Published in J Exp Med on October 24, 2016
Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing. J Exp Med (2017) 1.37
Single-cell functional and chemosensitive profiling of combinatorial colorectal therapy in zebrafish xenografts. Proc Natl Acad Sci U S A (2017) 0.79
Intravital imaging of metastasis in adult Zebrafish. BMC Cancer (2017) 0.75
Zebrafish in Translational Cancer Research: Insight into Leukemia, Melanoma, Glioma and Endocrine Tumor Biology. Genes (Basel) (2017) 0.75
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A (2005) 167.46
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics (2009) 67.17
STAR: ultrafast universal RNA-seq aligner. Bioinformatics (2012) 25.21
HTSeq--a Python framework to work with high-throughput sequencing data. Bioinformatics (2014) 23.22
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell (1992) 17.50
Purification and characterization of mouse hematopoietic stem cells. Science (1988) 15.99
A severe combined immunodeficiency mutation in the mouse. Nature (1983) 13.99
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Cell (2010) 12.23
Cellular and molecular regulation of muscle regeneration. Physiol Rev (2004) 10.72
Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. Science (2008) 9.25
NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells. Blood (2002) 7.78
Direct isolation of satellite cells for skeletal muscle regeneration. Science (2005) 6.59
Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas. Science (2012) 6.55
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell (1995) 5.58
Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell Stem Cell (2008) 5.09
Highly efficient, functional engraftment of skeletal muscle stem cells in dystrophic muscles. Cell (2008) 4.92
Simple methods for generating and detecting locus-specific mutations induced with TALENs in the zebrafish genome. PLoS Genet (2012) 4.42
scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. Proc Natl Acad Sci U S A (1991) 3.69
BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Curr Biol (2005) 3.68
Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes Dev (2007) 3.45
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature (2011) 3.37
Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development. Science (1995) 3.15
Myc-induced T cell leukemia in transgenic zebrafish. Science (2003) 3.15
Defective lymphoid development in mice lacking Jak3. Science (1995) 3.04
Severe combined immunodeficiency (SCID) in the mouse. Pathology, reconstitution, neoplasms. Am J Pathol (1985) 2.80
Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse. Proc Natl Acad Sci U S A (1996) 2.77
Myoblast fusion: lessons from flies and mice. Development (2012) 2.66
Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation. Blood (2004) 2.46
The role of Stat5a and Stat5b in signaling by IL-2 family cytokines. Oncogene (2000) 2.45
Method for isolation of PCR-ready genomic DNA from zebrafish tissues. Biotechniques (2007) 2.34
High-resolution imaging of the dynamic tumor cell vascular interface in transparent zebrafish. Proc Natl Acad Sci U S A (2007) 2.13
Improved somatic mutagenesis in zebrafish using transcription activator-like effector nucleases (TALENs). PLoS One (2012) 1.85
T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. Cancer Cell (2010) 1.85
Primary tumor genotype is an important determinant in identification of lung cancer propagating cells. Cell Stem Cell (2010) 1.81
Clonal evolution enhances leukemia-propagating cell frequency in T cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activation. Cancer Cell (2014) 1.79
Activated ALK collaborates with MYCN in neuroblastoma pathogenesis. Cancer Cell (2012) 1.66
Current advances in humanized mouse models. Cell Mol Immunol (2012) 1.65
Transplantable progenitors of natural killer cells are distinct from those of T and B lymphocytes. Proc Natl Acad Sci U S A (1986) 1.54
Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature (2015) 1.47
Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma. PLoS One (2009) 1.40
High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia. Blood (2010) 1.34
Imaging hallmarks of cancer in living mice. Nat Rev Cancer (2014) 1.32
Transplantable tumor lines generated in clonal zebrafish. Cancer Res (2006) 1.30
In vivo imaging of tumor-propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcoma. Cancer Cell (2012) 1.28
Sarcomas induced in discrete subsets of prospectively isolated skeletal muscle cells. Proc Natl Acad Sci U S A (2011) 1.20
Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: HuGE review. Genet Med (2004) 1.11
Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8. Proc Natl Acad Sci U S A (1995) 1.11
Mutations in severe combined immune deficiency (SCID) due to JAK3 deficiency. Hum Mutat (2001) 1.04
The genetic and biochemical basis of Omenn syndrome. Immunol Rev (2000) 1.04
Optimized cell transplantation using adult rag2 mutant zebrafish. Nat Methods (2014) 1.01
A Quantitative System for Studying Metastasis Using Transparent Zebrafish. Cancer Res (2015) 0.97
T cell development and activation in Jak3-deficient mice. J Leukoc Biol (1998) 0.97
A new zebrafish model for experimental leukemia therapy. Cancer Biol Ther (2010) 0.95
Early development of human hematopoietic and acquired immune systems in new born NOD/Scid/Jak3null mice intrahepatic engrafted with cord blood-derived CD34 + cells. Int J Hematol (2008) 0.95
FK506 enhances regeneration of axons across long peripheral nerve gaps repaired with collagen guides seeded with allogeneic Schwann cells. Glia (2004) 0.89
Establishment of murine basal cell carcinoma allografts: a potential model for preclinical drug testing and for molecular analysis. J Invest Dermatol (2011) 0.88
Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish. Nat Commun (2016) 0.85
Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish. J Exp Med (2016) 0.85
Failure of effector function of human CD8+ T Cells in NOD/SCID/JAK3⁻/⁻ immunodeficient mice transplanted with human CD34+ hematopoietic stem cells. PLoS One (2010) 0.84
Asymmetric division of clonal muscle stem cells coordinates muscle regeneration in vivo. Science (2016) 0.82
Normal and malignant muscle cell transplantation into immune compromised adult zebrafish. J Vis Exp (2014) 0.80
Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing. J Exp Med (2017) 1.37
Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma. Elife (2017) 0.75
Identification and characterization of T reg-like cells in zebrafish. J Exp Med (2017) 0.75
Single-cell imaging of human cancer xenografts using adult immunodeficient zebrafish. Nat Protoc (2020) 0.75