Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins.

Ras Association-Domain Dimers Bring Proteins Together. Structure (2016) 0.75

The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 187.88

XDS. Acta Crystallogr D Biol Crystallogr (2010) 67.46

Linking crystallographic model and data quality. Science (2012) 12.13

Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site. EMBO J (1986) 2.85

Kinetics of interaction of nucleotides with nucleotide-free H-ras p21. Biochemistry (1990) 2.55

Ras/Rap effector specificity determined by charge reversal. Nat Struct Biol (1996) 2.52

Recognizing and defining true Ras binding domains I: biochemical analysis. J Mol Biol (2005) 1.76

The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proc Natl Acad Sci U S A (2000) 1.68

Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling. Dev Cell (2011) 1.55

Identification of AF-6 and canoe as putative targets for Ras. J Biol Chem (1996) 1.42

Energetics of hydrogen bonds in peptides. Proc Natl Acad Sci U S A (2003) 1.41

AF6 negatively regulates Rap1-induced cell adhesion. J Biol Chem (2005) 1.24

Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localization. J Biol Chem (2004) 1.20

Rasip1 is required for endothelial cell motility, angiogenesis and vessel formation. Dev Biol (2009) 1.10

Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway. Proc Natl Acad Sci U S A (2015) 1.08

Rasip1 mediates Rap1 regulation of Rho in endothelial barrier function through ArhGAP29. Proc Natl Acad Sci U S A (2013) 1.06

COCOMAPS: a web application to analyze and visualize contacts at the interface of biomolecular complexes. Bioinformatics (2011) 1.04

A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors. Genes Dev (2007) 0.98

Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling. Blood (2013) 0.97

Rap1 Spatially Controls ArhGAP29 To Inhibit Rho Signaling during Endothelial Barrier Regulation. Mol Cell Biol (2015) 0.91

The structure of the ternary complex of Krev interaction trapped 1 (KRIT1) bound to both the Rap1 GTPase and the heart of glass (HEG1) cytoplasmic tail. J Biol Chem (2013) 0.90

Cdc42 and k-Ras Control Endothelial Tubulogenesis through Apical Membrane and Cytoskeletal Polarization: Novel Stimulatory Roles for GTPase Effectors, the Small GTPases, Rac2 and Rap1b, and Inhibitory Influence of Arhgap31 and Rasa1. PLoS One (2016) 0.85

Size-exclusion chromatography can identify faster-associating protein complexes and evaluate design strategies. BMC Res Notes (2009) 0.85

Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity. Elife (2016) 0.83