People's Republic of China. wangliang@sysucc.org.cn.

Associated clinical trials:

Study of MK-3475 in Relapsed or Refractory Peripheral T-cell Non-Hodgkin Lymphoma | NCT02535247

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