Published in Mol Psychiatry on October 18, 2016
Wnt signaling networks in autism spectrum disorder and intellectual disability. J Neurodev Disord (2016) 0.75
Neurodevelopmental Perspectives on Wnt Signaling in Psychiatry. Mol Neuropsychiatry (2017) 0.75
Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron (2000) 22.02
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. Nature (2012) 14.76
A polygenic burden of rare disruptive mutations in schizophrenia. Nature (2014) 5.99
The contribution of de novo coding mutations to autism spectrum disorder. Nature (2014) 5.94
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. J Neurosci (2014) 5.52
Synaptic, transcriptional and chromatin genes disrupted in autism. Nature (2014) 5.30
Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling. Cell (2000) 4.35
Dendritic spines: cellular specializations imparting both stability and flexibility to synaptic function. Annu Rev Neurosci (1994) 4.15
Schizophrenia risk from complex variation of complement component 4. Nature (2016) 3.84
Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism. Proc Natl Acad Sci U S A (2008) 3.74
WNTs modulate cell fate and behavior during vertebrate development. Trends Genet (1997) 3.44
Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test. Neurosci Biobehav Rev (2005) 3.32
Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests. Brain Res (1999) 3.27
Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism. Cell (2013) 2.94
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nat Neurosci (2010) 2.90
Convergence of genes and cellular pathways dysregulated in autism spectrum disorders. Am J Hum Genet (2014) 2.84
Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice. Proc Natl Acad Sci U S A (2006) 2.32
A de novo convergence of autism genetics and molecular neuroscience. Trends Neurosci (2013) 2.24
Dixdc1 is a critical regulator of DISC1 and embryonic cortical development. Neuron (2010) 2.08
Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice. Autism Res (2008) 2.08
A divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubules. J Cell Biol (2004) 1.90
Assaying beta-catenin/TCF transcription with beta-catenin/TCF transcription-based reporter constructs. Methods Mol Biol (2008) 1.77
GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine. Neuropsychopharmacology (2013) 1.37
DISC1 at 10: connecting psychiatric genetics and neuroscience. Trends Mol Med (2011) 1.34
Validating GSK3 as an in vivo target of lithium action. Biochem Soc Trans (2009) 1.27
Neuronal morphometry directly from bitmap images. Nat Methods (2014) 1.23
Expanded characterization of the social interaction abnormalities in mice lacking Dvl1. Genes Brain Behav (2004) 1.17
Axin contains three separable domains that confer intramolecular, homodimeric, and heterodimeric interactions involved in distinct functions. J Biol Chem (2004) 1.16
Ccd1, a novel protein with a DIX domain, is a positive regulator in the Wnt signaling during zebrafish neural patterning. Curr Biol (2003) 1.15
Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections. Dialogues Clin Neurosci (2014) 1.15
A SnoN-Ccd1 pathway promotes axonal morphogenesis in the mammalian brain. J Neurosci (2009) 1.09
Constellation of HCN channels and cAMP regulating proteins in dendritic spines of the primate prefrontal cortex: potential substrate for working memory deficits in schizophrenia. Cereb Cortex (2012) 1.08
The action of antidepressants on the glutamate system: regulation of glutamate release and glutamate receptors. Biol Psychiatry (2012) 1.04
An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential. Mol Cell (2014) 1.02
Wnt signaling in vertebrate neural development and function. J Neuroimmune Pharmacol (2012) 1.00
The DIX domain protein coiled-coil-DIX1 inhibits c-Jun N-terminal kinase activation by Axin and dishevelled through distinct mechanisms. J Biol Chem (2004) 0.99
DIXDC1 isoform, l-DIXDC1, is a novel filamentous actin-binding protein. Biochem Biophys Res Commun (2006) 0.98
Molecular basis of lithium action: integration of lithium-responsive signaling and gene expression networks. Mol Psychiatry (2003) 0.93
Dact1 is a postsynaptic protein required for dendrite, spine, and excitatory synapse development in the mouse forebrain. J Neurosci (2010) 0.93
Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons. Science (2016) 0.93
Identification and differential expression of multiple isoforms of mouse Coiled-coil-DIX1 (Ccd1), a positive regulator of Wnt signaling. Brain Res Mol Brain Res (2005) 0.92
Dapper antagonist of catenin-1 cooperates with Dishevelled-1 during postsynaptic development in mouse forebrain GABAergic interneurons. PLoS One (2013) 0.88
Molecular basis of Wnt activation via the DIX domain protein Ccd1. J Biol Chem (2010) 0.87
Association of adenomatous polyposis coli (APC) gene polymorphisms with autism spectrum disorder (ASD). Am J Med Genet B Neuropsychiatr Genet (2007) 0.87
Expression of mouse Coiled-coil-DIX1 (Ccd1), a positive regulator of Wnt signaling, during embryonic development. Gene Expr Patterns (2005) 0.87
DIXDC1 increases the invasion and migration ability of non-small-cell lung cancer cells via the PI3K-AKT/AP-1 pathway. Mol Carcinog (2013) 0.84
Glial wingless/Wnt regulates glutamate receptor clustering and synaptic physiology at the Drosophila neuromuscular junction. J Neurosci (2014) 0.83
Wnt signaling stabilizes the DIXDC1 protein through decreased ubiquitin-dependent degradation. Cancer Sci (2009) 0.81
The history of lithium therapy. Bipolar Disord (2009) 0.81
A rare WNT1 missense variant overrepresented in ASD leads to increased Wnt signal pathway activation. Transl Psychiatry (2013) 0.81
Abnormal behavior in mice mutant for the Disc1 binding partner, Dixdc1. Transl Psychiatry (2011) 0.80
A glutamatergic network mediates lithium response in bipolar disorder as defined by epigenome pathway analysis. Pharmacogenomics (2015) 0.79
Dixdc1 targets CyclinD1 and p21 via PI3K pathway activation to promote Schwann cell proliferation after sciatic nerve crush. Biochem Biophys Res Commun (2016) 0.79
Hyponeophagia: a measure of anxiety in the mouse. J Vis Exp (2011) 0.78
GSK-3β and MMP-9 Cooperate in the Control of Dendritic Spine Morphology. Mol Neurobiol (2016) 0.78
Next-generation sequencing of endoscopic biopsies identifies ARID1A as a tumor-suppressor gene in Barrett's esophagus. Oncogene (2013) 1.33
Metamoodics: meta-analysis and bioinformatics resource for mood disorders. Mol Psychiatry (2013) 0.81
Search for common targets of lithium and valproic acid identifies novel epigenetic effects of lithium on the rat leptin receptor gene. Transl Psychiatry (2015) 0.80