Published in Front Neurosci on October 06, 2016
Lipid glycosylation: a primer for histochemists and cell biologists. Histochem Cell Biol (2016) 0.75
Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease. Sci Rep (2017) 0.75
Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice. J Neurosci (2001) 2.29
Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects. Proc Natl Acad Sci U S A (1999) 1.95
Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms. Proc Natl Acad Sci U S A (2009) 1.87
Brain white-matter volume loss and glucose hypometabolism precede the clinical symptoms of Huntington's disease. J Nucl Med (2006) 1.83
Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical "disconnection". Neuroimage (2009) 1.72
Interruption of ganglioside synthesis produces central nervous system degeneration and altered axon-glial interactions. Proc Natl Acad Sci U S A (2005) 1.43
Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease. Neuroimage (2008) 1.40
Brain gangliosides in axon-myelin stability and axon regeneration. FEBS Lett (2009) 1.30
Sphingolipids and gangliosides of the nervous system in membrane function and dysfunction. FEBS Lett (2009) 1.25
Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice. J Biol Chem (2010) 1.25
Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features. J Neurochem (2010) 1.25
In vivo evidence of cerebellar atrophy and cerebral white matter loss in Huntington disease. Neurology (2004) 1.24
Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease. J Neurosci (2011) 1.09
Huntington's disease: clinical presentation and treatment. Int Rev Neurobiol (2011) 1.07
Functions of sphingolipid metabolism in mammals--lessons from genetic defects. Biochim Biophys Acta (2008) 1.03
Diffusion tensor imaging in Huntington's disease reveals distinct patterns of white matter degeneration associated with motor and cognitive deficits. Brain Imaging Behav (2011) 0.98
Impaired ganglioside metabolism in Huntington's disease and neuroprotective role of GM1. J Neurosci (2010) 0.98
Multimodal MRI analysis of the corpus callosum reveals white matter differences in presymptomatic and early Huntington's disease. Cereb Cortex (2012) 0.97
Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease. Neurobiol Dis (2015) 0.96
FTY720 (fingolimod) is a neuroprotective and disease-modifying agent in cellular and mouse models of Huntington disease. Hum Mol Genet (2013) 0.95
Glycolipid and ganglioside metabolism imbalances in Huntington's disease. Neurobiol Dis (2007) 0.93
White matter connectivity reflects clinical and cognitive status in Huntington's disease. Neurobiol Dis (2014) 0.90
Targeting glial cells to elucidate the pathogenesis of Huntington's disease. Mol Neurobiol (2010) 0.88
Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease. Hum Mol Genet (2015) 0.87
Reduced functional brain connectivity prior to and after disease onset in Huntington's disease. Neuroimage Clin (2013) 0.87
MRI measures of corpus callosum iron and myelin in early Huntington's disease. Hum Brain Mapp (2013) 0.87
Mutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytes. Neuron (2015) 0.85
Cerebellar lipid differences between R6/1 transgenic mice and humans with Huntington's disease. J Neurochem (2010) 0.82
Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease. Hum Mol Genet (2015) 0.81
Neurobiology of human oligodendrocytes in culture. J Neurosci Res (1990) 0.80