J F Smits

Author PubWeight™ 90.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure. Nat Med 1999 4.85
2 Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome. Nat Med 2001 2.46
3 Matrix metalloproteinase inhibition after myocardial infarction: a new approach to prevent heart failure? Circ Res 2001 2.38
4 Chronic myocardial infarction in the mouse: cardiac structural and functional changes. Cardiovasc Res 1999 2.25
5 The infarcted myocardium: simply dead tissue, or a lively target for therapeutic interventions. Cardiovasc Res 1999 2.06
6 Real-time imaging of apoptotic cell-membrane changes at the single-cell level in the beating murine heart. Nat Med 2001 1.91
7 Estrogen modulates AT1 receptor gene expression in vitro and in vivo. Circulation 1998 1.69
8 Dynamics of cardiac wound healing following myocardial infarction: observations in genetically altered mice. Acta Physiol Scand 2001 1.37
9 Antihypertensive effect of propranolol in conscious spontaneously hypertensive rats: central hemodynamics, plasma volume, and renal function during beta-blockade with propranolol. J Cardiovasc Pharmacol 1983 1.25
10 Short-term and long-term blood pressure and heart rate variability in the mouse. Am J Physiol Regul Integr Comp Physiol 2000 1.25
11 Evidence for a novel angiotensin II receptor involved in angiogenesis in chick embryo chorioallantoic membrane. Am J Physiol 1993 1.22
12 Cardiomyocyte death induced by myocardial ischemia and reperfusion: measurement with recombinant human annexin-V in a mouse model. Circulation 2000 1.18
13 Failure of atriopeptin II to cause arterial vasodilation in the conscious rat. Circ Res 1985 1.11
14 Markers of apoptosis in cardiovascular tissues: focus on Annexin V. Cardiovasc Res 2000 1.10
15 Possible role of nitric oxide-cyclic GMP pathway in object recognition memory: effects of 7-nitroindazole and zaprinast. Eur J Pharmacol 1997 1.06
16 DNA synthesis in the non-infarcted cardiac interstitium after left coronary artery ligation in the rat: effects of captopril. J Mol Cell Cardiol 1991 1.05
17 Beta-catenin, an inducer of uncontrolled cell proliferation and migration in malignancies, is localized in the cytoplasm of vascular endothelium during neovascularization after myocardial infarction. Am J Pathol 2000 1.05
18 Alpha 1-adrenoreceptor blockade reduces the angiotensin II-induced vascular smooth muscle cell DNA synthesis in the rat thoracic aorta and carotid artery. Circ Res 1992 1.03
19 Cardiovascular phenotyping in mice. Cardiovasc Res 1998 1.02
20 Pulmonary artery remodeling differs in hypoxia- and monocrotaline-induced pulmonary hypertension. Am J Respir Crit Care Med 1998 1.02
21 Structural alterations in heart valves during left ventricular pressure overload in the rat. Lab Invest 1994 1.01
22 Cardiac remodeling after myocardial infarction is impaired in IGF-1 deficient mice. Cardiovasc Res 2001 1.00
23 A homologue of Drosophila tissue polarity gene frizzled is expressed in migrating myofibroblasts in the infarcted rat heart. Nat Med 1997 0.99
24 AT2 receptor blockade reduces cardiac interstitial cell DNA synthesis and cardiac function after rat myocardial infarction. J Mol Cell Cardiol 1998 0.97
25 Increased expression of fibronectin isoforms after myocardial infarction in rats. J Mol Cell Cardiol 1997 0.95
26 Distribution and functional significance of cardiac angiotensin converting enzyme in hypertrophied rat hearts. Circulation 1993 0.95
27 Expression and localization of renin and angiotensinogen in rat heart after myocardial infarction. Am J Physiol 1996 0.93
28 Transmural changes in mast cell density in rat heart after infarct induction in vivo. J Pathol 1995 0.92
29 The role of the baroreceptor reflex in the cardiovascular effects of propranolol in the conscious spontaneously hypertensive rat. Clin Sci (Lond) 1979 0.90
30 Effects of chemical sympathectomy on angiotensin II-induced neointimal growth in the balloon-injured rat carotid artery. J Vasc Res 1998 0.89
31 Increased expression of a homologue of drosophila tissue polarity gene "frizzled" in left ventricular hypertrophy in the rat, as identified by subtractive hybridization. J Mol Cell Cardiol 1996 0.88
32 Liver blood flow measurement in the rat. The electromagnetic versus the microsphere and the clearance methods. J Pharmacol Methods 1989 0.87
33 Preferential renal vasodilator effects of CGP 22979A in conscious spontaneously hypertensive rats. J Pharmacol Exp Ther 1985 0.86
34 Delayed but not immediate captopril therapy improves cardiac function in conscious rats, following myocardial infarction. J Mol Cell Cardiol 1991 0.85
35 Activation of angiotensin-converting enzyme expression in infarct zone following myocardial infarction. Am J Physiol 1995 0.85
36 Baroreflex sensitivity during the development of spontaneous hypertension in rats. Clin Sci (Lond) 1982 0.85
37 Chronic local infusion into the renal artery of unrestrained rats. Am J Physiol 1983 0.84
38 Intrahypothalamic serotonin and cardiovascular control in rats. Brain Res 1976 0.84
39 Antihypertensive mechanisms of beta-adrenoceptor blockade: a review. Clin Exp Hypertens A 1985 0.84
40 Systemic and regional hemodynamic actions of calcium entry blockers in conscious spontaneously hypertensive rats. Eur J Pharmacol 1985 0.84
41 Dissociation of pulmonary vascular remodeling and right ventricular pressure in tissue angiotensin-converting enzyme-deficient mice under conditions of chronic alveolar hypoxia. Am J Respir Crit Care Med 2001 0.84
42 Frizzled 2 is transiently expressed in neural crest-containing areas during development of the heart and great arteries in the mouse. Anat Embryol (Berl) 2001 0.84
43 Overexpression of components of the Frizzled-Dishevelled cascade results in apoptotic cell death, mediated by beta-catenin. Exp Cell Res 2001 0.83
44 Angiotensin I converting enzyme inhibitors and cardiac remodeling. Basic Res Cardiol 1991 0.83
45 Microvascular actions of calcium channel antagonists. Eur J Pharmacol 1991 0.82
46 Fatty acid-binding proteinuria diagnoses myocardial infarction in the rat. Mol Cell Biochem 1993 0.82
47 Effects of ketanserin on hemodynamics and baroreflex effects in conscious spontaneously hypertensive rats. J Cardiovasc Pharmacol 1987 0.81
48 Preferential renal and mesenteric vasodilation induced by barnidipine and amlodipine in spontaneously hypertensive rats. Naunyn Schmiedebergs Arch Pharmacol 2001 0.81
49 Renal selective N-acetyl-gamma-glutamyl prodrugs: a study on the mechanism of activation of the renal vasodilator prodrug CGP 22979. Br J Pharmacol 1990 0.81
50 Pharmacology of cardiac and vascular remodeling. Annu Rev Pharmacol Toxicol 1995 0.81
51 Activation of afferent renal nerves by intrarenal bradykinin in conscious rats. Am J Physiol 1984 0.81
52 Steady-state disposition of propranolol and its total metabolites in the spontaneously hypertensive rat: chronic subcutaneous vs. intracerebroventricular infusion with osmotic minipumps. J Pharmacol Exp Ther 1979 0.80
53 Local treatment of renal allografts, a promising way to reduce the dosage of immunosuppressive drugs. Comparison of various ways of administering prednisolone. Transplantation 1986 0.80
54 Acute hemodynamic effects of coronary artery ligation in conscious rats. Basic Res Cardiol 1990 0.80
55 Beta-adrenoceptors in kidney tubules of spontaneously hypertensive and normotensive rats. Life Sci 1986 0.80
56 Hemodynamic actions of diuretic agents. Clin Exp Hypertens A 1983 0.80
57 Propranolol in conscious spontaneously hypertensive rats. I. Cardiovascular effects after subcutaneous and intracerebroventricular administration. Naunyn Schmiedebergs Arch Pharmacol 1979 0.80
58 Reduced responsiveness of rat mesenteric resistance artery smooth muscle to phenylephrine and calcium following myocardial infarction. Br J Pharmacol 1997 0.79
59 Doxazosin blocks the angiotensin II-induced smooth muscle cell DNA synthesis in the media, but not in the neointima of the rat carotid artery after balloon injury. Cardiovasc Res 1996 0.79
60 Time-related normalization of maximal coronary flow in isolated perfused hearts of rats with myocardial infarction. Circulation 1996 0.79
61 Heart fatty acid binding protein and cardiac troponin T plasma concentrations as markers for myocardial infarction after coronary artery ligation in mice. Pflugers Arch 2000 0.79
62 Acute renal vascular response to ACE inhibition in two rat strains with different susceptibility to the development of glomerulosclerosis. Nephrol Dial Transplant 1992 0.79
63 Lack of renal vasodilation during intrarenal infusion of synthetic atriopeptin II in conscious intact SHR. Life Sci 1986 0.79
64 Effects of the renal vasodilator prodrug CGP 22 979A and its parent compound CGP 18 137A on renal and central hemodynamics in conscious spontaneously hypertensive rats. J Pharmacol Exp Ther 1985 0.79
65 Renal hemodynamic effects of nonhypotensive doses of angiotensin-converting enzyme inhibitors in hypertension and heart failure rats. J Cardiovasc Pharmacol 1992 0.79
66 Hemodynamic characterization of hypertension induced by chronic intrarenal or intravenous infusion of norepinephrine in conscious rats. Hypertension 1984 0.79
67 Structural adaptation to ischemia in skeletal muscle: effects of blockers of the renin-angiotensin system. J Hypertens 1997 0.79
68 Microcirculatory changes in cremaster muscle during early spontaneous hypertension in the rat. J Hypertens Suppl 1988 0.78
69 Differential effects of general anesthetics on regional vasoconstrictor responses in the rat. Arch Int Pharmacodyn Ther 1987 0.78
70 Behavioral changes following chronic myocardial infarction in rats. Physiol Behav 1994 0.78
71 The osmotic minipump: a new tool in the study of steady-state kinetics of drug distribution and metabolism. J Pharm Pharmacol 1978 0.78
72 Regional haemodynamic effects of dopamine and its prodrugs L-dopa and gludopa in the rat and in the glycerol-treated rat as a model for acute renal failure. Br J Pharmacol 1994 0.77
73 Coronary arterial hyperreactivity and mesenteric arterial hyporeactivity after myocardial infarction in the rat. J Cardiovasc Pharmacol 1997 0.77
74 Increased responsiveness of the vascular bed to angiotensin I, angiotensin II and phenylephrine in acute and chronic ischemic hindlimbs in rats. J Vasc Res 1992 0.77
75 Serotonin-mediated cardiovascular responses to electrical stimulation of the raphe nuclei in the rat. Life Sci 1978 0.77
76 Evaluation of renal function during intrarenal norepinephrine infusion in conscious rats. Ren Physiol 1984 0.77
77 Hemodynamic changes in pseudopregnancy in chronically instrumented conscious rats. Am J Physiol 1997 0.77
78 The influence of angiotensin II-induced increase in aortic wall mass on compliance in rats in vivo. Cardiovasc Res 1997 0.76
79 Haemodynamic effects of bromocriptine in the conscious spontaneously hypertensive rat. J Pharm Pharmacol 1984 0.76
80 Antihypertensive therapy and adaptive mechanisms in peripheral ischemia. Hypertension 1993 0.76
81 Role of sensory renal nerves in the development of spontaneous hypertension in rats. Clin Exp Hypertens A 1987 0.76
82 Blood pressure response to chronic low-dose intrarenal noradrenaline infusion in conscious rats. Clin Sci (Lond) 1983 0.76
83 'Quality of life' after therapy in rats with myocardial infarction: dissociation between hemodynamic and behavioral improvement. Eur J Pharmacol 1996 0.76
84 Antihypertensive and haemodynamic properties of the renal vasodilator CGP 22 979A in conscious spontaneously hypertensive rats. J Hypertens Suppl 1985 0.76
85 Early captopril treatment inhibits DNA synthesis in endothelial cells and normalization of maximal coronary flow in infarcted rat hearts. Cardiovasc Res 1998 0.76
86 The effect of pentobarbitone anaesthesia and hypothermia on the hepatic clearance of indocyanine green and S(-)-acenocoumarol in the rat. J Pharm Pharmacol 1986 0.76
87 Selective efferent chemical sympathectomy of rat kidneys. Am J Physiol 1985 0.76
88 Effect of chronic blockade of angiotensin II-receptor subtypes on aortic compliance in rats with myocardial infarction. J Cardiovasc Pharmacol 1998 0.76
89 Time-related adaptations in plasma neurohormone levels and hemodynamics after myocardial infarction in the rat. J Card Fail 1998 0.75
90 Hemodynamic effects of activation of renal and mesenteric sensory nerves in rats. Am J Physiol 1989 0.75
91 Acute hemodynamic effects of propranolol in the conscious spontaneously hypertensive rat (SHR) [proceedings]. Br J Pharmacol 1980 0.75
92 Impaired arterial reactivity following cytomegalovirus infection in the immunosuppressed rat. Br J Pharmacol 1996 0.75
93 Effects of propranolol on baroreceptor reflex sensitivity in the conscious spontaneously hypertensive rats (SHR) [proceedings]. Br J Pharmacol 1980 0.75
94 Regional hemodynamic effects of the beta-adrenoceptor blockers tertatolol and propranolol in conscious spontaneously hypertensive rats. Arch Int Pharmacodyn Ther 1986 0.75
95 Adrenoceptors in the kidney: localization and pharmacology. Clin Exp Hypertens A 1987 0.75
96 Role of baroreflex activation in the regional hemodynamic effects of the beta-blockers tertatolol and propranolol in conscious spontaneously hypertensive rats. Am J Nephrol 1986 0.75
97 Pharmacological evidence for rapid destruction of efferent renal nerves in rats by intrarenal infusion of 6-hydroxydopamine. J Hypertens Suppl 1985 0.75
98 Two weeks of intermittent dobutamine therapy restores cardiac performance and inotropic responsiveness in conscious rats with heart failure. J Cardiovasc Pharmacol 1991 0.75
99 Physiological role of ANP under resting and volume expanded conditions in normotensive rats. Life Sci 1990 0.75
100 Cardiac function in a rat model of chronic aortic stiffness. Am J Physiol 1997 0.75
101 Calcium antagonists: systemic and regional haemodynamic effects in conscious spontaneously hypertensive rats (SHR). J Hypertens Suppl 1984 0.75
102 Role of the baroreflex in beta 2-sympathomimetic induced tachycardia in male rats. Eur J Obstet Gynecol Reprod Biol 1993 0.75
103 Cardiovascular effects of chronic infusion of propranolol in the conscious spontaneously hypertensive rat. J Pharm Pharmacol 1980 0.75
104 Role of afferent renal nerves in spontaneous hypertension in rats. Hypertension 1989 0.75
105 Pressure but not angiotensin II-induced increases in wall mass or tone influences static and dynamic aortic mechanics. J Hypertens 1999 0.75
106 Beneficial hemodynamic effects of two weeks' milrinone treatment in conscious rats with heart failure. Eur J Pharmacol 1990 0.75
107 Hemodynamic effects of the arteriolar vasodilators hydralazine, dihydralazine and endralazine in the conscious spontaneously hypertensive rat. Eur J Pharmacol 1983 0.75
108 Target organ directed drug delivery: evaluation of renal infusion of chromium-51 ethylenediaminetetraacetate and sodium o-[125I]iodohippurate in the Wistar Kyoto rat. J Pharm Sci 1986 0.75
109 Effects of complete renal denervation and selective afferent renal denervation on the hypertension induced by intrarenal norepinephrine infusion in conscious rats. J Hypertens 1989 0.75
110 Pharmacokinetic considerations in target-organ directed drug delivery. Trends Pharmacol Sci 1988 0.75
111 Antihypertensive action of beta-adrenoceptor blocking drugs. The role of intrarenal mechanisms. Am J Hypertens 1989 0.75
112 Comparison of angiotensin-converting enzyme inhibitors in the rat in perfused hindlimbs and in vivo. Eur J Pharmacol 1992 0.75
113 Role of afferent renal nerves in renal adaptation to sodium restriction in uninephrectomized rats. Acta Physiol Scand 1994 0.75
114 Effect of nitric oxide synthase inhibition on the acetylcholine response in the perfused hind limb of rats. Eur J Pharmacol 1996 0.75
115 Role of basal nitric oxide synthesis in vasoconstrictor hyporeactivity in the perfused rat hindlimb after myocardial infarction: effect of captopril. Cardiovasc Res 1999 0.75
116 Adrenergic stimulation of the rat mesenteric vascular bed: a combined micro- and macrocirculatory study. Pflugers Arch 1987 0.75
117 The concept of cardioreparation: Part 1. Pathophysiology of remodelling. J Cardiovasc Risk 1996 0.75
118 Peripheral vascular alterations during experimental heart failure in the rat. Do they exist? Arterioscler Thromb Vasc Biol 1995 0.75
119 [Organ-oriented administration of drugs; sense and nonsense]. Ned Tijdschr Geneeskd 1989 0.75
120 Long-term renal vasodilator effect of the beta-adrenoceptor blocker tertatolol in conscious spontaneously hypertensive rats. J Cardiovasc Pharmacol 1988 0.75
121 Angiotensin II induces media hypertrophy and hyperreactivity in mesenteric but not epigastric small arteries of the rat. J Vasc Res 1997 0.75
122 The pharmacology of calcium antagonists: a review. J Cardiovasc Pharmacol 1990 0.75
123 Mechanisms of renal vasoconstriction following furosemide in conscious rats. Naunyn Schmiedebergs Arch Pharmacol 1994 0.75
124 Acute arteriolar vasoconstriction following furosemide in conscious spontaneously hypertensive rats. Eur J Pharmacol 1989 0.75
125 Systolic time intervals as indicators for cardiac function in rat models for heart failure. Eur Heart J 1990 0.75
126 Hemodynamic effects of ketanserin in experimental hypertension. Acta Cardiol 1987 0.75
127 The mechanisms of antihypertensive action of beta-adrenergic receptor blocking drugs. Clin Exp Hypertens A 1982 0.75
128 Is the antihypertensive effect of propranolol caused by an action within the central nervous system? J Pharmacol Exp Ther 1980 0.75
129 Renal nerves in hypertension. Miner Electrolyte Metab 1989 0.75
130 Systemic and regional haemodynamic effects of vasodilators in hypertension. Neth J Med 1984 0.75
131 Effects of angiotensin II on cardiac function and peripheral vascular structure during compensated heart failure in the rat. Arterioscler Thromb Vasc Biol 1997 0.75
132 Ouabain improves cardiac function in vivo in rats with heart failure after chronic but not acute treatment. Naunyn Schmiedebergs Arch Pharmacol 1997 0.75
133 Atrial natriuretic factor increases albumin extravasation in conscious rats. Pflugers Arch 1990 0.75