Published in Dev Biol on March 06, 2009
Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet (2010) 1.57
Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling. Dev Cell (2011) 1.55
Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins. Structure (2016) 1.39
Molecular mechanisms controlling vascular lumen formation in three-dimensional extracellular matrices. Cells Tissues Organs (2011) 1.19
HoxA3 is an apical regulator of haemogenic endothelium. Nat Cell Biol (2010) 1.13
Rasip1 mediates Rap1 regulation of Rho in endothelial barrier function through ArhGAP29. Proc Natl Acad Sci U S A (2013) 1.06
Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels. Circ Res (2011) 1.01
Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling. Blood (2013) 0.97
Tubulogenesis during blood vessel formation. Semin Cell Dev Biol (2011) 0.94
Proteomic profiling of cardiac tissue by isolation of nuclei tagged in specific cell types (INTACT). Development (2014) 0.92
Recent advances in vascular development. Curr Opin Hematol (2012) 0.90
Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation. Development (2013) 0.87
The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease. Curr Opin Immunol (2014) 0.86
The matricellular protein CCN1 controls retinal angiogenesis by targeting VEGF, Src homology 2 domain phosphatase-1 and Notch signaling. Development (2015) 0.84
Rap1 signaling in endothelial barrier control. Cell Adh Migr (2014) 0.84
Cdc42 is required for cytoskeletal support of endothelial cell adhesion during blood vessel formation in mice. Development (2015) 0.83
Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity. Elife (2016) 0.83
High-density genotyping of immune loci in Kawasaki disease and IVIG treatment response in European-American case-parent trio study. Genes Immun (2014) 0.82
Rasip1-Mediated Rho GTPase Signaling Regulates Blood Vessel Tubulogenesis via Nonmuscle Myosin II. Circ Res (2016) 0.80
Rasip1 is essential to blood vessel stability and angiogenic blood vessel growth. Angiogenesis (2016) 0.77
Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling. J Cell Biol (2015) 0.77
Regulation of vascular endothelial junction stability and remodeling through Rap1-Rasip1 signaling. Cell Adh Migr (2014) 0.77
Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature. PLoS One (2015) 0.77
Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc Natl Acad Sci U S A (2001) 68.44
The biology of VEGF and its receptors. Nat Med (2003) 32.13
Mechanisms of angiogenesis. Nature (1997) 18.04
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature (1995) 15.15
Vascular-specific growth factors and blood vessel formation. Nature (2000) 14.42
Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo. Dev Biol (2001) 10.32
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature (2007) 9.09
Vasculogenesis. Annu Rev Cell Dev Biol (1995) 5.41
Endothelial cells and VEGF in vascular development. Nature (2005) 4.92
Molecular mechanisms of blood vessel growth. Cardiovasc Res (2001) 3.94
flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors. Development (1993) 3.66
Regulation of vascular morphogenesis by Notch signaling. Genes Dev (2007) 3.10
Vasculogenesis in the day 6.5 to 9.5 mouse embryo. Blood (2000) 2.98
VEGF-receptor signal transduction. Trends Biochem Sci (2003) 2.89
TGF-beta receptor function in the endothelium. Cardiovasc Res (2005) 2.68
Nf1 has an essential role in endothelial cells. Nat Genet (2002) 2.63
Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein. Nature (1995) 2.41
Regulation of angiogenesis by Eph-ephrin interactions. Trends Cardiovasc Med (2007) 2.15
An essential role for Rac1 in endothelial cell function and vascular development. FASEB J (2008) 2.09
Three-dimensional analysis of vascular development in the mouse embryo. PLoS One (2008) 1.74
Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin. Circ Res (2001) 1.71
CD144 (VE-cadherin) is transiently expressed by fetal liver hematopoietic stem cells. Blood (2005) 1.64
Rac regulates endothelial morphogenesis and capillary assembly. Mol Biol Cell (2002) 1.62
Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation. Development (2006) 1.56
R-Ras is a global regulator of vascular regeneration that suppresses intimal hyperplasia and tumor angiogenesis. Nat Med (2005) 1.51
Molecular distinction between arteries and veins. Cell Tissue Res (2003) 1.47
Blood island formation: longstanding observations and modern interpretations. Exp Hematol (2005) 1.44
Vascular endothelial growth factor induction of the angiogenic phenotype requires Ras activation. J Biol Chem (2001) 1.44
Stimulation of angiogenesis by Ras proteins. Biochim Biophys Acta (2004) 1.35
Xl erg: expression pattern and overexpression during development plead for a role in endothelial cell differentiation. Dev Dyn (1999) 1.33
Vascular development: from precursor cells to branched arterial and venous networks. Int J Dev Biol (2005) 1.25
Neovascularization of the Xenopus embryo. Dev Dyn (1997) 1.24
VEGF regulates cell behavior during vasculogenesis. Dev Biol (2000) 1.20
Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localization. J Biol Chem (2004) 1.20
H-ras regulates angiogenesis and vascular permeability by activation of distinct downstream effectors. Circ Res (2008) 1.17
Rho, Rac, Pak and angiogenesis: old roles and newly identified responsibilities in endothelial cells. Cancer Lett (2005) 1.13
Syx, a RhoA guanine exchange factor, is essential for angiogenesis in Vivo. Circ Res (2008) 1.12
Multifaceted role of Rho proteins in angiogenesis. J Mammary Gland Biol Neoplasia (2005) 1.12
Expression of a new G protein-coupled receptor X-msr is associated with an endothelial lineage in Xenopus laevis. Mech Dev (1996) 1.12
Interference with endogenous ras function inhibits cellular responses to wounding. J Cell Biol (1993) 1.07
A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters. Mol Cell Biol (2004) 1.01
Bone morphogenetic proteins and vascular differentiation: BMPing up vasculogenesis. Thromb Haemost (2005) 1.00
p68RacGAP is a novel GTPase-activating protein that interacts with vascular endothelial zinc finger-1 and modulates endothelial cell capillary formation. J Biol Chem (2004) 0.96
Dual contribution of embryonic ventral blood island and dorsal lateral plate mesoderm during ontogeny of hemopoietic cells in Xenopus laevis. J Immunol (1983) 0.95
Novel gene expression domains reveal early patterning of the Xenopus endoderm. Gene Expr Patterns (2003) 0.92
Differential participation of ventral and dorsolateral mesoderms in the hemopoiesis of Xenopus, as revealed in diploid-triploid or interspecific chimeras. Dev Biol (1985) 0.89
RAS and the RAIN/RasIP1 effector. Methods Enzymol (2006) 0.84
Phenotypic analysis of human bone marrow macrophages. Blood Cells (1991) 0.77
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature (2010) 5.81
The genome of the Western clawed frog Xenopus tropicalis. Science (2010) 4.70
Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Mol Cell Biol (2007) 2.67
Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development. Development (2007) 2.50
Dependence of mouse embryonic stem cells on threonine catabolism. Science (2009) 2.40
Xenbase: gene expression and improved integration. Nucleic Acids Res (2009) 2.38
Techniques and probes for the study of Xenopus tropicalis development. Dev Dyn (2002) 2.34
Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes. Development (2004) 2.33
Transdifferentiation of ciliated cells during repair of the respiratory epithelium. Am J Respir Cell Mol Biol (2005) 2.12
Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy. Am J Hum Genet (2007) 1.97
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart. Dev Biol (2003) 1.89
Defining a large set of full-length clones from a Xenopus tropicalis EST project. Dev Biol (2004) 1.87
Prospective isolation and global gene expression analysis of definitive and visceral endoderm. Dev Biol (2007) 1.75
Prospective isolation of skeletal muscle stem cells with a Pax7 reporter. Stem Cells (2008) 1.71
Epithelial dynamics of pancreatic branching morphogenesis. Development (2010) 1.65
Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling. Genes Dev (2008) 1.63
Role of endothelial cells in early pancreas and liver development. Mech Dev (2003) 1.58
Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling. Dev Cell (2011) 1.55
Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease. Dev Dyn (2010) 1.53
Xenbase: expansion and updates of the Xenopus model organism database. Nucleic Acids Res (2012) 1.49
Biphasic Ngn3 expression in the developing pancreas. Dev Dyn (2008) 1.47
Blood vessels restrain pancreas branching, differentiation and growth. Development (2011) 1.35
Sox17 influences the differentiation of respiratory epithelial cells. Dev Biol (2006) 1.33
Global analysis of the transcriptional network controlling Xenopus endoderm formation. Development (2006) 1.22
A new method to remove hybridization bias for interspecies comparison of global gene expression profiles uncovers an association between mRNA sequence divergence and differential gene expression in Xenopus. Nucleic Acids Res (2006) 1.17
HoxA3 is an apical regulator of haemogenic endothelium. Nat Cell Biol (2010) 1.13
BMP and BMP receptor expression during murine organogenesis. Gene Expr Patterns (2009) 1.13
Endothelial-specific expression of WNK1 kinase is essential for angiogenesis and heart development in mice. Am J Pathol (2009) 1.12
Solution structure and backbone dynamics of the KH-QUA2 region of the Xenopus STAR/GSG quaking protein. J Mol Biol (2005) 1.11
Sox17 promotes cell cycle progression and inhibits TGF-beta/Smad3 signaling to initiate progenitor cell behavior in the respiratory epithelium. PLoS One (2009) 1.10
Ligand-induced EpoR internalization is mediated by JAK2 and p85 and is impaired by mutations responsible for primary familial and congenital polycythemia. Blood (2009) 1.07
spib is required for primitive myeloid development in Xenopus. Blood (2008) 1.05
Enhanced XAO: the ontology of Xenopus anatomy and development underpins more accurate annotation of gene expression and queries on Xenbase. J Biomed Semantics (2013) 1.02
Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels. Circ Res (2011) 1.01
Stepwise arteriovenous fate acquisition during mammalian vasculogenesis. Dev Dyn (2011) 1.01
A New Nomenclature of Xenopus laevis Chromosomes Based on the Phylogenetic Relationship to Silurana/Xenopus tropicalis. Cytogenet Genome Res (2015) 1.01
Purification and high-resolution top-down mass spectrometric characterization of human salivary α-amylase. Anal Chem (2012) 1.00
Structure of protein related to Dan and Cerberus: insights into the mechanism of bone morphogenetic protein antagonism. Structure (2013) 0.98
A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer. Dev Biol (2011) 0.97
Members of the DAN family are BMP antagonists that form highly stable noncovalent dimers. J Mol Biol (2012) 0.97
Smad2 and Smad3 coordinately regulate craniofacial and endodermal development. Dev Biol (2004) 0.96
Sizzled-tolloid interactions maintain foregut progenitors by regulating fibronectin-dependent BMP signaling. Dev Cell (2012) 0.95
Tubulogenesis during blood vessel formation. Semin Cell Dev Biol (2011) 0.94
Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus. Development (2012) 0.93
FoxI1e activates ectoderm formation and controls cell position in the Xenopus blastula. Development (2007) 0.93
Novel gene expression domains reveal early patterning of the Xenopus endoderm. Gene Expr Patterns (2003) 0.92
Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells. Dev Biol (2013) 0.92
Improved cre reporter transgenic Xenopus. Dev Dyn (2009) 0.92
Molecular control of liver development. Clin Liver Dis (2006) 0.91
Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature. PLoS One (2013) 0.91
Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes. Dis Model Mech (2010) 0.90
EphB3 marks delaminating endocrine progenitor cells in the developing pancreas. Dev Dyn (2012) 0.89
Inner arm dynein 1 is essential for Ca++-dependent ciliary reversals in Tetrahymena thermophila. Cell Motil Cytoskeleton (2002) 0.86
Prolonged FGF signaling is necessary for lung and liver induction in Xenopus. BMC Dev Biol (2012) 0.86
Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos. Circ Res (2013) 0.86
Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line. Am J Physiol Endocrinol Metab (2013) 0.85
The core endodermal gene network of vertebrates: combining developmental precision with evolutionary flexibility. Bioessays (2008) 0.84
New doxycycline-inducible transgenic lines in Xenopus. Dev Dyn (2011) 0.84
Antimicrobial properties of commercial annatto extracts against selected pathogenic, lactic acid, and spoilage microorganisms. J Food Prot (2003) 0.84
Crosstalk between the developing pancreas and its blood vessels: an evolving dialog. Semin Cell Dev Biol (2012) 0.84
Negative regulation of Smad2 by PIASy is required for proper Xenopus mesoderm formation. Development (2004) 0.84
CRIM1 complexes with ß-catenin and cadherins, stabilizes cell-cell junctions and is critical for neural morphogenesis. PLoS One (2012) 0.83
Role of cystathionine beta-lyase in catabolism of amino acids to sulfur volatiles by genetic variants of Lactobacillus helveticus CNRZ 32. Appl Environ Microbiol (2007) 0.83
A dynamic requirement for community interactions during Xenopus myogenesis. Int J Dev Biol (2002) 0.83
Determining the impact of varying levels of cherry powder and starter culture on quality and sensory attributes of indirectly cured, emulsified cooked sausages. Meat Sci (2011) 0.82
Overexpression of Lactobacillus casei D-hydroxyisocaproic acid dehydrogenase in cheddar cheese. Appl Environ Microbiol (2004) 0.82
The efficiency of Xenopus primordial germ cell migration depends on the germplasm mRNA encoding the PDZ domain protein Grip2. Differentiation (2007) 0.82
A Molecular atlas of Xenopus respiratory system development. Dev Dyn (2014) 0.82
Bioautography and chemical characterization of antimicrobial compound(s) in commercial water-soluble annatto extracts. J Agric Food Chem (2005) 0.81
Comparison of volatile compounds in water- and oil-soluble annatto (Bixa orellana L.) extracts. J Agric Food Chem (2002) 0.81
Resolution of defective dorsal aortae patterning in Sema3E-deficient mice occurs via angiogenic remodeling. Dev Dyn (2013) 0.80
Par6b regulates the dynamics of apicobasal polarity during development of the stratified Xenopus epidermis. PLoS One (2013) 0.79
Gene regulatory networks governing lung specification. J Cell Biochem (2014) 0.79
Reducing sodium levels in frankfurters using a natural flavor enhancer. Meat Sci (2012) 0.78
Pdx1 regulates pancreas tubulogenesis and E-cadherin expression. Development (2016) 0.78
Molecular components of the endoderm specification pathway in Xenopus tropicalis. Dev Dyn (2003) 0.78
The Xenbase literature curation process. Database (Oxford) (2013) 0.76
Organogenesis: making pancreas from liver. Curr Biol (2003) 0.75
The developing endothelium in action. Semin Cell Dev Biol (2011) 0.75
Partitioning behavior of Alkan-1-ols between milkfat and aqueous phases as influenced by temperature. J Agric Food Chem (2005) 0.75
Reducing sodium levels in frankfurters using naturally brewed soy sauce. Meat Sci (2011) 0.75
Homogenization and lipase treatment of milk and resulting methyl ketone generation in blue cheese. J Agric Food Chem (2014) 0.75